Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Curtis L. Patton"'
Publikováno v:
Advanced Chemicobiology Research. :31-36
African sleeping sickness is an invariably fatal disease caused by Trypanosoma brucei group trypanosomes and transmitted by the bite of a Tsetse fly. In the human bloodstream, there are two main forms: long slender rapidly proliferating forms and bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e9aa7058ceeeea7e81811d0ebb0633
https://doi.org/10.37256/acbr.1120211217
https://doi.org/10.37256/acbr.1120211217
Publikováno v:
Analytical Biochemistry. 238:46-49
A strategy for the design of simple colorimetric assays to follow any process that involves the net generation or consumption of hydrogen ions in aqueous solutions over the pH range of 3–10 is described. This procedure relies upon the measurement o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99f68ab32a0fbcc472704d9a177598b8
https://doi.org/10.1006/abio.1996.0248
https://doi.org/10.1006/abio.1996.0248
Autor:
David G. Reid, John M. Walker, Curtis L. Patton, Charles E. Egwuagu, James F. Young, Andrew J. Edwards, Patricia J. Sweeney, Nabil Elshourbagy
Publikováno v:
Chirality. 8:545-550
Calmidazolium [R24571, 1-[bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-[(2,4- dichlorophenyl)methoxy]ethyl]-1H-imidazolium chloride] is a potent calmodulin inhibitor. This paper describes the synthesis and properties of the enantiomers of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9bcaf962e77108923eabe6ecae960bc
https://doi.org/10.1002/(sici)1520-636x(1996)8:8<545::aid-chir2>3.0.co
https://doi.org/10.1002/(sici)1520-636x(1996)8:8<545::aid-chir2>3.0.co
Publikováno v:
The Journal of Eukaryotic Microbiology. 40:329-335
Rhodamine 123, a membrane potential-specific dye, has been evaluated as a probe to monitor the function of the mitochondrion in long slender bloodstream and procyclic trypomastigotes of several Trypanosoma brucei spp. By epifluorescence microscopy, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15b5c76ad52e4c9426d88c075024e03
https://doi.org/10.1111/j.1550-7408.1993.tb04924.x
https://doi.org/10.1111/j.1550-7408.1993.tb04924.x
Autor:
Alan A. Divo, Krishnamurthy Shyam, Alan C. Sartorelli, Curtis L. Patton, Regina Loomis, Philip G. Penketh
Publikováno v:
ChemInform. 22
Several 1,2,2-tris(sulfonyl) hydrazines, conceived as prodrugs of 1,2-bis (sulfonyl) hydrazines, were synthesized and evaluated for antineoplastic and trypanocidal activities in mice. 1-Methyl-1,2,2-tris (methylsulfonyl) hydrazine emerged as an extre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b3841aa8f37955616c8ba1319497639
https://doi.org/10.1002/chin.199105149
https://doi.org/10.1002/chin.199105149
Autor:
Krishnamurthy Shyam, Curtis L. Patton, Alan A. Divo, S. Buddhu, Alan C. Sartorelli, Philip G. Penketh
Publikováno v:
Acta Tropica. 49:69-72
Long-slender (LS) bloodstream trypomastigotes of brucei group trypanosomes actively transport and accumulate both monoand diamidines (Damper, 1975), although only the latter are strongly trypanocidal when the amidine groups are appropriately spaced (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bc348a04f6c5ae9dba9fd97bcb5dd8
https://doi.org/10.1016/0001-706x(91)90032-f
https://doi.org/10.1016/0001-706x(91)90032-f
Synthesis and evaluation of 1,2,2-tris(sulfonyl)hydrazines as antineoplastic and trypanocidal agents
Autor:
Regina Loomis, Curtis L. Patton, Krishnamurthy Shyam, Alan C. Sartorelli, Alan A. Divo, Philip G. Penketh
Publikováno v:
Journal of Medicinal Chemistry. 33:2259-2264
Several 1,2,2-tris(sulfonyl) hydrazines, conceived as prodrugs of 1,2-bis (sulfonyl) hydrazines, were synthesized and evaluated for antineoplastic and trypanocidal activities in mice. 1-Methyl-1,2,2-tris (methylsulfonyl) hydrazine emerged as an extre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b35505cbca37cb3654bb3cae7bb664b
https://doi.org/10.1021/jm00170a033
https://doi.org/10.1021/jm00170a033
Publikováno v:
Molecular and Biochemical Parasitology. 38:121-134
Two acidic phosphoproteins of Plasmodium berghei origin, of 65 and 46 kDa, are associated with the plasma membrane of the host mouse erythrocyte. The 65-kDa protein partitions between a soluble and particulate phase upon host cell lysis, whereas the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fedc176dc86b90375248e6f8b329fe18
https://doi.org/10.1016/0166-6851(90)90212-5
https://doi.org/10.1016/0166-6851(90)90212-5
Autor:
Curtis L. Patton
Publikováno v:
Edward Bouchet: The First African-American Doctorate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79785a46411e545f8a3ec4d1e5edbae8
https://doi.org/10.1142/9789812777737_0001
https://doi.org/10.1142/9789812777737_0001
Publikováno v:
Molecular and biochemical parasitology. 109(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d46cb63b16589baf49b70a68073c24
https://pubmed.ncbi.nlm.nih.gov/10960180
https://pubmed.ncbi.nlm.nih.gov/10960180