Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Cunpeng Nie"'
Publikováno v:
ACS Nano. 17:7721-7732
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d20d03ba13b50c448200328d587b048f
https://doi.org/10.1021/acsnano.3c00288
https://doi.org/10.1021/acsnano.3c00288
Publikováno v:
Analytical Chemistry.
Simultaneous imaging and especially visualizing the association of survivin mRNA and telomerase in living cells are of great value for the diagnosis and prognosis of cancer because their co-expression facilitates the development of cancer and identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b2ede277aeb9760abd31656541a390
https://doi.org/10.1021/acs.analchem.2c04531
https://doi.org/10.1021/acs.analchem.2c04531
Publikováno v:
ACS Applied Materials & Interfaces. 13:8015-8025
Deoxyribozyme (DNAzyme) is regarded as a promising gene therapy drug. However, poor cellular uptake efficacy and low biological stability limit the utilization of DNAzyme in gene therapy. Here, we report a well-known programmable DNAzyme-based nanotw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c77aac3cc37383798de99a4ed4f4b85c
https://doi.org/10.1021/acsami.0c21601
https://doi.org/10.1021/acsami.0c21601
Autor:
Xia Chu, Juan Zhang, Yanlei Hu, Cunpeng Nie, Jintao Yi, Manman He, Chang Liu, Ting-Ting Chen, Qingshan Pan, Mengyun He
Publikováno v:
Chemical Communications. 56:3496-3499
In this work, we report a photocontrolled and self-powered DNA walking machine with bipedal DNAzyme walkers for intracellular microRNA imaging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd94bed98e5201d04ced825b9d22471
https://doi.org/10.1039/d0cc00017e
https://doi.org/10.1039/d0cc00017e
Autor:
Xia Chu, Juan Zhang, Qiaoqin Yu, Manman He, Chang Liu, Namin Hu, Ting-Ting Chen, Yafang Wang, Cunpeng Nie, Chuan Zhao
Publikováno v:
Nanoscale. 12:1673-1679
Ribonuclease H (RNase H), an intracellular ribonuclease, plays a crucial role in cellular processes and especially relates to many disease processes. Here, we report a novel signal amplification strategy based on an RNase H-powered DNA walking machin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca277e52e44345bce67f9c99152754c
https://doi.org/10.1039/c9nr07550j
https://doi.org/10.1039/c9nr07550j
Autor:
Namin Hu, Qiaoqin Yu, Manman He, Chuan Zhao, Ting-Ting Chen, Juan Zhang, Yafang Wang, Xia Chu, Cunpeng Nie, Chang Liu
Publikováno v:
Chemical Communications. 56:639-642
In this work, we have developed a novel DNAzyme motor initiated by endogenous enzyme for sensitive imaging of intracellular RNase H activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68e18c74c8bf2e2679f195c89e1a274
https://doi.org/10.1039/c9cc08692g
https://doi.org/10.1039/c9cc08692g
Autor:
Ting-Ting Chen, Ximing Chu, Qingshan Pan, Jintao Yi, Mengyun He, Yanlei Hu, Juan Zhang, Manman He, Xia Chu, Cunpeng Nie
Publikováno v:
ACS applied bio materials. 3(5)
Temozolomide (TMZ), the most common DNA alkylating agent, is predominantly mediated by O6-methylguanine DNA lesions for the treatment of glioblastoma (GBM). When O6-methylguanine-DNA methyltransfer...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1371053f27b2e48d309ffd721aa1fefc
https://pubmed.ncbi.nlm.nih.gov/35025376
https://pubmed.ncbi.nlm.nih.gov/35025376
Autor:
Mengyun He, Qingshan Pan, Xia Chu, Juan Zhang, Cunpeng Nie, Yanlei Hu, Manman He, Chang Liu, Ting-Ting Chen, Jintao Yi
Publikováno v:
ACS Applied Materials & Interfaces. 12:400-409
Drug resistance is a major obstacle to the efficient therapy of drug-resistant cancer. To overcome this problem, we constructed a multifunctional DNA origami-based nanocarrier for codelivery of a chemotherapeutic drug (doxorubicin, Dox) and two diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932915c5424a73252db71f0fb400c774
https://doi.org/10.1021/acsami.9b20707
https://doi.org/10.1021/acsami.9b20707
Autor:
Juan Zhang, Qingshan Pan, Ting-Ting Chen, Manman He, Jintao Yi, Chang Liu, Yanlei Hu, Xia Chu, Cunpeng Nie, Mengyun He
Publikováno v:
Analytical Chemistry. 91:9049-9057
The enzymatic amplification strategy in living cells faces challenges of highly efficient intracellular codelivery of amplification reagents including DNA polymerase. In this work, we develop biomineralized metal-organic framework nanoparticles (MOF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7ecf1654596b378bd3d8e7a0c02e3f
https://doi.org/10.1021/acs.analchem.9b01343
https://doi.org/10.1021/acs.analchem.9b01343
Autor:
Chang Liu, Yu-Jie Zhou, Xia Chu, Cunpeng Nie, Yuan-Hui Wan, Juan Zhang, Ke-Jing Xiao, Ting-Ting Chen
Publikováno v:
Chemical Communications. 55:3278-3281
In this work, we have developed a novel and highly selective signal amplification strategy based on target-assisted self-cleavage DNAzyme probes for multicolor and simultaneous imaging of miRNA-222 and miRNA-223 in living cells. The fluctuation of mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3186073dd47c9333ac9da9f62671780
https://doi.org/10.1039/c9cc00451c
https://doi.org/10.1039/c9cc00451c