Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Curtis A. Chin"'
Autor:
Hon S. Leong, Amy E. Robertson, Konstantin Stoletov, Sean J. Leith, Curtis A. Chin, Andrew E. Chien, M. Nicole Hague, Amber Ablack, Katia Carmine-Simmen, Victor A. McPherson, Carl O. Postenka, Eva A. Turley, Sara A. Courtneidge, Ann F. Chambers, John D. Lewis
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1558-1570 (2014)
Tumor cell extravasation is a key step during cancer metastasis, yet the precise mechanisms that regulate this dynamic process are unclear. We utilized a high-resolution time-lapse intravital imaging approach to visualize the dynamics of cancer cell
Externí odkaz:
https://doaj.org/article/8c78d3b31e9a449eb0c66822ac1f735e
Autor:
Jose A. Karam, Pavlos Msaouel, Cara L. Haymaker, Surena F. Matin, Matthew T. Campbell, Amado J. Zurita, Amishi Y. Shah, Ignacio I. Wistuba, Enrica Marmonti, Dzifa Y. Duose, Edwin R. Parra, Luisa Maren Solis Soto, Caddie Laberiano-Fernandez, Marisa Lozano, Alice Abraham, Max Hallin, Curtis D. Chin, Peter Olson, Hirak Der-Torossian, Xiaohong Yan, Nizar M. Tannir, Christopher G. Wood
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Sitravatinib is an immunomodulatory tyrosine kinase inhibitor that can augment responses when combined with programmed death-1 inhibitors such as nivolumab. We report a single-arm, interventional, phase 2 study of neoadjuvant sitravatinib in
Externí odkaz:
https://doaj.org/article/8affada371c5430f97f977800c38a734
Autor:
Shu Yu Grace Wang, Elizabeth Rao, Jianyu Rao, Josephine Aguilar-Jakthong, Christine Chow, Curtis D Chin, Weibo Yu, Yunfeng Li
Publikováno v:
Acta Cytologica. 65:348-353
Introduction: Multiplex biomarker analysis of cytological body fluid specimens is often used to assist cytologists in distiguishing metastatic cancer cells from reactive mesothelial cells. However, evaluating biomarker expression visually may be chal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88642670ac395f4748df0f1554a318bd
https://doi.org/10.1159/000515976
https://doi.org/10.1159/000515976
Autor:
Curtis D Chin, I. P. Shintaku, Jianyu Rao, Hsiao-Wang Chen, Gottfried E. Konecny, Charlene M. Fares, Maira P. Campos
Publikováno v:
Modern Pathology. 33:2001-2010
Identifying patients who respond to immune checkpoint blockade (ICB) is a significant challenge in oncology. While PD-L1 expression by immunohistochemistry (IHC) is the current diagnostic gold standard for patient selection, it nevertheless does not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c71562f9ca02068514b0bd53629ca3f
https://doi.org/10.1038/s41379-020-0567-3
https://doi.org/10.1038/s41379-020-0567-3
Publikováno v:
The Journal of Applied Laboratory Medicine. 3:1054-1058
A 61-year-old woman was evaluated at our institution for enrollment in a clinical trial for relapsed/refractory multiple myeloma. The initial eligibility evaluation revealed an increased total bilirubin result of 7.2 mg/dL [123.1 μmol/L; reference i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f85a4ba9e17a3571a0315b69e4deb26
https://doi.org/10.1373/jalm.2018.026575
https://doi.org/10.1373/jalm.2018.026575
Publikováno v:
Current opinion in obstetricsgynecology. 32(1)
Purpose of review Immune checkpoint blockade (ICB) is a promising area of cancer therapeutic research. Therapies targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) mechanism of tumor immune evasion have resulted in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71b437313288e0f528f2c005ecb4b8f
https://pubmed.ncbi.nlm.nih.gov/31804230
https://pubmed.ncbi.nlm.nih.gov/31804230
Autor:
David Steinmiller, Yuk Kee Cheung, Robert Rouse, Ruben Sahabo, Curtis D. Chin, Janneke van de Wijgert, Etienne Karita, Vincent Linder, Jessica Justman, Sarah L. Braunstein, Tassaneewan Laksanasopin, Hesam Parsa, Hannah Moore, Lambert Mwambarangwe, Jennifer Wang, Wafaa El-Sadr, Gisele Umviligihozo, Samuel K. Sia
Publikováno v:
Nature medicine, 17(8), 1015-1019. Nature Publishing Group
One of the great challenges in science and engineering today is to develop technologies to improve the health of people in the poorest regions of the world. Here we integrated new procedures for manufacturing, fluid handling and signal detection in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8a845545628be140f4082915472111
https://doi.org/10.1038/nm.2408
https://doi.org/10.1038/nm.2408
Publikováno v:
Biomedical Microdevices. 10:459-467
An important element of artificial skin is a tissue scaffold that allows for fast host regeneration. We present a microfabrication strategy, based on gelling collagen-based components inside a microfluidic device, that produces well-controlled pore s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023ccfcd6e139f3b5575a68e1ad8c079
https://doi.org/10.1007/s10544-007-9155-2
https://doi.org/10.1007/s10544-007-9155-2
Publikováno v:
Lab Chip. 7:41-57
A rapidly emerging field in lab-on-a-chip (LOC) research is the development of devices to improve the health of people in developing countries. In this review, we identify diseases that are most in need of new health technologies, discuss special des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d353d41442ddabb74793b3193457f8
https://doi.org/10.1039/b611455e
https://doi.org/10.1039/b611455e
Autor:
Curtis D. Chin, Robert Langer, Omid C. Farokhzad, George Eng, Jianjun Cheng, Alice Kiselyuk, Benjamin A. Teply, Aurelia Hermmann, Sangyong Jon, Ali Khademhosseini
Publikováno v:
Analytical Chemistry. 77:5453-5459
Nanoparticles and microparticles have many potential biomedical applications ranging from imaging to drug delivery. Therefore, in vitro systems that can analyze and optimize the interaction of such particles with cells may be beneficial. Here, we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cdba7c7e5969e5ee2a2e025686c4379
https://doi.org/10.1021/ac050312q
https://doi.org/10.1021/ac050312q