Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Cunzhen Zhang"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Hepatocellular carcinoma (HCC) is an extremely malignant tumor that affects individuals throughout the world. One of the main causes of HCC is hepatitis B virus (HBV). Therefore, it is crucial to understand the mechanisms underlying HBV carcinogenesi
Externí odkaz:
https://doaj.org/article/908e4beb8f16481297647cfab985f2af
Autor:
Guiming Hu, Yan Fang, Haiwei Xu, Guanzhe Wang, Rui Yang, Fei Gao, Qingda Wei, Yuhan Gu, Cunzhen Zhang, Jinhuan Qiu, Na Gao, Qiang Wen, Hailing Qiao
Publikováno v:
Advanced Science, Vol 10, Iss 23, Pp n/a-n/a (2023)
Abstract Glioblastoma (GBM) is a devastating inflammation‐related cancer for which novel therapeutic targets are urgently required. Previous studies of the authors indicate Cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target and develop a s
Externí odkaz:
https://doaj.org/article/45ceece0b8b84ef49ef63ca45f768716
Autor:
Yan Fang, Hongming Yang, Guiming Hu, Jiakun Lu, Jun Zhou, Na Gao, Yuhan Gu, Cunzhen Zhang, Jinhuan Qiu, Yuanyuan Guo, Yunfei Zhang, Qiang Wen, Hailing Qiao
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract The effect of the cytochrome P450 oxidoreductase (POR) rs10954732 (G > A) polymorphism on hepatocellular carcinoma (HCC) susceptibility is unknown. Here we found that A allele carriers showed a 69% decrease in susceptibility to HCC with over
Externí odkaz:
https://doaj.org/article/2033194e2c7449e9a707cddc596dcd12
Autor:
Guiming Hu, Fei Gao, Guanzhe Wang, Yan Fang, Yuanyuan Guo, Jun Zhou, Yuhan Gu, Cunzhen Zhang, Na Gao, Qiang Wen, Hailing Qiao
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background Although an association between the cytochrome P4502D6 (CYP2D6) *10 (100C>T) polymorphism and hepatocellular carcinoma (HCC) is known, the mechanism remains unclear. Here we aimed to explore mechanisms of CYP2D6*10 (100C>T) polymo
Externí odkaz:
https://doaj.org/article/e6c8dd113c44480a88dbd9e2659a0bd1
Autor:
Shuang Feng, Zhiwen Ding, Jin Wang, Ziliang Qian, Shanshan Li, Cunzhen Zhang, Haibei Xin, Shupeng Liu, Guanghui Ding, Minggen Hu, Yan Meng, Nan Li
Publikováno v:
Cancer Medicine, Vol 9, Iss 14, Pp 5075-5085 (2020)
Abstract Purpose To characterize plasma cell‐free cancer genome chromosomal instabilities (CIN) in patients with liver cancer and to evaluate the potential of CIN as minimally invasive biomarkers for primary liver cancer (PLC) diagnoses. Experiment
Externí odkaz:
https://doaj.org/article/8f692d3aa88442c6acf45398c4b5d84f
Autor:
Cunzhen Zhang, Lei Lu, Haibei Xin, Minfeng Zhang, Zhiwen Ding, Qiaomei Li, Kuang Chen, Minggen Hu, Shupeng Liu, Nan Li
Publikováno v:
Journal of Oncology. 2022:1-11
Hepatitis B virus (HBV) is one of the major risk factors for HCC (hepatocellular carcinoma) occurrence with a diverse role in the pathogenesis of HCC. More works need to be performed to elucidate a more thorough understanding of the molecular mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90dc7b965e293aa8aef01584362c7ec
https://doi.org/10.1155/2022/9034105
https://doi.org/10.1155/2022/9034105
Autor:
Yuan-Yuan Guo, Cunzhen Zhang, Jun Zhou, Yuhan Gu, Fei Gao, Hai-Ling Qiao, Guanzhe Wang, Guiming Hu, Qiang Wen, Yan Fang, Na Gao
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background Although an association between the cytochrome P4502D6 (CYP2D6) *10 (100C>T) polymorphism and hepatocellular carcinoma (HCC) is known, the mechanism remains unclear. Here we aimed to explore mechanisms of CYP2D6*10 (100C>T) polymorphism co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eab0d2f166f1513e4ff9c1aaf24d8ef
https://doaj.org/article/e6c8dd113c44480a88dbd9e2659a0bd1
https://doaj.org/article/e6c8dd113c44480a88dbd9e2659a0bd1
Autor:
Wei Zhou, Shupeng Liu, Dandan Liang, Haibei Xin, Wenbo Han, Minfeng Zhang, Dandan Ren, Shanshan Li, Zhiwen Ding, Cunzhen Zhang, Lihong Wu, Guanghui Ding, Hongli Luo, Nan Li, Yanhui Chen, Huan Chen, Henghui Zhang, Hao Zhang, Yating Wang
Publikováno v:
HPB. 23:1061-1071
Background Tumor microenvironment plays an essential role during the progression of hepatocellular carcinoma (HCC). Tumor infiltrating immune cells (TILs) was an important component of tumor microenvironment. However, whether TIL features are correla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23eb2dc78e1aff5439bd2bca995e9c32
https://doi.org/10.1016/j.hpb.2020.11.002
https://doi.org/10.1016/j.hpb.2020.11.002
Autor:
Cunzhen Zhang, Guanghui Ding, Zhiwen Ding, Jin Wang, Minggen Hu, Ziliang Qian, Shuang Feng, Yan Meng, Shanshan Li, Haibei Xin, Shupeng Liu, Nan Li
Publikováno v:
Cancer Medicine, Vol 9, Iss 14, Pp 5075-5085 (2020)
Cancer Medicine
Cancer Medicine
Purpose To characterize plasma cell‐free cancer genome chromosomal instabilities (CIN) in patients with liver cancer and to evaluate the potential of CIN as minimally invasive biomarkers for primary liver cancer (PLC) diagnoses. Experimental Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26689be14f41827833f781d98409defa
https://doaj.org/article/8f692d3aa88442c6acf45398c4b5d84f
https://doaj.org/article/8f692d3aa88442c6acf45398c4b5d84f
Autor:
Huiyong Yin, Cunzhen Zhang, Yongqiang Wang, Qiaochu Tu, Min Li, Guijun Liu, Ningning Wang, Shiting Chen, Xuxiao He, Lili Zhang, Nan Li, Xia Shen, Huimin Jiang, Chunzhao Yin, Jingwen Lv, Yongzhen Tao
Publikováno v:
Hepatology (Baltimore, Md.)REFERENCES. 74(6)
Background and aims Insulin receptor (IR) transduces cell surface signal through phosphoinositide 3-kinase (PI3K)-AKT pathways or translocates to the nucleus and binds to the promoters to regulate genes associated with insulin actions, including de n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1a8b9581427b692b75b76e2e944741
https://pubmed.ncbi.nlm.nih.gov/34292642
https://pubmed.ncbi.nlm.nih.gov/34292642