Large genetic analysis of alcohol resistance and tolerance reveals an inverse correlation and suggests 'true' tolerance mutants.

Autor: Chvilicek MM; Department of Psychiatry, Huntsman Mental Health Institute, School of Medicine, University of Utah, Salt Lake City, USA.; Neuroscience Graduate Program, University of Utah, Salt Lake City, USA., Seguin A; Molecular Medicine Program, School of Medicine, University of Utah, Salt Lake City, USA., Lathen DR; Department of Psychiatry, Huntsman Mental Health Institute, School of Medicine, University of Utah, Salt Lake City, USA.; Neuroscience Graduate Program, University of Utah, Salt Lake City, USA., Titos I; Department of Psychiatry, Huntsman Mental Health Institute, School of Medicine, University of Utah, Salt Lake City, USA., Cummins-Beebe PN; Department of Psychiatry, Huntsman Mental Health Institute, School of Medicine, University of Utah, Salt Lake City, USA.; Neuroscience Graduate Program, University of Utah, Salt Lake City, USA., Pabon MA; Molecular Medicine Program, School of Medicine, University of Utah, Salt Lake City, USA., Miscevic M; Molecular Medicine Program, School of Medicine, University of Utah, Salt Lake City, USA., Nickel EA; Molecular Medicine Program, School of Medicine, University of Utah, Salt Lake City, USA., Merrill CB; Department of Psychiatry, Huntsman Mental Health Institute, School of Medicine, University of Utah, Salt Lake City, USA., Rodan AR; Molecular Medicine Program, School of Medicine, University of Utah, Salt Lake City, USA.; Division of Nephrology, Department of Internal Medicine, School of Medicine, University of Utah, Salt Lake City, USA.; Medical Service, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, USA.; Department of Human Genetics, School of Medicine, University of Utah, Salt Lake City, USA., Rothenfluh A; Department of Psychiatry, Huntsman Mental Health Institute, School of Medicine, University of Utah, Salt Lake City, USA.; Neuroscience Graduate Program, University of Utah, Salt Lake City, USA.; Molecular Medicine Program, School of Medicine, University of Utah, Salt Lake City, USA.; Department of Human Genetics, School of Medicine, University of Utah, Salt Lake City, USA.; Department of Neurobiology, School of Medicine, University of Utah, Salt Lake City, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 10. Date of Electronic Publication: 2023 Oct 10.