Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Curtis Braun"'
Publikováno v:
Biochemistry. 35:5458-5463
Glycogen-debranching enzyme catalyzes the removal of branching from glycogen via a two-step process involving first the transfer of a maltotriosyl unit from the branch to the main chain and second the hydrolysis of the residual alpha-(1,6)-linked glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a539ab212842c6de2cda9a5383337f8
https://doi.org/10.1021/bi9526488
https://doi.org/10.1021/bi9526488
Publikováno v:
Journal of Biological Chemistry. 270:26778-26781
2-Deoxy-2,2-difluoroglycosides are a new class of mechanism-based inhibitors of alpha-glycosidases, which function via the accumulation of a stable difluoroglycosyl-enzyme intermediate. Two members of this new class of inhibitor have been synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f31a161d388e7a8b88de775a1576e91c
https://doi.org/10.1074/jbc.270.45.26778
https://doi.org/10.1074/jbc.270.45.26778
Autor:
Curtis Braun, Stephen G. Withers
Publikováno v:
Carbohydrate Research. 271:113-118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb870e50dc78c5f369b3981257e6115
https://doi.org/10.1016/0008-6215(95)00020-t
https://doi.org/10.1016/0008-6215(95)00020-t
Publikováno v:
Carbohydrate Research. 268:93-106
4′-Deoxy-α-maltosyl fluoride and 4″-deoxy-α-maltotriosyl fluoride were synthesized to serve as mechanistic probes for α-glucanotransferases such as the glycogen debranching enzyme. The deoxy derivatives were prepared starting from maltose and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d46a3be09038714765d10d933af2fb5
https://doi.org/10.1016/0008-6215(94)00317-9
https://doi.org/10.1016/0008-6215(94)00317-9
Publikováno v:
Enzyme and Microbial Technology. 14:90-95
Cooperativitiy between different, purified hemicelluloytic enzymes was examined using as substrates two lignin-carbohydrate complexes isolated from the water-soluble fractions of steam/aqueous thermo-mechanical treatment of Populus deltoides wood. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92d05557c32ea80a3fdcf065db3f452b
https://doi.org/10.1016/0141-0229(92)90163-i
https://doi.org/10.1016/0141-0229(92)90163-i
Publikováno v:
Biochemistry. 30:1419-1424
The amylo-1,6-glucosidase catalytic activity of glycogen debranching enzyme allows it to hydrolyze alpha-D-glucosyl fluoride, in the absence or presence of glycogen or oligosaccharides, releasing equal amounts of fluoride and glucose at rates compara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4642e92914b5d101b564620727341c
https://doi.org/10.1021/bi00219a036
https://doi.org/10.1021/bi00219a036
Publikováno v:
The Journal of organic chemistry. 73(8)
The synthesis of a series of 2-deoxy-2,2-dihaloglycosyl halides as potential alpha-glycosidase inactivators has been achieved via the halogenation of protected 2-fluoroglycal precursors. Direct chlorination of per-O-acetylated 2-fluoro-d-glucal and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce80a526cefed9bb62b32a3de8ef5dc0
https://pubmed.ncbi.nlm.nih.gov/18345685
https://pubmed.ncbi.nlm.nih.gov/18345685
Autor:
Yili Wang, Stephen G. Withers, Gary D. Brayer, Christopher M. Overall, Curtis Braun, Robert Maurus, Gary Sidhu, Edwin H. Rydberg, Nham T. Nguyen
Publikováno v:
Biochemistry. 39(16)
We report a multifaceted study of the active site region of human pancreatic alpha-amylase. Through a series of novel kinetic analyses using malto-oligosaccharides and malto-oligosaccharyl fluorides, an overall cleavage action pattern for this enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::330bceef111c41d0bad17a035702a488
https://pubmed.ncbi.nlm.nih.gov/10769135
https://pubmed.ncbi.nlm.nih.gov/10769135
Autor:
John D. McCarter, Curtis Braun, Yung-Feng Liao, Kelley W. Moremen, Stephen G. Withers, Steven Howard
Publikováno v:
Biochemical and biophysical research communications. 238(3)
The stereochemical course of the hydrolyses catalysed by two alpha-mannosidases has been determined directly by 1H NMR. Synthetic substrates were incubated with the enzymes and the anomeric configuration of the initially formed product was ascertaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010d3b6d85cf26c3657fd340c50102e6
https://pubmed.ncbi.nlm.nih.gov/9325188
https://pubmed.ncbi.nlm.nih.gov/9325188
Publikováno v:
ACS Symposium Series ISBN: 9780841234420
Biomedical Frontiers of Fluorine Chemistry
Biomedical Frontiers of Fluorine Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56a3c5f8f5dc50d3f64c255b9bc10186
https://doi.org/10.1021/bk-1996-0639.ch020
https://doi.org/10.1021/bk-1996-0639.ch020
