Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Cun-Dong Fan"'
Autor:
Lei Zhang, Yan Li, Cun-dong Fan, Yong-Hao Jiang, Li-song Sheng, Xu-yu Song, Yu-xing Lin, Yi-Tao Xue, Rong Sun
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116548- (2024)
Background: Various heart diseases ultimately lead to chronic heart failure (CHF). In CHF, the inflammatory response is associated with pyroptosis, which is mediated by the NOD-like receptor protein 3 (NLRP3) inflammasome. Fu Xin decoction (FXD) is c
Externí odkaz:
https://doaj.org/article/4616ac17045d406d9aa56c0974567353
Autor:
Jing-yi Sun, Ya-jun Hou, Yi-bo Yin, Feng-ze Wang, Ming-feng Yang, Yuan-ying Zhang, Cun-dong Fan, Bao-liang Sun
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 132, Iss , Pp 110931- (2020)
Externí odkaz:
https://doaj.org/article/9fbb850509d14bb88505b5bb7891e384
Autor:
Jing-yi Sun, Ya-jun Hou, Yi-bo Yin, Feng-ze Wang, Ming-feng Yang, Yuan-ying Zhang, Cun-dong Fan, Bao-liang Sun
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 130, Iss , Pp 110544- (2020)
Osteosarcoma is a highly invasive primary malignant bone tumor. PI3K/mTOR pathway plays a key role in tumor progression, and inhibition of PI3K/mTOR pathway represents a novel strategy in therapy of osteosarcoma. CCT128930 and VS5584 are both inhibit
Externí odkaz:
https://doaj.org/article/567acf6008284085bf6db1446e1d7ca5
Autor:
Cun-dong Fan, Xiao-yan Fu, Zong-yong Zhang, Ming-zhi Cao, Jing-yi Sun, Ming-feng Yang, Xiao-ting Fu, Shi-jun Zhao, Lu-rong Shao, Hui-fang Zhang, Xiao-yi Yang, Bao-liang Sun
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Thioredoxin reductase (TrxR) as a selenium (Se)-containing antioxidase plays key role in regulating intracellular redox status. Selenocystine (SeC) a natural available Se-containing amino acid showed novel anticancer potential through trigge
Externí odkaz:
https://doaj.org/article/aa5007e439df488c8463e0c4fd458bc4
Autor:
Jing-yi Sun, Ya-jun Hou, Xiao-yan Fu, Xiao-ting Fu, Jin-kui Ma, Ming-feng Yang, Bao-liang Sun, Cun-dong Fan, Jinrok Oh
Publikováno v:
Frontiers in Physiology, Vol 9 (2019)
Accumulated evidences have verified that cancer chemotherapy may increase the risk of osteoporosis and severely affected the life quality. Osteoclasts hyperactivation was commonly accepted as the major pathogenesis of osteoporosis. However, the role
Externí odkaz:
https://doaj.org/article/bffebdc0b45a4558ada017be42fea6f4
Autor:
Cun-dong Fan, Jing-yi Sun, Xiao-ting Fu, Ya-jun Hou, Yuan Li, Ming-feng Yang, Xiao-yan Fu, Bao-liang Sun
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Homocysteine (Hcy) as an independent risk factor contributes to the occurrence and development of human cardiovascular diseases (CVD). Induction of oxidative stress and apoptosis was commonly accepted as the major mechanism in Hcy-induced cardiotoxic
Externí odkaz:
https://doaj.org/article/a75a2004fb8f46abad7834ea134161e7
Autor:
Fan-Shuo Zeng, Chao Yu, Xiao-Yan Fu, Bao-Liang Sun, Qiang-San Sun, Qin Wang, Cun-Dong Fan, Xiao-Jing Yuan, Ping Li
Publikováno v:
Neurochemical Research. 46:1112-1118
Immune response plays a vital role in the pathogenesis of neuropathic pain. Immune response-targeted therapy becomes an effective strategy for treating neuropathic pain. Licochalcone A (Lic-A) possesses anti-inflammatory and neuroprotective effects.
Autor:
Cheng Zhang, Cun-dong Fan, Ming-feng Yang, Jin Rok Oh, Feng-ze Wang, Ya-jun Hou, Zheng Sun, Baoliang Sun, Hai-Juan Cui, Jing-yi Sun
Publikováno v:
Current Cancer Drug Targets. 20:616-623
Background: Activation of PI3K/mTOR signaling pathway plays key role in the progression of human osteosarcoma. Studies have confirmed that VS-5584 was a novel inhibitor of PI3K/mTOR pathway, and displayed potential anticancer activity. Objective: To
Autor:
Yuan-ying Zhang, Cun-dong Fan, Ming-feng Yang, Feng-ze Wang, Jing-yi Sun, Baoliang Sun, Yi-bo Yin, Ya-jun Hou
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 132, Iss, Pp 110931-(2020)
Autor:
Feng-ze Wang, Jing-yi Sun, Cun-dong Fan, Ming-feng Yang, Baoliang Sun, Yuan-ying Zhang, Yi-bo Yin, Ya-jun Hou
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 130, Iss, Pp 110544-(2020)
Osteosarcoma is a highly invasive primary malignant bone tumor. PI3K/mTOR pathway plays a key role in tumor progression, and inhibition of PI3K/mTOR pathway represents a novel strategy in therapy of osteosarcoma. CCT128930 and VS5584 are both inhibit