Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Cumhur G. Ekmekçi"'
Autor:
Cumhur G. Ekmekçi, Neslihan Abaci, Sema Sirma Ekmekci, Burcu Salman, Melda Sariman, Zeliha Emrence, Çağrı Güleç
Publikováno v:
Turkish Journal of Hematology, Vol 37, Iss 4, Pp 226-233 (2020)
Turkish Journal of Hematology
Turkish Journal of Hematology
Objective T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease resulting from the accumulation of genetic changes that affect the development of T-cells. The precise role of lymphoid enhancer-binding factor 1 (LEF1) in T-ALL has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2971123e1074cc64e977ecac14f5bc0
https://tjh.com.tr/jvi.aspx?pdir=tjh&plng=eng&un=TJH-33239&look4=
https://tjh.com.tr/jvi.aspx?pdir=tjh&plng=eng&un=TJH-33239&look4=
Publikováno v:
Bezmiâlem Science, Vol 7, Iss 2, Pp 86-94 (2019)
Bezmialem Science
Bezmialem Science
Objective: genomic DNA obtained from paraffin blocks of the intended colorectal cancer cases was evaluated for promoting colorectal cancer by investigating the promoter methylation of 6 different gene promoter regions and microsatellite instability.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553f01c76e25872accfb815e5628a991
https://doaj.org/article/f5da8253acd942769afc466c77509fbb
https://doaj.org/article/f5da8253acd942769afc466c77509fbb
Autor:
Ugur Ozbek, Cumhur G. Ekmekçi
Publikováno v:
Experimed. 8:62-70
DOI : 10.26650/experimed.2018. 473615 Objectives : The hypermethylator phenotype is used as a term for both acute myeloid leukemia (AML) and other tumors. We analyzed the methylation statuses of ten genes (DAP-kinase, SOCS1, ER, p15, Ecadherin, RAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d506cecb4823ab85be8688c49afbb4f
https://doi.org/10.26650/experimed.2019.473615
https://doi.org/10.26650/experimed.2019.473615
Autor:
Cumhur G. Ekmekçi, Ugur Ozbek
Publikováno v:
Volume: 8, Issue: 3 79-83
Experimed
Experimed
DOI:10.26650/experimed.2018.18005Objective: The enzyme thymidylate synthase(TS) in the folate metabolism catalyzes the conversion of deoxyuridinemonophosphate (dUMP) to deoxythymidine monophosphate (dTMP). It provides acertain balance of deoxynucleot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a09ce5d2d0597110daa7d07f9ec4de3
https://dergipark.org.tr/tr/pub/experimed/issue/43462/530314
https://dergipark.org.tr/tr/pub/experimed/issue/43462/530314
Autor:
Cumhur G. Ekmekçi, Ahmet Gül, Sadakat Ozdil, Duran Ustek, Filiz Akyuz, Kadir Demir, Binnur Pinarbasi, Fatih Besisik, Aytul Uyar, Zeynel Mungan, Güngör Boztaş, Sabahattin Kaymakoglu
Publikováno v:
Journal of Clinical Gastroenterology. 47:e23-e27
Association of NOD2 (CARD15) gene mutations with inflammatory bowel diseases (IBD) is well known. We herein aimed to investigate the role of familial Mediterranean fever-associated MEFV variations in IBD patients as additional regional-specific risk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4191bffa261e66e4b351a3b93de5bc6b
https://doi.org/10.1097/mcg.0b013e3182597992
https://doi.org/10.1097/mcg.0b013e3182597992
Publikováno v:
American Journal of Hematology. 77:233-240
Hypermethylator phenotype, a propensity of tumors to incur nonrandom concurrent methylation, has been described in several tumors, including acute myeloid leukemia (AML). More recent studies identified methylation of other tumor suppressor genes, DAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37fe9fc0c4fc41edaa464cdcce497355
https://doi.org/10.1002/ajh.20186
https://doi.org/10.1002/ajh.20186
Autor:
Ugur Ozbek, Hakan Yanar, Basar Oku, Aris Cakiris, Burçak Vural, Duran Ustek, Ahmet Gül, Fatih Selcukbiricik, Cumhur G. Ekmekçi, Korhan Taviloğlu
Publikováno v:
Arthritis and rheumatism. 56(1)
Objective Familial Mediterranean fever (FMF) is associated with more than 70 missense mutations in the MEFV gene. The purpose of this study was to investigate the relative expression of messenger RNA (mRNA) for the MEFV gene in peripheral blood leuko
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37277138d723cbb8ff1c7d422e6a791
https://pubmed.ncbi.nlm.nih.gov/17195238
https://pubmed.ncbi.nlm.nih.gov/17195238
Publikováno v:
Blood. 104:4308-4308
SET gene, also known as TAF-I beta, was originally identified as a component of the SET-CAN fusion gene, which results from t(9;9) translocation, in a patient with acute undifferentiated leukemia (AUL). SET gene encodes a nuclear phosphoprotein that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b706b57abb7deaca49e7b8e9935402b8
https://doi.org/10.1182/blood.v104.11.4308.4308
https://doi.org/10.1182/blood.v104.11.4308.4308
Autor:
Khalid Siraj, Kishor Bhatia, Cumhur G. Ekmekçi, Sema Sirma, Ugur Ozbek, Duran Ustek, Marina Gutierrez
Publikováno v:
Blood. 104:4474-4474
Global DNA hypomethylation is followed by regional hypermethylation occur in tumorigenesis and these hypermethylation is often associated with the inactivation of the tumor supresser genes. DNA methyltransferases are known to be responsible for the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2f53e0970116d8e614478b681cce5f5
https://doi.org/10.1182/blood.v104.11.4474.4474
https://doi.org/10.1182/blood.v104.11.4474.4474