Antivirals for influenza-like illness? A randomized Controlled trial of Clinical and Cost effectiveness in primary CarE (ALIC4E): The ALIC4E Protocol

Autor: Frederico Martinón-Torres, Jane Holmes, Maciek Godycki-Cwirko, Dionyssios Varthalis, Theo J M Verheij, Ruta Radzeviciene-Jurgute, Emily Bongard, Pia Touboul, Alike W van der Velden, Philippe Beutels, Margareta Ieven, Ana Moragas, Johanna Cook, Antoni Torres, An De Sutter, Nick A Francis, Pär-Daniel Sundvall, Paul Little, Herman Goossens, Morten Lindbæk, Annelies Colliers, Rune Aabenhus, József Pauer, Muireann De Paor, Dominik Glinz, Christopher C Butler, Curt Brugman, Sławomir Chlabicz, Menno de Jong, Melanie J. Davies, Ben Saville, Samuel Coenen, Markéta Pfeiferová

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
BMJ open
BMJ open, 8(7). BMJ Publishing Group
BMJ Open
Recercat. Dipósit de la Recerca de Catalunya
Bongard, E, van der Velden, A W, Cook, J, Saville, B, Beutels, P, Aabenhus, R M, Brugman, C, Chlabicz, S, Coenen, S, Colliers, A, Davies, M, De Paor, M, De Sutter, A, Francis, N A, Glinz, D, Godycki-cwirko, M, Goossens, H, Holmes, J, Ieven, M, de Jong, M, Lindbaek, M, Little, P, Martinon-Torres, F, Moragas, A, Pauer, J, Pfeiferova, M, Radzeviciene-Jurgute, R, Sundvall, P-D, Torres, A, Touboul, P, Varthalis, D, Verheij, T & Butler, C C 2018, ' Antivirals for influenza-Like Illness? A randomised Controlled trial of Clinical and Cost effectiveness in primary CarE (ALIC 4 E) : the ALIC 4 E protocol ', BMJ Open, vol. 8, no. 7, e021032 . https://doi.org/10.1136/bmjopen-2017-021032

IntroductionEffective management of seasonal and pandemic influenza is a high priority internationally. Guidelines in many countries recommend antiviral treatment for older people and individuals with comorbidity at increased risk of complications. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436cc18eaa71989a3bf682536af06aa7
http://ora.ox.ac.uk/objects/uuid:

Clinicians' interpretations of point of care urine culture versus laboratory culture results: analysis from the four-country POETIC trial of diagnosis of uncomplicated urinary tract infection in primary care

Autor: Carl Llor, Mandy Wootton, Paul Little, Timothy Pickles, Curt Brugman, Saskia Hullegie, Kerenza Hood, Nigel Kirby, Emma Thomas-Jones, David Gillespie, Micaela Gal, Nick A Francis, Christopher C Butler, Theo Verheij, Janine Bates, Michael Moore

Publikováno v: Family Practice, 34(4), 392. Oxford University Press

Background Urine culture at the point of care minimises delay between obtaining the sample and agar inoculation in a microbiology laboratory, and quantification and sensitivity results can be available more rapidly in primary care. Objective To ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf232bd397564b3bc199a58b4587a250

Metagenomic analysis of a sample from a patient with respiratory tract infection reveals the presence of a γ-papillomavirus

Autor: Seyed Mohammad Jazaeri Farsani, Martin Deijs, Theo J M Verheij, Christine Lammens, Saskia van Vugt, Lia van der Hoek, Margareta Ieven, Curt Brugman, Marta Canuti, Maarten F. Jebbink, Herman Goossens, Melle Holwerda, Michel de Vries, Katherine Loens

Publikováno v: Frontiers in Microbiology
Frontiers in Microbiology, Vol 5 (2014)
Frontiers in microbiology
Frontiers in microbiology, 5. Frontiers Media S.A.

Previously unknown or unexpected pathogens may be responsible for that proportion of respiratory diseases in which a causative agent cannot be identified. The application of broad-spectrum, sequence independent virus discovery techniques may be usefu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66077295f32f0f7bd420650379f6f9ae

Rapid assessment of protein-tyrosine phosphatase expression levels by RT-PCR with degenerate primers

Autor: Curt Brugman, Bé Wieringa, Jan Schepens, Wiljan Hendriks

Publikováno v: Molecular Biology Reports. 19:105-108

Using degenerate oligodeoxynucleotide primers we previously obtained cDNA fragments from ten different murine protein-tyrosine phosphatases (PTPases). Employing this same primer set, a method was developed to assess the expression levels of these PTP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d768c345204e6d3744438df356fccf62
https://doi.org/10.1007/bf00997155