The Host Adapted Fungal Pathogens of Pneumocystis Genus Utilize Genic Regional Centromeres.

Autor: Cissé OH; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA., Curran S; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA., Folco HD; Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Liu Y; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA., Bishop L; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA., Wang H; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA., Fischer ER; Microscopy Unit, Research Technologies Branch, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA., Davis AS; Diagnostic Medicine/Pathobiology, Kansas State University College of Veterinary Medicine, Manhattan, USA., Babb-Biernacki S; Museum of Natural Science and Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana, USA., Doyle VP; Department of Plant Pathology and Crop Physiology, Lousiana State University AgCenter, Baton Rouge, Louisiana, USA., Richards JK; Department of Plant Pathology and Crop Physiology, Lousiana State University AgCenter, Baton Rouge, Louisiana, USA., Hassan SA; Bioinformatics and Computational Biosciences Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Dekker JP; Bacterial Pathogenesis and Antimicrobial Resistance Unit, National Institute of Allergy, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.; Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA., Khil PP; Bacterial Pathogenesis and Antimicrobial Resistance Unit, National Institute of Allergy, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.; Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA., Brenchley JM; Laboratory of Viral Diseases, National Institute of Allergy, and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Grewal S; Laboratory of Biochemistry and Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA., Cushion M; Department of Internal Medicine, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA., Ma L; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA., Kovacs JA; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 12. Date of Electronic Publication: 2023 May 12.

Magnesium, calcium and zinc [N2N'] heteroscorpionate complexes

Autor: Luna Barros, M, Cushion, M, Schwarz, A, Turner, Z, Mountford, P

Publikováno v: Dalton Transactions. 48

A new family of sterically demanding N2N′ heteroscorpionate pro-ligands (HC(tBu2pz)2SiMe2N(H)R (R = iPr, tBu, Ph, Xyl)) has been prepared via a straightforward modular synthetic route. An extensive study into the synthesis and characterisation of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::870f83d2a39ab97726e02c84fbf2451b
http://ora.ox.ac.uk/objects/uuid:

Development of highly active anti-Pneumocystis bisbenzamidines: insight into the influence of selected substituents on the in vitro activity† †Electronic supplementary information (ESI) available: Details of synthetic procedures, characterization data and NMR spectra of newly reported compounds. See DOI: 10.1039/c7md00445a

Autor: Maciejewska, D., Żabiński, J., Rezler, M., Kaźmierczak, P., Collins, M. S., Ficker, L., Cushion, M. T.

A detailed SAR study with 21 pentamidine analogues was undertaken. Four new leading structures were identified.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3bdbcc565fe15914a2bc8a7f977a9073
https://europepmc.org/articles/PMC6071923/

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