Phosphorylation of 'SDT-like' motifs in ATRX mediates its interaction with the MRN complex and is important for ALT pathway suppression.

Autor: Goncalves T; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.; Department of Paediatrics, University of Oxford, Oxford OX3 9DU, UK., Bhatnagar H; Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK., Cunniffe S; Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK., Gibbons RJ; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK., Rose AM; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK.; Department of Paediatrics, University of Oxford, Oxford OX3 9DU, UK., Clynes D; Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK.

Publikováno v: Open biology [Open Biol] 2024 Dec; Vol. 14 (12), pp. 240205. Date of Electronic Publication: 2024 Dec 11.

Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA.

Autor: Rose AM; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK.; Department of Paediatrics, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK., Goncalves T; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK., Cunniffe S; Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK., Geiller HEB; Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK., Kent T; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK., Shepherd S; Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK., Ratnaweera M; Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK., O'Sullivan RJ; Department of Pharmacology and Chemical Biology, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA, USA., Gibbons RJ; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DS, UK., Clynes D; Department of Oncology, University of Oxford, Oxford OX3 7DQ, UK.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2023 Jul 21; Vol. 51 (13), pp. 6509-6527.

Nanocomposite Hydrogels: A Promising Approach for the Treatment of Degenerative Joint Diseases.

Autor: Chen, Qizhu^1,2 (AUTHOR), Zheng, Zitian^3,4 (AUTHOR), Lin, Mian⁵ (AUTHOR), Guo, Zhengyu¹ (AUTHOR), Huang, Hongjie³ (AUTHOR), Xue, Qingyun⁴ (AUTHOR), Jiang, Shengdan² (AUTHOR) jiangshengdan@xinhuamed.com.cn, Wang, Jianquan³ (AUTHOR) wjqsportsmed@163.com, Wu, Aimin¹ (AUTHOR) aiminwu@wmu.edu.cn

Publikováno v: Small Science. Nov2024, Vol. 4 Issue 11, p1-34. 34p.

Integrated bioinformatics analysis and experimental validation to understand tryptophan metabolism-related genes in hepatocellular carcinoma.

Autor: Hao Chen^1,2,3, Wu Sun⁴, Mengxiao Xie⁵, Zhenhan Li⁶, Bofeng Chen⁷, Tao Zhang⁷, Le Lv⁸, Lizhen Wang³, Linming Lu³, Qianli Tang¹ htmgx@ymun.edu.cn, Liangping Luo⁹

Publikováno v: Journal of Cancer. 2024, Vol. 15 Issue 15, p4879-4892. 14p.

Interplay between base excision repair protein XRCC1 and ALDH2 predicts overall survival in lung and liver cancer patients.

Autor: Chen X; CRUK & MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK.; Research Centre of Clinical Medicine, Affiliated Hospital of Nantong University, Jiangsu, China.; School of Life Science, Nantong University, Nantong, China., Legrand AJ; CRUK & MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., Cunniffe S; CRUK & MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., Hume S; CRUK & MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., Poletto M; CRUK & MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., Vaz B; CRUK & MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., Ramadan K; CRUK & MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK., Yao D; Research Centre of Clinical Medicine, Affiliated Hospital of Nantong University, Jiangsu, China. yaodf@ahmnc.com., Dianov GL; CRUK & MRC Oxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, UK. grigory.dianov@oncology.ox.ac.uk.; Institute of Cytology and Genetics, Russian Academy of Sciences, Lavrentyeva 10, Novosibirsk, Russian Federation, 630090. grigory.dianov@oncology.ox.ac.uk.; Novosibirsk State University, Novosibirsk, Russian Federation, 63000. grigory.dianov@oncology.ox.ac.uk.

Publikováno v: Cellular oncology (Dordrecht) [Cell Oncol (Dordr)] 2018 Oct; Vol. 41 (5), pp. 527-539. Date of Electronic Publication: 2018 Aug 07.