Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Culton R Hensley"'
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Liver hepatocellular carcinoma (LIHC) is the major form of liver cancer that is the fourth most common cause of cancer death worldwide. It has been reported that the multifunctional protein p62 (also known as SQSTM1) plays a cancer-promoting role in
Externí odkaz:
https://doaj.org/article/733b6fad8b03446c8dec326c0a68804d
Autor:
Ling Wang, Mary E. A. Howell, Ayrianna Sparks-Wallace, Juan Zhao, Culton R. Hensley, Camri A. Nicksic, Shanna R. Horne, Kaylea B. Mohr, Jonathan P. Moorman, Zhi Q. Yao, Shunbin Ning
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
As a ubiquitin sensor and a signal-transducing adaptor, p62 is crucial for NF-κB activation, which involves the ubiquitin machinery in diverse contexts. However, whether p62 is required for EBV LMP1 activation of NF-κB is an open question.
Externí odkaz:
https://doaj.org/article/9062215602b446458b173e626e8fb19d
Autor:
Culton R Hensley, Camri A Nicksic, Shunbin Ning, Mary E A Howell, Jonathan P. Moorman, Kaylea B Mohr, Juan Zhao, Zhi Q. Yao, Ling Wang, Shanna R Horne, Ayrianna Sparks-Wallace
Publikováno v:
mBio
mBio, Vol 12, Iss 5 (2021)
mBio, Vol 12, Iss 5 (2021)
The Epstein-Barr virus (EBV) protein LMP1 serves as a paradigm that engages complicated ubiquitination-mediated mechanisms to activate multiple transcription factors. p62 is a ubiquitin sensor and a signal-transducing adaptor that has multiple functi