Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Curtis Pazderka"'
Autor:
Gabriela Garrastazu Pereira, Tristan Rawling, Michele Pozzoli, Curtis Pazderka, Yongjuan Chen, Colin R. Dunstan, Michael Murray, Fabio Sonvico
Publikováno v:
Nanomaterials, Vol 8, Iss 10, p 825 (2018)
Lipid-based drugs are emerging as an interesting class of novel anticancer drugs with the potential to target specific cancer cell metabolic pathways linked to their proliferation and invasiveness. In particular, ω-3 polyunsaturated fatty acids (PUF
Externí odkaz:
https://doaj.org/article/d8d95d17ca09435d9abe6060a9aad003
Autor:
Md Khalilur Rahman, Balasubrahmanyam Umashankar, Hassan Choucair, Curtis Pazderka, Kirsi Bourget, Yongjuan Chen, Colin R. Dunstan, Tristan Rawling, Michael Murray
Publikováno v:
European Journal of Pharmacology. 939:175470
Mitochondria in tumor cells are functionally different from those in normal cells and could be targeted to develop new anticancer agents. We showed recently that the aryl-ureido fatty acid CTU is the prototype of a new class of mitochondrion-targeted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ca31c6914522ce3382dd8fee069520
https://doi.org/10.1016/j.ejphar.2022.175470
https://doi.org/10.1016/j.ejphar.2022.175470
Autor:
Charles G. Cranfield, Xin Wu, Philip A. Gale, Benjamin B. Noble, Callum Clarke, Megan L. O'Mara, Michael Murray, William Lewis, Hugo MacDermott-Opeskin, Tristan Rawling, Ariane Roseblade, Kirsi Bourget, Curtis Pazderka
Publikováno v:
Chemical Science
Respiring mitochondria establish a proton gradient across the mitochondrial inner membrane (MIM) that is used to generate ATP. Protein-independent mitochondrial uncouplers collapse the proton gradient and disrupt ATP production by shuttling protons b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afc9b71402064df562109933ddbd66a
https://pubmed.ncbi.nlm.nih.gov/34094462
https://pubmed.ncbi.nlm.nih.gov/34094462
Autor:
Michael Murray, Gabriela Garrastazu Pereira, Yongjuan Chen, Michele Pozzoli, Fabio Sonvico, Colin R. Dunstan, Curtis Pazderka, Tristan Rawling
Lipid-based drugs are emerging as an interesting class of novel anticancer drugs with the potential to target specific cancer cell metabolic pathway linked to their proliferation and invasiveness. In particular, ω−3 polyunsaturated fatty acids (PU
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a887b2dec017639da7c6a1fdc03415a3
https://doi.org/10.20944/preprints201809.0595.v1
https://doi.org/10.20944/preprints201809.0595.v1
Autor:
Michael Murray, Hassan Choucair, Khalilur Rahman, Yongjuan Chen, Nooshin Koolaji, Curtis Pazderka, Kirsi Bourget, Bala Umashankar, Yassir Al-Zubaidi, Tristan Rawling
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 129
© 2019 Elsevier B.V. We recently developed a novel aryl-urea fatty acid (CTU; 16({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)hexadecanoic acid) that impaired the viability of MDA-MB-231 breast cancer cells in vitro and in mouse xenograft mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e64fd992459afa5028d914dbe8a114
https://pubmed.ncbi.nlm.nih.gov/30597206
https://pubmed.ncbi.nlm.nih.gov/30597206
Publikováno v:
Current medicinal chemistry. 27(10)
Omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acids (PUFAs) play crucial and often opposing regulatory roles in health and in pathological conditions. n-3 and n-6 PUFA undergo biotransformation to parallel series of lipid mediators that are p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a71d99c011cdf2dba462d2138f64bd9
https://pubmed.ncbi.nlm.nih.gov/30259807
https://pubmed.ncbi.nlm.nih.gov/30259807
Autor:
Michele Pozzoli, Fabio Sonvico, Colin R. Dunstan, Curtis Pazderka, Michael Murray, Gabriela Garrastazu Pereira, Yongjuan Chen, Tristan Rawling
Publikováno v:
Nanomaterials, Vol 8, Iss 10, p 825 (2018)
Nanomaterials
Volume 8
Issue 10
Nanomaterials
Volume 8
Issue 10
Lipid-based drugs are emerging as an interesting class of novel anticancer drugs with the potential to target specific cancer cell metabolic pathways linked to their proliferation and invasiveness. In particular, &omega
3 polyunsaturated fatty a
3 polyunsaturated fatty a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba06817d22cf1b7357510d1835544389
https://doi.org/10.3390/nano8100825
https://doi.org/10.3390/nano8100825
© 2015 Elsevier Inc. All rights reserved. Lipids have the potential for development as anticancer agents. Endogenous membrane lipids, such as ceramides and certain saturated fatty acids, have been found to modulate the viability of tumor cells. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56abf3f68698413c1a3c308425b9bcbd
https://hdl.handle.net/10453/35762
https://hdl.handle.net/10453/35762