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Autor:
Curran Landry, Lidiya Stavitskaya, Alexander Sedykh, Kevin P. Cross, Jae Wook Yoo, Naomi L. Kruhlak
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 113
All drugs entering clinical trials are expected to undergo a series of in vitro and in vivo genotoxicity tests as outlined in the International Council on Harmonization (ICH) S2 (R1) guidance. Among the standard battery of genotoxicity tests used for