Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Curt Dale Haffner"'
Autor:
Martha Triantafilou, Seth L. Masters, Robert G. Ferris, Louise K. Modis, Magdalena Czubala, Kathy Triantafilou, Christopher J. K. Ward, Emma Koppe, Curt Dale Haffner, Vipulkumar Kantibhai Patel, Heather Amrine-Madsen, Vincent Piguet
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 4, p e1009417 (2021)
PLoS Pathogens, Vol 17, Iss 4, p e1009417 (2021)
Macrophages are important drivers of pathogenesis and progression to AIDS in HIV infection. The virus in the later phases of the infection is often predominantly macrophage-tropic and this tropism contributes to a chronic inflammatory and immune acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db110e44ba2fb7ba2b06a3325be12d86
https://pubmed.ncbi.nlm.nih.gov/33861800
https://pubmed.ncbi.nlm.nih.gov/33861800
Autor:
Arthur Shu, Yiqian Lian, Huijie Li, Curt Dale Haffner, Terry Vincent Hughes, Ami S. Lakdawala, Julie A. Cox, Pamela A. Haile, Constantine Kreatsoulas, Beth Anne Knapp-Reed, Lisa M. Shewchuk, David B. Lipshutz, John F. Mehlmann, Michael T. Ouellette, Christopher J Aquino, Mark Elban, Nicole Cathleen Goodwin, Huiqiang Zhou, Adam Kenneth Charnley, Bartholomew J. Votta, Robert W. Marquis, Joseph J. Romano, Linda N. Casillas, Peter J. Gough, Máire A. Convery, John Bertin
Publikováno v:
ACS Med Chem Lett
[Image: see text] Herein we report the discovery of pyrazolocarboxamides as novel, potent, and kinase selective inhibitors of receptor interacting protein 2 kinase (RIP2). Fragment based screening and design principles led to the identification of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdf5d01bc977b3b388a3da2de569f9a2
https://pubmed.ncbi.nlm.nih.gov/31749904
https://pubmed.ncbi.nlm.nih.gov/31749904
Autor:
James E. Long, J. Darren Stuart, Timothy K. Tippin, Marcia L. Moss, Dallas K. Croom, Michael K. James, Stephen V. Frye, Frank W. Lee, D. Mark Bickett, Kenneth William Batchelor, Curt Dale Haffner, John Van Arnold, George F. Dorsey, Patrick R. Maloney, Rayomand J. Unwalla, Stephanie L. Schweiker, Roger N. Hiner, H. Neal Bramson, Gaochoa Tian, Mary K. Grizzle, Robert A. Noe
Publikováno v:
Journal of medicinal chemistry. 38(14)
A variety of C17 amide-substituted 6-azaandrost-4-en-3-ones were prepared and tested versus human type 1 and 2 steroid 5 alpha-reductase (5AR) and human adrenal 3 beta-hydroxy-delta 5-steroid dehydrogenase/3-keto-delta 5-steroid isomerase (3BHSD) in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c1d5384a6b9ff9710bf6af13c6b600
https://pubmed.ncbi.nlm.nih.gov/7629802
https://pubmed.ncbi.nlm.nih.gov/7629802