Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Cunren Liu"'
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract Previously, we showed that embryonic deletion of TGF-β type 2 receptor in mouse sclerotome resulted in defects in fibrous connective tissues in the spine. Here we investigated how TGF-β regulates expression of fibrous markers: Scleraxis, F
Externí odkaz:
https://doaj.org/article/e00628fa27cf4f279488dc78fa5d23a1
Publikováno v:
JOR Spine, Vol 1, Iss 2, Pp n/a-n/a (2018)
Background Members of the transforming growth factor beta (TGF‐β) family are secreted proteins that regulate skeletal development. TGF‐β signaling is critical in embryonic development of the annulus fibrosus (AF) of the intervertebral disc (IVD
Externí odkaz:
https://doaj.org/article/e0b04066e5a2491a992c2a38a873daaa
Autor:
Xiaojiang Gao, Nicolas Vince, T. Prescott Atkinson, Maureen P. Martin, Elizabeth E. Brown, Yuge Wang, Carol A. Ballinger, Harry W. Schroeder, Ying Qi, Tracy Hwangpo, Cunren Liu, Ada Elgavish, Peter D. Burrows, Devin Absher, Mary Carrington, Richard J. Reynolds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b1a380c93772fdf09211692d7ea563
https://europepmc.org/articles/PMC5104182/
https://europepmc.org/articles/PMC5104182/
Autor:
Cunren Liu, Shuangyin Zhang, William E. Grizzle, Xiaoyu Xiang, Xiaoying Zhuang, Stephen Barnes, Huang-Ge Zhang, Donald R. Miller, Dongmei Sun, Yuelong Liu
Publikováno v:
Molecular Therapy. 18:1606-1614
Monocyte-derived myeloid cells play vital roles in inflammation-related autoimmune/inflammatory diseases and cancers. Here, we report that exosomes can deliver anti-inflammatory agents, such as curcumin, to activated myeloid cells in vivo. This techn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8d7dfb9cf7b59b001240bc727ec510
https://doi.org/10.1038/mt.2010.105
https://doi.org/10.1038/mt.2010.105
Autor:
Robert W. Hardy, Cunren Liu, Xiaoying Zhuang, Anton Poliakov, Jianhua Wang, Dongmei Sun, Huang-Ge Zhang, Xiaoyu Xiang, Zhongbin Deng, James A. Mobley, Shuangqin Zhang, Spandan V. Shah, Yuelong Liu, Timothy W Garvey, William E. Grizzle, Sue Michalek, Ronald H. Clements
Publikováno v:
Diabetes
OBJECTIVE We sought to determine whether exosome-like vesicles (ELVs) released from adipose tissue play a role in activation of macrophages and subsequent development of insulin resistance in a mouse model. RESEARCH DESIGN AND METHODS ELVs released f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5a8f8d0cc2df99b17d8e9041b66f98
https://doi.org/10.2337/db09-0216
https://doi.org/10.2337/db09-0216
Autor:
Zhongbin Deng, James A. Mobley, Anton Poliakov, Yuelong Liu, Huang-Ge Zhang, Gui-Jun Wang, Jianhua Wang, Xiaoyu Xiang, Liming Zhang, William E. Grizzle, Spandan V. Shah, Cunren Liu, Ziqiang Cheng
Publikováno v:
International Journal of Cancer. 124:2621-2633
Myeloid-derived suppressor cells (MDSCs) promote tumor progression. The mechanisms of MDSC development during tumor growth remain unknown. Tumor exosomes (T-exosomes) have been implicated to play a role in immune regulation, however the role of exoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275bbaa81dc894955a0fc09c42090ff0
https://doi.org/10.1002/ijc.24249
https://doi.org/10.1002/ijc.24249
Autor:
Aijian Qin, Cunren Liu, Gui-Jun Wang, Jianhua Wang, Liming Zhang, William E. Grizzle, Xiaoyu Xiang, Huang-Ge Zhang, Zhongbin Deng, Yuelong Liu, Ziqiang Cheng, Spandan V. Shah
Publikováno v:
The Journal of Immunology. 181:5242-5248
Exosomes released from different types of cells have been proposed to contribute to intercellular communication. We report that thymic exosome-like particles (ELPs) released from cells of the thymus can induce the development of Foxp3+ regulatory T (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43d8c8eacc4a9371021a182d0de8de93
https://doi.org/10.4049/jimmunol.181.8.5242
https://doi.org/10.4049/jimmunol.181.8.5242
Autor:
Cunren Liu, Stephen Barnes, Huang-Ge Zhang, Jianhua Wang, Shaohua Yu, Helen Kim, Robert P. Kimberly, William E. Grizzle
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1773:1116-1123
An important characteristic of tumors is that they at some point in their development overcome the surveillance of the immune system. Tumors secrete exosomes, multivesicular bodies containing a distinct set of proteins that can fuse with cells of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93738ac6a8566d07d238ada179586ac
https://doi.org/10.1016/j.bbamcr.2007.04.015
https://doi.org/10.1016/j.bbamcr.2007.04.015
Autor:
Kaihong Su, Huang-Ge Zhang, Jianhua Wang, William E. Grizzle, Cunren Liu, Yuelong Liu, Liming Zhang, Carla I. Falkson, Robert P. Kimberly, Yingzi Cong, Shaohua Yu, Chuanyu Li
Publikováno v:
The Journal of Immunology. 178:6867-6875
The production of exosomes by tumor cells has been implicated in tumor-associated immune suppression. In this study, we show that, in mice, exosomes produced by TS/A murine mammary tumor cells target CD11b+ myeloid precursors in the bone marrow (BM)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c325fd952d183fe793f117bbb8bd4095
https://doi.org/10.4049/jimmunol.178.11.6867
https://doi.org/10.4049/jimmunol.178.11.6867
Autor:
Huang-Ge Zhang, Jianhua Wang, Cunren Liu, Kaihong Su, Shuangqin Zhang, Liming Zhang, Xu Cao, William E. Grizzle, Robert P. Kimberly, Shaohua Yu
Publikováno v:
The Journal of Immunology. 176:7385-7393
In common with many other cell types, synovial fibroblasts produce exosomes. In this study, we show that the exosomes produced by synovial fibroblasts obtained from individuals with rheumatoid arthritis (RASF), but not exosomes produced by synovial f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02fa4d0769c8022b009acf300889b5d1
https://doi.org/10.4049/jimmunol.176.12.7385
https://doi.org/10.4049/jimmunol.176.12.7385