Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Cunnea, P."'
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Toll-like receptors (TLRs) are pattern recognition receptors, originally discovered to stimulate innate immune reactions against microbial infection. TLRs also play essential roles in bridging the innate and adaptive immune system, playing multiple r
Externí odkaz:
https://doaj.org/article/4aa5fd08ee004d61bf94a8ac326c8744
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Epithelial ovarian cancer (EOC) is a heterogenous disease associated with variations in presentation, pathology and prognosis. Advanced EOC is typified by frequent relapse and a historical 5-year survival of less than 30% despite improvements in surg
Externí odkaz:
https://doaj.org/article/e67b8031f7254b7699dc4757aa3601d2
Autor:
Haonan Lu, Mubarik Arshad, Andrew Thornton, Giacomo Avesani, Paula Cunnea, Ed Curry, Fahdi Kanavati, Jack Liang, Katherine Nixon, Sophie T. Williams, Mona Ali Hassan, David D. L. Bowtell, Hani Gabra, Christina Fotopoulou, Andrea Rockall, Eric O. Aboagye
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Radiomics—the quantification of features within tumor images—has shown prognostic potential in cancer. Here, the authors use a machine learning approach to develop a radiomic-based small set of descriptors to predict ovarian cancer patient surviv
Externí odkaz:
https://doaj.org/article/7fff94167bb54d9d9ccc2351fa73055a
Autor:
Sarah C Johnson, Sanjukta Chakraborty, Anastasios Drosou, Paula Cunnea, Dimitrios Tzovaras, Katherine Nixon, David C Zawieja, Mariappan Muthuchamy, Christina Fotopoulou, James E Moore
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0230092 (2020)
Lymphogenic spread is associated with poor prognosis in epithelial ovarian cancer (EOC), yet little is known regarding roles of non-peri-tumoural lymphatic vessels (LVs) outside the tumour microenvironment that may impact relapse. The aim of this fea
Externí odkaz:
https://doaj.org/article/35eded80e8dc4494b0e09d3273e722f3
Autor:
Paula Cunnea, Tommy Gorgy, Konstantinos Petkos, Sally A.N. Gowers, Haonan Lu, Cristina Morera, Wen Wu, Phillip Lawton, Katherine Nixon, Chi Leng Leong, Flavia Sorbi, Lavinia Domenici, Andrew Paterson, Ed Curry, Hani Gabra, Martyn G. Boutelle, Emmanuel M. Drakakis, Christina Fotopoulou
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Currently, there are no valid pre-operatively established biomarkers or algorithms that can accurately predict surgical and clinical outcome for patients with advanced epithelial ovarian cancer (EOC). In this study, we suggest that profiling
Externí odkaz:
https://doaj.org/article/cc3db571882b4b56b949edfb1aa0edd7
Autor:
M. Yusuf, F. Zhang, B. Chen, A. Bhartiya, K. Cunnea, U. Wagner, F. Cacho-Nerin, J. Schwenke, I. K. Robinson
Publikováno v:
IUCrJ, Vol 4, Iss 2, Pp 147-151 (2017)
Biological sample-preparation procedures have been developed for imaging human chromosomes under cryogenic conditions. A new experimental setup, developed for imaging frozen samples using beamline I13 at Diamond Light Source, is described. This manus
Externí odkaz:
https://doaj.org/article/d1a02a207e8a4f3b9f46f671d040a333
Akademický článek
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Autor:
Cunnea, P, Curry, E, Christie, E, Nixon, K, Kwok, CH, Pandey, A, Wulandari, R, Thol, K, Ploski, J, Morera-Albert, C, McQuaid, S, Lozano-Kuehne, J, Clark, JJ, Krell, J, Stronach, E, McNeish, I, Bowtell, D, Fotopoulou, C
Limited evidence exists on the impact of spatial and temporal heterogeneity of high-grade serous ovarian cancer (HGSOC) on tumour evolution, clinical outcomes and surgical operability. We perform systematic multi-site tumour mapping at presentation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::94eaadf1f3c04780074303ecacc7cff8
http://hdl.handle.net/10044/1/104322
http://hdl.handle.net/10044/1/104322
Autor:
Dimitrios Athanasiou, Lowell T Edgar, Mohammad Jafarnejad, Katherine Nixon, Delfim Duarte, Edwin D Hawkins, Samira Jamalian, Paula Cunnea, Cristina Lo Celso, Shunichi Kobayashi, Christina Fotopoulou, James E Moore
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183222 (2017)
The lymphatic system has a major significance in the metastatic pathways in women's cancers. Lymphatic pumping depends on both extrinsic and intrinsic mechanisms, and the mechanical behavior of lymphatic vessels regulates the function of the system.
Externí odkaz:
https://doaj.org/article/46d9130ec6e24b91829bcbb89d6f0246
Akademický článek
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