Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Cun-Gen Ma"'
Autor:
Yan-Rong Li, Ruo-Nan Zhang, Rui-Rui Sun, Yan-Yan Li, Bo Zhang, Xiao-Ming Jin, Hai-Fei Zhang, Bao-Guo Xiao, Cun-Gen Ma, Hui-Jie Fan, Zhi Chai
Publikováno v:
Heliyon, Vol 9, Iss 10, Pp e20621- (2023)
Objective: Studies have shown that Wuzi Yanzong Pill (WYP) can be used to treat neurological diseases, but its mechanisms for multiple sclerosis (MS) remain unclear. This study aims to determine the effect of WYP on MS in an animal model of experimen
Externí odkaz:
https://doaj.org/article/eee5080cbd5146b99308035ff788384c
Autor:
Yi-Ge Wu, Li-Juan Song, Li-Jun Yin, Jun-Jun Yin, Qing Wang, Jie-Zhong Yu, Bao-Guo Xiao, Cun-Gen Ma
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 947-954 (2023)
Microglia are resident immune cells in the central nervous system. During the pathogenesis of Alzheimer’s disease, stimulatory factors continuously act on the microglia causing abnormal activation and unbalanced phenotypic changes; these events hav
Externí odkaz:
https://doaj.org/article/18c64338d9554fcb894d54c0f2a682c4
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106233- (2023)
Stroke is the most common cause of acquired epilepsy, but treatment for preventing the development of post-stroke epilepsy is still unavailable. Since stroke results in neuronal damage and death as well as initial loss of activity in the affected bra
Externí odkaz:
https://doaj.org/article/f7f4c615d1af4b65bee7cf17c7e01d56
Autor:
Hailong Yan, Yuqing Yan, Ye Gao, Nianping Zhang, Gajendra Kumar, Qingli Fang, Ziqing Li, Jiehui Li, Yuna Zhang, Lijuan Song, Jiawei Wang, Jingxian Sun, Han-Ting Zhang, Cun-Gen Ma
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Alzheimer's disease (AD) is the most common cause of progressive dementia. In the present study, we showed hippocampal tissue transcriptome analysis in APPswe/PSEN1dE9 (APP/PS1, AD model) mice treated with fasudil (ADF) and compared with AD
Externí odkaz:
https://doaj.org/article/36e2c6ca599a40629288f2274adb0c72
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 12, Pp 2623-2631 (2022)
Ras homolog (Rho)-associated kinases (ROCKs) belong to the serine-threonine kinase family, which plays a pivotal role in regulating the damage, survival, axon guidance, and regeneration of neurons. ROCKs are also involved in the biological effects of
Externí odkaz:
https://doaj.org/article/8fde7ae105ca49a4b5499c0613b60fd5
Autor:
Yuan Zhang, Xin-Yu Lu, Ze-Qin Ye, Bogoljub Ciric, Cun-Gen Ma, Abdolmohamad Rostami, Xing Li, Guang-Xian Zhang
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/f51d2ee1aace4b1fa6263368dd69d803
Autor:
Yan-Rong Li, Meng-Ying Sun, Wei Hang, Qi Xiao, Hui-Jie Fan, Lu Jia, Xiao-Ming Jin, Bo Zhang, Bao-Guo Xiao, Cun-Gen Ma, Zhi Chai
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12277- (2022)
Ethnopharmacology relevance: Wuzi Yanzong Pill (WYP), a well-known prescription for invigorating the kidney and essence, which is widely used to treat infertility such as oligoasthenospermia. Studies have shown that WYP can be used to treat neurologi
Externí odkaz:
https://doaj.org/article/959f4597c72d44458cc947bc9fc8f28f
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 9, Pp 1702-1710 (2021)
Astrocytes play multifaceted and vital roles in maintaining neurophysiological function of the central nervous system by regulating homeostasis, increasing synaptic plasticity, and sustaining neuroprotective effects. Astrocytes become activated as a
Externí odkaz:
https://doaj.org/article/76c272200a444dbea983f699d6e66db1
Autor:
Min-Fang Guo, Hui-Yu Zhang, Pei-Jun Zhang, Xiao-Qin Liu, Li-Juan Song, Wen-Yue Wei, Yu-Yin Wang, Bing-Tao Mu, Zhi Chai, Jie-Zhong Yu, Cun-Gen Ma
Publikováno v:
Journal of Integrative Neuroscience, Vol 19, Iss 4, Pp 651-662 (2020)
Recent studies have shown that Nogo-A and the Nogo-A receptor affect β-amyloid metabolism and the downstream Rho GTP enzyme signaling pathway, which may affect the levels of β-amyloid and tau. Nogo-A may play a key role in the pathogenesis of Alzhe
Externí odkaz:
https://doaj.org/article/79a592c5223f4068bd88517cadaa395b
Autor:
Yuqing Yan, Ye Gao, Qingli Fang, Nianping Zhang, Gajendra Kumar, Hailong Yan, Lijuan Song, Jiehui Li, Yuna Zhang, Jingxian Sun, Jiawei Wang, Linhu Zhao, Keith Skaggs, Han-Ting Zhang, Cun-Gen Ma
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background: Fasudil, a Rho kinase inhibitor, exerts therapeutic effects in a mouse model of Alzheimer's disease (AD), a chronic neurodegenerative disease with progressive loss of memory. However, the mechanisms remain unclear. In addition, the gut mi
Externí odkaz:
https://doaj.org/article/71981e75a54f4006b0175d0ffbce1cef