Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Curt Wittenberg"'
Autor:
Michelle V Wagner, Marcus B Smolka, Rob A M de Bruin, Huilin Zhou, Curt Wittenberg, Steven F Dowdy
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4300 (2009)
The Whi5 transcriptional repressor is a negative regulator of G1 cell cycle progression in Saccharomyces cerevisiae and is functionally equivalent to the Retinoblastoma (Rb) tumor suppressor protein in mammals. In early G1, Whi5 binds to and inhibits
Externí odkaz:
https://doaj.org/article/91f47ffab85c4cb5a6a1668e3bab7c94
Autor:
Julia M. Gauglitz, Kiana A. West, Wout Bittremieux, Candace L. Williams, Kelly C. Weldon, Morgan Panitchpakdi, Francesca Di Ottavio, Christine M. Aceves, Elizabeth Brown, Nicole C. Sikora, Alan K. Jarmusch, Cameron Martino, Anupriya Tripathi, Michael J. Meehan, Kathleen Dorrestein, Justin P. Shaffer, Roxana Coras, Fernando Vargas, Lindsay DeRight Goldasich, Tara Schwartz, MacKenzie Bryant, Gregory Humphrey, Abigail J. Johnson, Katharina Spengler, Pedro Belda-Ferre, Edgar Diaz, Daniel McDonald, Qiyun Zhu, Emmanuel O. Elijah, Mingxun Wang, Clarisse Marotz, Kate E. Sprecher, Daniela Vargas-Robles, Dana Withrow, Gail Ackermann, Lourdes Herrera, Barry J. Bradford, Lucas Maciel Mauriz Marques, Juliano Geraldo Amaral, Rodrigo Moreira Silva, Flavio Protasio Veras, Thiago Mattar Cunha, Rene Donizeti Ribeiro Oliveira, Paulo Louzada-Junior, Robert H. Mills, Paulina K. Piotrowski, Stephanie L. Servetas, Sandra M. Da Silva, Christina M. Jones, Nancy J. Lin, Katrice A. Lippa, Scott A. Jackson, Rima Kaddurah Daouk, Douglas Galasko, Parambir S. Dulai, Tatyana I. Kalashnikova, Curt Wittenberg, Robert Terkeltaub, Megan M. Doty, Jae H. Kim, Kyung E. Rhee, Julia Beauchamp-Walters, Kenneth P. Wright, Maria Gloria Dominguez-Bello, Mark Manary, Michelli F. Oliveira, Brigid S. Boland, Norberto Peporine Lopes, Monica Guma, Austin D. Swafford, Rachel J. Dutton, Rob Knight, Pieter C. Dorrestein
Publikováno v:
Nature biotechnology, vol 40, iss 12
Nat Biotechnol
Nat Biotechnol
Human untargeted metabolomics studies annotate only ~10% of molecular features. We introduce reference-data-driven analysis to match metabolomics tandem mass spectrometry (MS/MS) data against metadata-annotated source data as a pseudo-MS/MS reference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadcc5a8ebaed4c919d942163887bc61
https://doi.org/10.1038/s41587-022-01368-1
https://doi.org/10.1038/s41587-022-01368-1
Autor:
Rodrigo Moreira da Silva, Tara Schwartz, Juliano Geraldo Amaral, Thiago M. Cunha, Scott Jackson, MacKenzie Bryant, Francesca Diottavio, Robert H. Mills, Norberto Peporine Lopes, Robert Terkeltaub, Katrice Lippa, Brigid S. Boland, Christina Jones, Pieter C. Dorrestein, Morgan Panitchpakdi, Mingxun Wang, Megan M. Doty, Christine M. Aceves, Candace L. Williams, Fernando Vargas, Monica Guma, Michael J. Meehan, Lucas Miranda Marques, Renê Donizeti Ribeiro de Oliveira, Rachel J. Dutton, Stephanie Servetas, Nancy Lin, Qiyun Zhu, Paulo Louzada-Junior, Jae H. Kim, Edgar Diaz, Douglas Galasko, Austin D. Swafford, Maria Gloria Dominguez-Bello, Nicole Sikora, Paulina Piotrowski, Wout Bittremieux, Abigail J. Johnson, Cameron Martino, Clarisse Marotz, Rob Knight, Lourdes Herrera, Michelli F. Oliveira, Kate E. Sprecher, Rima Kaddurah Daouk, Elijah Emmanuel, Dana Withrow, Tatyana Kalashnikova, Curt Wittenberg, Kiana West, Pedro Belda-Ferre, Alan K. Jarmusch, Daniela Vargas Robles, Mark Manery, Barry J. Bradford, Kathleen Dorrestein, Flávio Protaso Veras, Kenneth P. Wright, Gail Ackermann, Greg Humphrey, Daniel McDonald, Lindsay DeRight Goldasich, Anupriya Tripathi, Sandra DaSilva, Julia Gauglitz, David Gonzalez, Roxana Coras, Elizabeth Brown, Kyung E. Rhee, Katharina Spengler, Parambir S. Dulai, Julia Beauchamp-Walters, Kelly C. Weldon, Justin P. Shaffer
Human untargeted metabolomics studies succeed in annotating only ~10% of molecular features. We, therefore, introduce reference data-driven analysis that uses the source data as a pseudo-MS/MS reference library to match against human metabolomics MS/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9f8b9788cae579d9220939f069d2709
https://doi.org/10.21203/rs.3.rs-654519/v1
https://doi.org/10.21203/rs.3.rs-654519/v1
Autor:
Dominic S. Nguyen, Wout Bittremieux, Rodrigo Moreira da Silva, Juliano Geraldo Amaral, Jae H. Kim, Lucas Miranda Marques, Rob Knight, Christine M. Aceves, Monica Guma, Gregory Humphrey, Morgan Panitchpakdi, Pieter C. Dorrestein, Julia Beauchamp-Walters, Daniel McDonald, Douglas Galasko, Thiago M. Cunha, Nicole Sikora, Qiyun Zhu, Candace L. Williams, Mark J. Manary, Austin D. Swafford, Pedro Belda-Ferre, Robert H. Mills, Alan K. Jarmusch, Lourdes Herrera, Flávio Protaso Veras, Parambir S. Dulai, Francesca Di Ottavio, Fernando Vargas, Abigail J. Johnson, Michelli F. Oliveira, Kelly C. Weldon, Justin P. Shaffer, Paulo Louzada-Junior, Renê Donizeti Ribeiro de Oliveira, Erfan Sayyari, MacKenzie Bryant, Julia M. Gauglitz, Anupriya Tripathi, David Gonzalez, Maria Gloria Dominguez-Bello, Kyung E. Rhee, Daniela Vargas Robles, Katharina Spengler, Norberto Peporine Lopes, Kenneth P. Wright, Robert Terkeltaub, Emmanuel O. Elijah, Rachel J. Dutton, Megan M. Doty, Clarisse Marotz, Dana Withrow, Brigid S. Boland, Curt Wittenberg, Tara Schwartz, Edgar Diaz, Cameron Martino, Lindsay DeRight Goldasich, Kate E. Sprecher, Roxana Coras, Elizabeth Brown, Barry J. Bradford, Gail Ackermann, Mingxun Wang
SummaryThe human metabolome has remained largely unknown, with most studies annotating ∼10% of features. In nucleic acid sequencing, annotating transcripts by source has proven essential for understanding gene function. Here we generalize this conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d75498d82cefe93b03c3a2591989835
https://doi.org/10.1101/2020.07.08.194159
https://doi.org/10.1101/2020.07.08.194159
Autor:
Paulo Louzada-Junior, Norberto Peporine Lopes, Robert Terkeltaub, Megan M. Doty, Kyung E. Rhee, Katharina Spengler, Flávio Protaso Veras, Fernando Vargas, Renê Donizeti Ribeiro de Oliveira, Erfan Sayyari, Christine M. Aceves, Daniela Vargas-Robles, Dominic S. Nguyen, Francesca Di Ottavio, Monica Guma, Thiago M. Cunha, Gail Ackermann, Rodrigo Moreira da Silva, Abigail J. Johnson, Lucas Miranda Marques, Douglas Galasko, Michelli F. Oliveira, Nicole Sikora, Gregory Humphrey, Mark J. Manary, Austin D. Swafford, Tara Schwartz, Pedro Belda-Ferre, Candace L. Williams, Robert H. Mills, Mingxun Wang, Daniel McDonald, Alan K. Jarmusch, Pieter C. Dorrestein, Juliano Geraldo Amaral, Wout Bittremieux, Kelly C. Weldon, Justin P. Shaffer, Kate E. Sprecher, Emmanuel O. Elijah, Julia Beauchamp-Walters, Rachel J. Dutton, Kenneth P. Wright, Qiyun Zhu, Rob Knight, Lindsay DeRight Goldasich, Lourdes Herrera, Clarisse Marotz, Dana Withrow, MacKenzie Bryant, Julia M. Gauglitz, Curt Wittenberg, Morgan Panitchpakdi, Brigid S. Boland, Parambir S. Dulai, Maria Gloria Dominguez Bello, Anupriya Tripathi, David Gonzalez, Edgar Diaz, Cameron Martino, Barry J. Bradford, Roxana Coras, Elizabeth Brown, Jae H. Kim
Publikováno v:
SSRN Electronic Journal.
The human metabolome has remained largely unknown, with most studies annotating ~10% of features. In nucleic acid sequencing, annotating transcripts by source has proven essential for understanding gene function. Here we generalize this concept to st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd185c61c9a3400f406a450e03911123
https://doi.org/10.2139/ssrn.3661950
https://doi.org/10.2139/ssrn.3661950
Autor:
Charly Chahwan, David E. Lee, Curt Wittenberg, Tatyana I. Kalashnikova, Noel F. Lowndes, Anna Travesa, Robertus A.M. de Bruin, Sarah Rose Cass
Publikováno v:
Molecular and cellular biology. 37(16)
In Saccharomyces cerevisiae, G1/S transcription factors MBF and SBF regulate a large family of genes important for entry to the cell cycle and DNA replication and repair. Their regulation is crucial for cell viability, and it is conserved throughout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84ef3ae92c685d046115f7f4b814e53
https://pubmed.ncbi.nlm.nih.gov/23382076
https://pubmed.ncbi.nlm.nih.gov/23382076
Autor:
Curt Wittenberg, Steven B. Haase
Publikováno v:
Genetics. 196:65-90
Nearly 20% of the budding yeast genome is transcribed periodically during the cell division cycle. The precise temporal execution of this large transcriptional program is controlled by a large interacting network of transcriptional regulators, kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915f50f7df8b4404cb02ca5efa31d735
https://doi.org/10.1534/genetics.113.152595
https://doi.org/10.1534/genetics.113.152595
Publikováno v:
Current Biology. 23:1629-1637
Summary Background In eukaryotic cells, detection of replication stress results in the activation of the DNA replication checkpoint, a signaling cascade whose central players are the kinases ATR and Chk1. The checkpoint response prevents the accumula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c467bac77527969fa0eabe024d6d55
https://doi.org/10.1016/j.cub.2013.06.063
https://doi.org/10.1016/j.cub.2013.06.063
Autor:
Curt Wittenberg
Publikováno v:
Cell Cycle. 9:3842-3847
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8eb2be7ec451b192f61cb6dc49f79286
https://doi.org/10.4161/cc.9.19.13380
https://doi.org/10.4161/cc.9.19.13380
Publikováno v:
Cell Cycle. 8:214-217
The DNA replication and DNA damage checkpoints are required for the efficient response to genotoxic stress, which is critical for genome stability and cell survival. The DNA replication and damage checkpoints delay progression into mitosis, and at th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da8fefe3c2c77db2cca05d9a175c4a71
https://doi.org/10.4161/cc.8.2.7412
https://doi.org/10.4161/cc.8.2.7412