Reserva Ovárica: Avaliação, Utilidade Clínica e o Impacto da Contraceção Hormonal

Autor: Filipa Braz da Cruz Faria Curinha

Externí odkaz: https://hdl.handle.net/10216/134581

Centriole structural integrity defects are a crucial feature of Hydrolethalus Syndrome.

Autor: Curinha A; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Huang Z; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Anglen T; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Strong MA; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Gliech CR; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Jewett CE; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Friskes A; Division of Cell Biology, Oncode Institute, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Holland AJ; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 06. Date of Electronic Publication: 2024 Mar 06.

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PIDDosome-induced p53-dependent ploidy restriction facilitates hepatocarcinogenesis

Autor: Laura Bongiovanni, Kaoru Tsuchia, Tatjana Stojakovic, Katja Knapp, Vincent Zoran Braun, Hubert Scharnagl, Nataliya Rohr-Udilova, Georg Semmler, Floris Foijer, Gerald Timelthaler, Andreas Villunger, Matthias Pinter, Alain de Bruin, Tamas G. Szabo, Diana C.J. Spierings, Bart Westendorp, Valentina C. Sladky, Thomas Reiberger, Ana Curinha, Hilda van den Bos

Publikováno v: EMBO Rep
EMBO Reports, 21, 1. Nature Publishing Group
EMBO Reports
EMBO reports
Embo Reports, 21(12):50893. Wiley

Polyploidization frequently precedes tumorigenesis but also occurs during normal development in several tissues. Hepatocyte ploidy is controlled by the PIDDosome during development and regeneration. This multi‐protein complex is activated by supern

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ed81958c6c6004226d70c82a580bd4f
https://doi.org/10.15252/embr.202050893

PIDDosome‐induced p53‐dependent ploidy restriction facilitates hepatocarcinogenesis.

Autor: Sladky, Valentina C, Knapp, Katja, Szabo, Tamas G, Braun, Vincent Z, Bongiovanni, Laura, Bos, Hilda, Spierings, Diana CJ, Westendorp, Bart, Curinha, Ana, Stojakovic, Tatjana, Scharnagl, Hubert, Timelthaler, Gerald, Tsuchia, Kaoru, Pinter, Matthias, Semmler, Georg, Foijer, Floris, Bruin, Alain, Reiberger, Thomas, Rohr‐Udilova, Nataliya, Villunger, Andreas

Publikováno v: EMBO Reports; 12/3/2020, Vol. 21 Issue 12, p1-16, 16p