Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Curtis W Bacon"'
Autor:
Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel
Publikováno v:
eLife, Vol 7 (2018)
The HIV-1 Tat protein hijacks P-TEFb kinase to activate paused RNA polymerase II (RNAP II) at the viral promoter. Tat binds additional host factors, but it is unclear how they regulate RNAP II elongation. Here, we identify the cytoplasmic ubiquitin l
Externí odkaz:
https://doaj.org/article/4861f751eab349dcb5a30cc8610f90bd
Autor:
Curtis W. Bacon, Iván D'Orso
Publikováno v:
Transcription. 10:57-75
Cyclin-dependent kinase 9 (CDK9) is critical for RNA Polymerase II (Pol II) transcription initiation, elongation, and termination in several key biological processes including development, differentiation, and cell fate responses. A broad range of di
Publikováno v:
Cell Cycle. 15:2115-2123
The ability for the eukaryotic cell to transcriptionally respond to various stimuli is critical for the overall homeostasis of the cell, and in turn, the organism. The human RNA polymerase II complex (Pol II), which is responsible for the transcripti
Autor:
Shwu Yuan Wu, Usman Hyder, Iván D'Orso, Tatiana G. Kutateladze, Juan Bayo, Aditi N. Borkar, Ashutosh Shukla, Curtis W. Bacon, Cheng Ming Chiang, Jiuyang Liu, Ashwini Challa
Publikováno v:
Mol Cell
Precise control of the RNA polymerase II (Pol II) cycle, including pausing and pause release, maintains transcriptional homeostasis and organismal functions. Despite previous work to understand individual transcription steps, we reveal a mechanism th
Autor:
Gwendolyn M. Jang, Billy W. Newton, Tyler B. Faust, Amit Weiss, Yang Li, Curtis W. Bacon, Bhargavi Jayaraman, Iván D'Orso, Nevan J. Krogan, Alan D. Frankel
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
The HIV-1 Tat protein hijacks P-TEFb kinase to activate paused RNA polymerase II (RNAP II) at the viral promoter. Tat binds additional host factors, but it is unclear how they regulate RNAP II elongation. Here, we identify the cytoplasmic ubiquitin l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1a5649d9b49f9d1a8ded005eb18d4e
https://escholarship.org/uc/item/4vz465dt
https://escholarship.org/uc/item/4vz465dt
Autor:
Elizabeth A. McMillan, Jennifer L. McCann, Ryan P. McNamara, Curtis W. Bacon, Iván D'Orso, Jonathan E. Reeder
SummaryThe transition from transcription initiation to elongation at promoters of primary response genes (PRGs) in metazoan cells is controlled by inducible transcription factors, which utilize P-TEFb to phosphorylate RNA polymerase II (Pol II) in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650f99a79b8da129ac2d510e3096e97a
https://europepmc.org/articles/PMC4714561/
https://europepmc.org/articles/PMC4714561/