Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Curtis G. Jones"'
Autor:
Adam J. Kanack, Curtis G. Jones, Bandana Singh, Rachel R. Leger, Noah P. Splinter, Nahla M. Heikal, Rajiv K. Pruthi, Dong Chen, Gemlyn George, Mouhamed Y. Abou-Ismail, Geoffrey D. Wool, Krishna Gundabolu, Anand Padmanabhan
Publikováno v:
Blood. 140:2722-2729
Heparin-induced thrombocytopenia (HIT) is suspected much more often than it is confirmed. Technically simple platelet factor 4 (PF4)-polyanion enzyme-linked immunosorbent assays (ELISAs) are sensitive but nonspecific. In contrast, accurate functional
Publikováno v:
ACS Biomaterials Science & Engineering. 7:1600-1607
Because dysfunctions of endothelial cells are involved in many pathologies, in vitro endothelial cell models for pathophysiological and pharmaceutical studies have been a valuable research tool. Although numerous microfluidic-based endothelial models
Because dysfunctions of endothelial cells are involved in many pathologies, in vitro endothelial cell models for pathophysiological and pharmaceutical studies have been a valuable research tool. Although numerous microfluidic-based endothelial models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a9780431b5cb86fd4b0d02341b91a0d
Cell line-based liver models are critical tools for liver-related studies. However, the conventional monolayer culture of hepatocytes, the most widely used in vitro model, does not have the extracellular matrix (ECM), which contributes to the three-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940c2ed42b70abf80ea4d6dc9132a4d1
Autor:
Anand Padmanabhan, Ruchika Sharma, Curtis G. Jones, Shannon M. Pechauer, Dong Chen, Rachel Leger, Rajiv K. Pruthi, David A. Garcia, Richard H. Aster, Parisa R. Khalighi, Bethany T. Samuelson Bannow, Brian R. Curtis, Deepti M. Warad, Daniel W. Bougie, Mary W. Redman, Diane E. Grill, Daniel E. Sabath
Publikováno v:
Blood
Heparin-induced thrombocytopenia (HIT) is a life-threatening, prothrombotic, antibody-mediated disorder. To maximize the likelihood of recovery, early and accurate diagnosis is critical. Widely available HIT assays, such as the platelet factor 4 (PF4
From cells-on-a-chip to organs-on-a-chip: scaffolding materials for 3D cell culture in microfluidics
Publikováno v:
Journal of materials chemistry. B. 8(31)
It is an emerging research area to integrate scaffolding materials in microfluidic devices for 3D cell culture (organs-on-a-chip). The technology of organs-on-a-chip holds the potential to obviate the gaps between pre-clinical and clinical studies. A
Publikováno v:
ACS sensors. 5(7)
3D printing has emerged as a robust technique to fabricate reliable and reproducible microfluidic devices. However, a limitation of 3D-printed devices has been the low transparency even when printed in a "clear" material. There are currently no repor
A microfibrous ECM fabricated by electrospinning silk fibroin can modulate the energy metabolism, amino acids bioavailability, and integrins expression in hepatocytes, making the cells more physiologically relevant.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92db140943c10358798856e51ad9a697
https://doi.org/10.26434/chemrxiv.11739312.v1
https://doi.org/10.26434/chemrxiv.11739312.v1
We developed a novel microfluidic system that enables automated and near real-time quantitation of indole release kinetics from biofilms.Now published at https://www.sciencedirect.com/science/article/pii/S0924424720311031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f744ed1570f10a3c46c1125f3289b2
https://doi.org/10.26434/chemrxiv.11372217
https://doi.org/10.26434/chemrxiv.11372217
Autor:
Curtis G. Jones, Chengpeng Chen
A low-cost and translational TEER (trans-endothelial/epithelial electric resistance) meter was designed, fabricated, validated, and applied in this paper. TEER is a critical tool to quantitate the integrity of biological barriers. Commercially availa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eacf099618de0d50c4f81247a74b2e4
https://doi.org/10.26434/chemrxiv.11374260.v1
https://doi.org/10.26434/chemrxiv.11374260.v1