Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction.

Autor: Jingtao Lu, Michael-Rock Goldsmith, Christopher M Grulke, Daniel T Chang, Raina D Brooks, Jeremy A Leonard, Martin B Phillips, Ethan D Hypes, Matthew J Fair, Rogelio Tornero-Velez, Jeffre Johnson, Curtis C Dary, Yu-Mei Tan

Publikováno v: PLoS Computational Biology, Vol 12, Iss 2, p e1004495 (2016)

Developing physiologically-based pharmacokinetic (PBPK) models for chemicals can be resource-intensive, as neither chemical-specific parameters nor in vivo pharmacokinetic data are easily available for model construction. Previously developed, well-p

Externí odkaz: https://doaj.org/article/af7f253fb369425d825481fdd93d6280

PAVA: physiological and anatomical visual analytics for mapping of tissue-specific concentration and time-course data

Autor: Daniel T. Chang, Curtis C. Dary, Rogelio Tornero-Velez, Michael-Rock Goldsmith, Thomas R. Transue, Michael Breen

Publikováno v: Journal of Pharmacokinetics and Pharmacodynamics. 37:277-287

We describe the development and implementation of a Physiological and Anatomical Visual Analytics tool (PAVA), a web browser-based application, used to visualize experimental/simulated chemical time-course data (dosimetry), epidemiological data and P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bac850ced462923c229f8d7eda738ca
https://doi.org/10.1007/s10928-010-9160-6

Role of Laboratory Sampling Devices and Laboratory Subsampling Methods in Representative Sampling Strategies

Autor: Brian Schumacher, Curtis C. Dary, John M. Nocerino

Publikováno v: Environmental Forensics. 6:35-44

Sampling is the act of selecting items from a specified population in order to estimate the parameters of that population (e.g., selecting soil samples to characterize the properties at an environmental site). Sampling occurs at various levels and ti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6d95e8c289b0ee16f35bbced66754c10
https://doi.org/10.1080/15275920590913903

List of Contributors

Autor: Angela Aliberti, Patrick Allard, Arturo Anadón, Vellareddy Anantharam, Anthony E. Archibong, Adam D. Aulbach, Aryamitra Banerjee, Leah D. Banks, Frank A. Barile, Sudheer R. Beedanagari, Enrico Bergamaschi, Sneha P. Bhatia, Karyn Bischoff, Víctor Castellano, Daniel T. Chang, James J. Chen, Deborah Citrin, Rory Conolly, R.W. Coppock, Lucio G. Costa, T.V. Damodaran, Kellye K. Daniels, Curtis C. Dary, Robin B. Doss, Filipe V. Duarte, Margitta M. Dziwenka, Stephen Edwards, Jorge Estévez, Daniel S. Fabricant, Anna M. Fan, Ali Faqi, Suzanne E. Fenton, Vanessa A Fitsanakis, John Flaskos, Swaran J.S. Flora, Sue M. Ford, Domniki Fragou, Shayne C. Gad, Niels-Christian Ganderup, Dale R. Gardner, Ronette Gehring, Fernando Gil, Saryu Goel, Michael-Rock Goldsmith, Christopher M. Grulke, Mary Gulumian, P.K. Gupta, Ramesh C. Gupta, Sharon Gwaltney-Brant, Alan J Hargreaves, Kelly L. Harris, Holly E. Hatfield, Diane E. Heck, Antonio F. Hernández, Corey J. Hilmas, Evangelia Hondroulis, Darryl B. Hood, Kathryn Hudak, Pasi Huuskonen, Stewart B. Jacobson, Huajun Jin, Laurie B. Joseph, Jun Kanno, Anumantha G. Kanthasamy, Arthi Kanthasamy, Navinchandra M. Kaore, Shilpa N. Kaore, Bhupendra S. Kaphalia, Vesa Karttunen, Greer E. Kaufman, Ravneet Kaur, Hong Duck Kim, Prasada Rao S. Kodavanti, Urmila P. Kodavanti, George A. Kontadakis, Péter Krajcsi, Gopala Krishna, Kavya A. Krishna, Maria Kummu, George D. Kymionis, Michelle A. Lasher, Chen-zhong Li, Wei-Jiun Lin, Bommanna G. Loganathan, Jarkko Loikkanen, Anna E. Lokshin, Marcello Lotti, Tzu-Pin Lu, Yi Lu, Chikezie Madu, Rémi Magnan, Brinda Mahadevan, Jane A. Mantey, María Rosa Martínez-Larrañaga, Vincent P. Meador, Dejan Milatovic, Pushpinder K. Multani, Päivi Myllynen, Kirsi Myöhänen, Rekek Negga, Jairo Nelson, Brian M. Nolen, Meliton N. Novilla, Stephanie Padilla, Carlos M. Palmeira, Kip E. Panter, Markku Pasanen, Daniel J. Patrick, Sofia Pavanello, Olavi Pelkonen, Claudia Pellacani, Michael A. Pellizzon, Andrew D. Penman, Martin Phillips, Jason Pitt, Argyro Plaka, Aramandla Ramesh, Kausik Ray, Casey E. Reed, Jenni Repo, Matthew R. Ricci, Anabela P. Rolo, Magdalini Sachana, Heidi Sahlman, Nitin Saini, William F. Salminen, Kai Savolainen, Laura K. Schnackenberg, D.T. Selvam, Praveen Sharma, Qiang Shi, Elina Sieppi, Jon Sobus, Miguel A. Sogorb, Melissa Stick, Markus Storvik, David T. Szabo, Yu-Mei Tan, João S. Teodoro, Rogelio Tornero-Velez, Beáta Toth, Aristides M. Tsatsakis, Kirsi Vähäkangas, Deon van der Merwe, Ana T. Varela, Eugenio Vilanova, Suryanarayana V. Vulimiri, Kevin D. Welch, Xi Yang, Snjezana Zaja-Milatovic, Csaba K. Zoltani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e252fcbbe40cb0fd666a060a268dd861
https://doi.org/10.1016/b978-0-12-404630-6.00070-1

Parameters for Pesticide QSAR and PBPK/PD Models for Human Risk Assessment

Autor: James B. Knaak, Charles Timchalk, Rogelio Tornero-Velez, M. R. Goldsmith, J. C. Johnson, D. T. Chang, R. Tornero-Velez, J. B. Knaak, Curtis C. Dary, Robert W. Gerlach, Masahiko Okamoto, Hideo Kaneko, J. V. Bruckner, T. G. Osmitiz, S. Anand, D. Minnema, W. Schmitt, N. Assaf, J. Zastre, Mai A. Ngo, Howard I. Maibach, William G. Reifenrath, Ernest Hodgson, Andrew D. Wallace, Clement E. Furlong, Rebecca J. Richter, Lucio G. Costa, Gail P. Jarvik, Matthew K. Ross, Mariola J. Edelmann, Virginia C. Moser, Janice E. Chambers, Edward C. Meek, Howard W. Chambers, Jordan Ned Smith, Andrea Hjerpe, Torka S. Poet, Sookwang Lee, David M. Soderlund, Michael F. Hughes, Melissa P. L. Chan, James M. Starr, Timothy J. Shafer, Edward J. Scollon, Michael J. DeVito, Daniel T. Chang, Michael-Rock Goldsmith, Yu-Mei Tan, Christopher M. Grulke, Ling-Jen Chen, Elin M. Ulrich, Andrew B. Lindstrom, Melissa A. Pasquinelli, James R. Rabinowitz, Christopher D. Ruark, C. Eric Hack, Peter J. Robinson, Jeffery M. Gearhart, Jimena L. Davis, R. Woodrow Setzer, Corie A. Ellison, Robi