Phase Ib study of eltrombopag and azacitidine in patients with high‐risk myelodysplastic syndromes and related disorders (the ELASTIC study)

Autor: Sternberg, A, Boucher, R, Coulthard, HC, Raghavan, M, Culligan, D, Jackson, A, Cargo, C, Dennis, M, Metzner, M, O'Sullivan, J, Moore, R, Bowen, D, Vyas, P

Publikováno v: British Journal of Haematology. 199:222-229

Treating adverse risk myelodysplastic syndromes with azacitidine exacerbates thrombocytopenia. We report a study of eltrombopag in combination with azacitidine using a 3 + 3 cohort design. Patients with baseline platelets of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::485aefa1e6656911555001baca16f36b
https://doi.org/10.1111/bjh.18389

Toxic iron species in lower-risk myelodysplastic syndrome patients : course of disease and effects on outcome

Autor: Hoeks, Marlijn, Bagguley, Tim, van Marrewijk, Corine, Smith, Alex, Bowen, David, Culligan, Dominic, Kolade, Seye, Symeonidis, Argiris, Garelius, Hege, Spanoudakis, Michail, Langemeijer, Saskia, Roelofs, Rian, Wiegerinck, Erwin, Tatic, Aurelia, Killick, Sally, Panagiotidis, Panagiotis, Stanca, Oana, Hellström-Lindberg, Eva, Cermak, Jaroslav, van der Klauw, Melanie, Wouters, Hanneke, van Kraaij, Marian, Blijlevens, Nicole, Swinkels, Dorine W., de Witte, Theo, Stauder, R., Walder, A., Pfeilstöcker, M., Schoenmetzler-Makrai, A., Burgstaller, S., Thaler, J., Mandac Rogulj, I., Krejci, M., Voglova, J., Rohon, P., Jonasova, A., Cermak, J., Mikulenkova, D., Hochova, I., Jensen, P. D., Holm, M. S., Kjeldsen, L., Dufva, I. H., Vestergaard, H., Re, D., Slama, B., Fenaux, P., Choufi, B., Cheze, S., Klepping, D., Salles, B., de Renzis, B., Willems, L., De Prost, D., Gutnecht, J., Courby, S., Siguret, V., Tertian, G., Pascal, L., Chaury, M., Wattel, E., Guerci, A., Legros, L., Itzykson, R., Ades, L., Isnard, F., Sanhes, L., Benramdane, R., Stamatoullas, A., Amé, S., Beyne-Rauzy, O., Gyan, E., Platzbecker, U., Badrakan, C., Germing, U., Lübbert, M., Schlenk, R., Kotsianidis, I., Tsatalas, C., Pappa, V., Galanopoulos, A., Michali, E., Panagiotidis, P., Viniou, N., Katsigiannis, A., Roussou, P., Terpos, E., Kostourou, A., Kartasis, Z., Pouli, A., Palla, K., Briasoulis, V., Hatzimichael, E., Vassilopoulos, G., Symeonidis, A., Kourakli, A., Zikos, P., Anagnostopoulos, A., Kotsopoulou, M., Megalakaki, K., Protopapa, M., Vlachaki, E., Konstantinidou, P., Stemer, G., Nemetz, A., Gotwin, U., Cohen, O., Koren, M., Levy, E., Greenbaum, U., Gino-Moor, S., Price, M., Ofran, Y., Winder, A., Goldshmidt, N., Elias, S., Sabag, R., Hellman, I., Ellis, M., Braester, A., Rosenbaum, H., Berdichevsky, S., Itzhaki, G., Wolaj, O., Yeganeh, S., Katz, O., Filanovsky, K., Dali, N., Mittelman, M., Malcovati, L., Fianchi, L., vd Loosdrecht, A., Matthijssen, V., Herbers, A., Pruijt, H., Aboosy, N., de Vries, F., Velders, G., Jacobs, E., Langemeijer, S., MacKenzie, M., Lensen, C., Kuijper, P., Madry, K., Camara, M., Almeida, A., Vulkan, G., Stanca Ciocan, O., Tatic, A., Savic, A., Pedro, C., Xicoy, B., Leiva, P., Munoz, J., Betes, V., Benavente, C., Lozano, M., Martinez, M., Iniesta, P., Bernal, T., Diez Campelo, M., Tormo, D., Andreu Lapiedra, R., Sanz, G., Hesse Sundin, E., Garelius, H., Karlsson, C., Antunovic, P., Jönsson, A., Brandefors, L., Nilsson, L., Kozlowski, P., Hellstrom-Lindberg, E., Grövdal, M., Larsson, K., Wallvik, J., Lorenz, F., Ejerblad, E., Culligan, D., Craddock, C., Kolade, S., Cahalin, P., Killick, S., Ackroyd, S., Wong, C., Warren, A., Drummond, M., Hall, C., Rothwell, K., Green, S., Ali, S., Bowen, D., Karakantza, M., Dennis, M., Jones, G., Parker, J., Bowen, A., Radia, R., Das-Gupta, E., Vyas, P., Nga, E., Creagh, D., Ashcroft, J., Mills, J., Bond, L.

Publikováno v: Hoeks, M, Bagguley, T, van Marrewijk, C, Smith, A, Bowen, D, Culligan, D, Kolade, S, Symeonidis, A, Garelius, H, Spanoudakis, M, Langemeijer, S, Roelofs, R, Wiegerinck, E, Tatic, A, Killick, S, Panagiotidis, P, Stanca, O, Hellström-Lindberg, E, Cermak, J, van der Klauw, M, Wouters, H, van Kraaij, M, Blijlevens, N, Swinkels, D W, de Witte, T, Stauder, R, Walder, A, Pfeilstöcker, M, Schoenmetzler-Makrai, A, Burgstaller, S, Thaler, J, Mandac Rogulj, I, Krejci, M, Voglova, J, Rohon, P, Jonasova, A, Cermak, J, Mikulenkova, D, Hochova, I, Jensen, P D, Holm, M S, Kjeldsen, L, Dufva, I H, Vestergaard, H, Re, D, Slama, B, Fenaux, P, Choufi, B, Cheze, S, Klepping, D, Salles, B, de Renzis, B, Willems, L, De Prost, D, Gutnecht, J, Courby, S, Siguret, V, Tertian, G, Pascal, L, Chaury, M, Wattel, E, Guerci, A, Legros, L, Itzykson, R, Ades, L, Isnard, F, Sanhes, L, Benramdane, R, Stamatoullas, A, Amé, S, Beyne-Rauzy, O, Gyan, E, Platzbecker, U, Badrakan, C, Germing, U, Lübbert, M, Schlenk, R, Kotsianidis, I, Tsatalas, C, Pappa, V, Galanopoulos, A, Michali, E, Panagiotidis, P, Viniou, N, Katsigiannis, A, Roussou, P, Terpos, E, Kostourou, A, Kartasis, Z, Pouli, A, Palla, K, Briasoulis, V, Hatzimichael, E, Vassilopoulos, G, Symeonidis, A, Kourakli, A, Zikos, P, Anagnostopoulos, A, Kotsopoulou, M, Megalakaki, K, Protopapa, M, Vlachaki, E, Konstantinidou, P, Stemer, G, Nemetz, A, Gotwin, U, Cohen, O, Koren, M, Levy, E, Greenbaum, U, Gino-Moor, S, Price, M, Ofran, Y, Winder, A, Goldshmidt, N, Elias, S, Sabag, R, Hellman, I, Ellis, M, Braester, A, Rosenbaum, H, Berdichevsky, S, Itzhaki, G, Wolaj, O, Yeganeh, S, Katz, O, Filanovsky, K, Dali, N, Mittelman, M, Malcovati, L, Fianchi, L, vd Loosdrecht, A, Matthijssen, V, Herbers, A, Pruijt, H, Aboosy, N, de Vries, F, Velders, G, Jacobs, E, Langemeijer, S, MacKenzie, M, Lensen, C, Kuijper, P, Madry, K, Camara, M, Almeida, A, Vulkan, G, Stanca Ciocan, O, Tatic, A, Savic, A, Pedro, C, Xicoy, B, Leiva, P, Munoz, J, Betes, V, Benavente, C, Lozano, M, Martinez, M, Iniesta, P, Bernal, T, Diez Campelo, M, Tormo, D, Andreu Lapiedra, R, Sanz, G, Hesse Sundin, E, Garelius, H, Karlsson, C, Antunovic, P, Jönsson, A, Brandefors, L, Nilsson, L, Kozlowski, P, Hellstrom-Lindberg, E, Grövdal, M, Larsson, K, Wallvik, J, Lorenz, F, Ejerblad, E, Culligan, D, Craddock, C, Kolade, S, Cahalin, P, Killick, S, Ackroyd, S, Wong, C, Warren, A, Drummond, M, Hall, C, Rothwell, K, Green, S, Ali, S, Karakantza, M, Dennis, M, Jones, G, Parker, J, Bowen, A, Radia, R, Das-Gupta, E, Vyas, P, Nga, E, Creagh, D, Ashcroft, J, Mills, J, Bond, L & the EUMDS Registry Participants 2021, ' Toxic iron species in lower-risk myelodysplastic syndrome patients : course of disease and effects on outcome ', Leukemia, vol. 35, no. 6, pp. 1745-1750 . https://doi.org/10.1038/s41375-020-01022-2
on behalf of the EUMDS Registry Participants 2021, ' Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome ', Leukemia, vol. 35, no. 6, pp. 1745-1750 . https://doi.org/10.1038/s41375-020-01022-2
Hoeks, M, Bagguley, T, van Marrewijk, C, Smith, A, Bowen, D, Culligan, D, Kolade, S, Symeonidis, A, Garelius, H, Spanoudakis, M, Langemeijer, S, Roelofs, R, Wiegerinck, E, Tatic, A, Killick, S, Panagiotidis, P, Stanca, O, Hellström-Lindberg, E, Cermak, J, van der Klauw, M, Wouters, H, van Kraaij, M, Blijlevens, N, Swinkels, D W, de Witte, T, on behalf of the EUMDS Registry Participants & Vestergaard, H 2021, ' Toxic iron species in lower-risk myelodysplastic syndrome patients : course of disease and effects on outcome ', Leukemia, vol. 35, no. 6, pp. 1745-1750 . https://doi.org/10.1038/s41375-020-01022-2
Leukemia, 35, 1745-1750
Leukemia, 35, 1745-1750. Nature Publishing Group
Leukemia, 35(6), 1745-1750. Nature Publishing Group
Leukemia, 35, 6, pp. 1745-1750
Leukemia

Red blood cell transfusions (RBCT) remain the cornerstone of supportive care in lower-risk myelodysplastic syndrome (LRMDS) [1]. Transfusion dependency in LRMDS patients is associated with inferior outcomes, mainly attributed to severe bone marrow fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23cc5efb8d641ceed6da88864dd77a4
https://eprints.whiterose.ac.uk/165856/1/s41375_020_01022_2.pdf

Phase II study of ISIS 3521, an antisense oligodeoxynucleotide to protein kinase C alpha, in patients with previously treated low-grade non-Hodgkin's lymphoma

Autor: Rao, S., Watkins, D., Cunningham, D. ^*, Dunlop, D., Johnson, P., Selby, P., Hancock, B.W., Fegan, C., Culligan, D., Schey, S., Morris, T.C.M., Lissitchkov, T., Oliver, J.W., Holmlund, J.T.

Publikováno v: In Annals of Oncology September 2004 15(9):1413-1418

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Interim results of a UK NCRI randomised trial comparing involved field radiotherapy with no further treatment after 3 cycles ABVD and a negative PET scan in clinical stages IA/IIA Hodgkin lymphoma

Autor: John Radford, Barrington, S. F., Doherty, M. J. O., Qian, W., Mouncey, P., Pettengell, R., Peter Hoskin, Bessell, E. M., Coltart, R. S., Cunningham, D., Culligan, D., Hatton, C., Johnson, P. W. M., Kruger, A., Linch, D., Lister, T. A., Marcus, R., Sadullah, S., Wimperis, J., Hancock, B. W., Tim Illidge, Pet, Collaborators

Publikováno v: University of Manchester-PURE
ResearcherID

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0c718932b227afef8962911238304785
https://ora.ox.ac.uk/objects/uuid:41c9c119-7444-4551-92c1-98a979ddd6df