Urinary 8-isoprostane levels and occurrence of lung, colorectal, prostate, breast and overall cancer: Results from a large, population-based cohort study with 14 years of follow-up

Autor: Gào, Xīn, Brenner, Hermann, Holleczek, Bernd, Cuk, Katarina, Zhang, Yan, Anusruti, Ankita, Xuan, Yang, Xu, Yiwei, Schöttker, Ben

Publikováno v: In Free Radical Biology and Medicine 1 August 2018 123:20-26

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E-cadherin breast tumor expression, risk factors and survival:Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium

Autor: Horne, Hisani N., Oh, Hannah, Sherman, Mark E., Palakal, Maya, Hewitt, Stephen M., Schmidt, Marjanka K., Milne, Roger L., Hardisson, David, Benitez, Javier, Blomqvist, Carl, Bolla, Manjeet K., Brenner, Hermann, Chang-Claude, Jenny, Cora, Renata, Couch, Fergus J., Cuk, Katarina, Devilee, Peter, Easton, Douglas F., Eccles, Diana M., Eilber, Ursula, Hartikainen, Jaana M., Heikkilä, Päivi, Holleczek, Bernd, Hooning, Maartje J., Jones, Michael, Keeman, Renske, Mannermaa, Arto, Martens, John W. M., Muranen, Taru A., Nevanlinna, Heli, Olson, Janet E., Orr, Nick, Perez, Jose I. A., Pharoah, Paul D. P., Ruddy, Kathryn J., Saum, Kai-Uwe, Schoemaker, Minouk J., Seynaeve, Caroline, Sironen, Reijo, Smit, Vincent T. H. B. M., Swerdlow, Anthony J., Tengström, Maria, Thomas, Abigail S., Timmermans, A. Mieke, Tollenaar, Rob A. E. M., Troester, Melissa A., van Asperen, Christi J., van Deurzen, Carolien H. M., Van Leeuwen, Flora F., Van’t Veer, Laura J., García-Closas, Montserrat, Figueroa, Jonine D.

Publikováno v: Horne, H N, Oh, H, Sherman, M E, Palakal, M, Hewitt, S M, Schmidt, M K, Milne, R L, Hardisson, D, Benitez, J, Blomqvist, C, Bolla, M K, Brenner, H, Chang-Claude, J, Cora, R, Couch, F J, Cuk, K, Devilee, P, Easton, D F, Eccles, D M, Eilber, U, Hartikainen, J M, Heikkilä, P, Holleczek, B, Hooning, M J, Jones, M, Keeman, R, Mannermaa, A, Martens, J W M, Muranen, T A, Nevanlinna, H, Olson, J E, Orr, N, Perez, J I A, Pharoah, P D P, Ruddy, K J, Saum, K-U, Schoemaker, M J, Seynaeve, C, Sironen, R, Smit, V T H B M, Swerdlow, A J, Tengström, M, Thomas, A S, Timmermans, A M, Tollenaar, R A E M, Troester, M A, van Asperen, C J, van Deurzen, C H M, Van Leeuwen, F F, Van't Veer, L J, García-Closas, M & Figueroa, J D 2018, ' E-cadherin breast tumor expression, risk factors and survival : Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium ', Scientific Reports, vol. 8, no. 1, pp. 6574 . https://doi.org/10.1038/s41598-018-23733-4
Scientific Reports
Scientific Reports, 8
Scientific Reports, 8:6574. Nature Publishing Group
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Repisalud
Instituto de Salud Carlos III (ISCIII)

E-cadherin (CDH1) is a putative tumor suppressor gene implicated in breast carcinogenesis. Yet, whether risk factors or survival differ by E-cadherin tumor expression is unclear. We evaluated E-cadherin tumor immunohistochemistry expression using tis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7a15d908e390c620a8b1c9cd1618ecf
https://hdl.handle.net/20.500.11820/40b63bc4-5fed-4c94-b61a-cec4b1e36660

Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants

Autor: Dadaev, Tokhir, Saunders, Edward J., Newcombe, Paul J., Anokian, Ezequiel, Leongamornlert, Daniel A., Brook, Mark N., Cieza-Borrella, Clara, Mijuskovic, Martina, Wakerell, Sarah, Olama, Ali Amin Al, Schumacher, Fredrick R., Berndt, Sonja I., Benlloch, Sara, Ahmed, Mahbubl, Goh, Chee, Sheng, Xin, Zhang, Zhuo, Muir, Kenneth, Govindasami, Koveela, Lophatananon, Artitaya, Stevens, Victoria L., Gapstur, Susan M., Carter, Brian D., Tangen, Catherine M., Goodman, Phyllis, Thompson, Ian M., Batra, Jyotsna, Chambers, Suzanne, Moya, Leire, Clements, Judith, Horvath, Lisa, Tilley, Wayne, Risbridger, Gail, Gronberg, Henrik, Aly, Markus, Nordström, Tobias, Pharoah, Paul, Pashayan, Nora, Schleutker, Johanna, Tammela, Teuvo L.J., Sipeky, Csilla, Auvinen, Anssi, Albanes, Demetrius, Weinstein, Stephanie, Wolk, Alicja, Hakansson, Niclas, West, Catharine, Dunning, Alison M., Burnet, Neil, Mucci, Lorelei, Giovannucci, Edward, Andriole, Gerald, Cussenot, Olivier, Cancel-Tassin, Géraldine, Koutros, Stella, Freeman, Laura E.Beane, Sorensen, Karina Dalsgaard, Orntoft, Torben Falck, Borre, Michael, Maehle, Lovise, Grindedal, Eli Marie, Neal, David E., Donovan, Jenny L., Hamdy, Freddie C., Martin, Richard M., Travis, Ruth C., Key, Tim J., Hamilton, Robert J., Fleshner, Neil E., Finelli, Antonio, Ingles, Sue Ann, Stern, Mariana C., Rosenstein, Barry, Kerns, Sarah, Ostrer, Harry, Lu, Yong Jie, Zhang, Hong Wei, Feng, Ninghan, Mao, Xueying, Guo, Xin, Wang, Guomin, Sun, Zan, Giles, Graham G., Southey, Melissa C., MacInnis, Robert J., Fitzgerald, Liesel M., Kibel, Adam S., Drake, Bettina F., Vega, Ana, Gómez-Caamaño, Antonio, Fachal, Laura, Szulkin, Robert, Eklund, Martin, Kogevinas, Manolis, Llorca, Javier, Castaño-Vinyals, Gemma, Penney, Kathryn L., Stampfer, Meir, Park, Jong Y., Sellers, Thomas A., Lin, Hui Yi, Stanford, Janet L., Cybulski, Cezary, Wokolorczyk, Dominika, Lubinski, Jan, Ostrander, Elaine A., Geybels, Milan S., Nordestgaard, Børge G., Nielsen, Sune F., Weisher, Maren, Bisbjerg, Rasmus, Røder, Martin Andreas, Iversen, Peter, Brenner, Hermann, Cuk, Katarina, Holleczek, Bernd, Maier, Christiane, Luedeke, Manuel, Schnoeller, Thomas, Kim, Jeri, Logothetis, Christopher J., John, Esther M., Teixeira, Manuel R., Paulo, Paula, Cardoso, Marta, Neuhausen, Susan L., Steele, Linda, Ding, Yuan Chun, De Ruyck, Kim, De Meerleer, Gert, Ost, Piet, Razack, Azad, Lim, Jasmine, Teo, Soo Hwang, Lin, Daniel W., Newcomb, Lisa F., Lessel, Davor, Gamulin, Marija, Kulis, Tomislav, Kaneva, Radka, Usmani, Nawaid, Slavov, Chavdar, Mitev, Vanio, Parliament, Matthew, Singhal, Sandeep, Claessens, Frank, Joniau, Steven, Van Den Broeck, Thomas, Larkin, Samantha, Townsend, Paul A., Aukim-Hastie, Claire, Gago-Dominguez, Manuela, Castelao, Jose Esteban, Martinez, Maria Elena, Roobol, Monique J., Jenster, Guido, Van Schaik, Ron H.N., Menegaux, Florence, Truong, Thérèse, Koudou, Yves Akoli, Xu, Jianfeng, Khaw, Kay Tee, Cannon-Albright, Lisa, Pandha, Hardev, Michael, Agnieszka, Kierzek, Andrzej, Thibodeau, Stephen N., McDonnell, Shannon K., Schaid, Daniel J., Lindstrom, Sara, Turman, Constance, Ma, Jing, Hunter, David J., Riboli, Elio, Siddiq, Afshan, Canzian, Federico, Kolonel, Laurence N., Le Marchand, Loic, Hoover, Robert N., Machiela, Mitchell J., Kraft, Peter, Cook, Margaret, Thwaites, Alison, Guy, Michelle, Whitmore, Ian, Morgan, Angela, Fisher, Cyril, Hazel, Steve, Livni, Naomi, Spurdle, Amanda, Srinivasan, Srilakshmi, Kedda, Mary Anne, Aitken, Joanne, Gardiner, Robert, Hayes, Vanessa, Butler, Lisa, Taylor, Renea, Yeadon, Trina, Eckert, Allison, Saunders, Pamela, Haynes, Anne Maree, Papargiris, Melissa, Kujala, Paula, Talala, Kirsi, Murtola, Teemu, Taari, Kimmo, Dearnaley, David, Barnett, Gill, Bentzen, Søren, Elliott, Rebecca, Ranu, Hardeep, Hicks, Belynda, Vogt, Aurelie, Hutchinson, Amy, Cox, Angela, Davis, Michael, Brown, Paul, George, Anne, Marsden, Gemma, Lane, Athene, Lewis, Sarah J., Berry, Clare, Kulkarni, Girish S., Toi, Ants, Evans, Andrew, Zlotta, Alexandre R., Van Der Kwast, Theodorus H., Imai, Takashi, Saito, Shiro, Marzec, Jacek, Cao, Guangwen, Lin, Ji, Ling, Jin, Li, Meiling, Zhao, Shan Chao, Ren, Guoping, Yu, Yongwei, Wu, Yudong, Wu, Ji, Zhou, Bo, Zhang, Yangling, Li, Jie, He, Weiyang, Guo, Jianming, Pedersen, John, Hopper, John L., Milne, Roger, Klim, Aleksandra, Carballo, Ana, Lobato-Busto, Ramón, Peleteiro, Paula, Calvo, Patricia, Aguado, Miguel, Ruiz-Dominguez, José Manuel, Cecchini, Lluís, Mengual, Lourdes, Alcaraz, Antonio, Bustamante, Mariona, Gracia-Lavedan, Esther, Dierssen-Sotos, Trinidad, Gomez-Acebo, Ines, Pow-Sang, Julio, Park, Hyun, Zachariah, Babu, Kluzniak, Wojciech, Kolb, Suzanne, Klarskov, Peter, Stegmaier, Christa, Vogel, Walther, Herkommer, Kathleen, Bohnert, Philipp, Maia, Sofia, Silva, Maria P., De Langhe, Sofie, Thierens, Hubert, Tan, Meng H., Ong, Aik T., Kastelan, Zeljko, Popov, Elenko, Kachakova, Darina, Mitkova, Atanaska, Vlahova, Aleksandrina, Dikov, Tihomir, Christova, Svetlana, Carracedo, Angel, Bangma, Christopher, Schroder, F. H., Cenee, Sylvie, Tretarre, Brigitte, Rebillard, Xavier, Mulot, Claire, Sanchez, Marie, Adolfsson, Jan, Stattin, Par, Johansson, Jan Erik, Cavalli-Bjoerkman, Carin, Karlsson, Ami, Broms, Michael, Wu, Huihai, Tillmans, Lori, Riska, Shaun, Freedman, Matthew, Wiklund, Fredrik, Chanock, Stephen, Henderson, Brian E., Easton, Douglas F., Haiman, Christopher A., Eeles, Rosalind A., Conti, David V., Kote-Jarai, Zsofia

Publikováno v: Dadaev, T, Saunders, E J, Newcombe, P J, Anokian, E, Leongamornlert, D A, Brook, M N, Cieza-Borrella, C, Mijuskovic, M, Wakerell, S, Olama, A A A, Schumacher, F R, Berndt, S I, Benlloch, S, Ahmed, M, Goh, C, Sheng, X, Zhang, Z, Muir, K, Govindasami, K, Lophatananon, A, Stevens, V L, Gapstur, S M, Carter, B D, Tangen, C M, Goodman, P, Thompson, I M, Batra, J, Chambers, S, Moya, L, Clements, J, Horvath, L, Tilley, W, Risbridger, G, Gronberg, H, Aly, M, Nordström, T, Pharoah, P, Pashayan, N, Schleutker, J, Tammela, T L J, Sipeky, C, Auvinen, A, Albanes, D, Weinstein, S, Wolk, A, Hakansson, N, West, C, Dunning, A M, Burnet, N, Mucci, L, Giovannucci, E, Andriole, G, Cussenot, O, Cancel-Tassin, G, Koutros, S, Freeman, L E B, Sorensen, K D, Orntoft, T F, Borre, M, Maehle, L, Grindedal, E M, Neal, D E, Donovan, J L, Hamdy, F C, Martin, R M, Travis, R C, Key, T J, Hamilton, R J, Fleshner, N E, Finelli, A, Ingles, S A, Stern, M C, Rosenstein, B, Kerns, S, Ostrer, H, Lu, Y J, Zhang, H W, Feng, N, Mao, X, Guo, X, Wang, G, Sun, Z, Giles, G G, Southey, M C, MacInnis, R J, Fitzgerald, L M, Kibel, A S, Drake, B F, Vega, A, Gómez-Caamaño, A, Fachal, L, Szulkin, R, Eklund, M, Kogevinas, M, Llorca, J, Castaño-Vinyals, G, Penney, K L, Stampfer, M, Park, J Y, Sellers, T A, Lin, H Y, Stanford, J L, Cybulski, C, Wokolorczyk, D, Lubinski, J, Ostrander, E A, Geybels, M S, Nordestgaard, B G, Nielsen, S F, Weisher, M, Bisbjerg, R, Røder, M A, Iversen, P, Brenner, H, Cuk, K, Holleczek, B, Maier, C, Luedeke, M, Schnoeller, T, Kim, J, Logothetis, C J, John, E M, Teixeira, M R, Paulo, P, Cardoso, M, Neuhausen, S L, Steele, L, Ding, Y C, De Ruyck, K, De Meerleer, G, Ost, P, Razack, A, Lim, J, Teo, S H, Lin, D W, Newcomb, L F, Lessel, D, Gamulin, M, Kulis, T, Kaneva, R, Usmani, N, Slavov, C, Mitev, V, Parliament, M, Singhal, S, Claessens, F, Joniau, S, Van Den Broeck, T, Larkin, S, Townsend, P A, Aukim-Hastie, C, Gago-Dominguez, M, Castelao, J E, Martinez, M E, Roobol, M J, Jenster, G, Van Schaik, R H N, Menegaux, F, Truong, T, Koudou, Y A, Xu, J, Khaw, K T, Cannon-Albright, L, Pandha, H, Michael, A, Kierzek, A, Thibodeau, S N, McDonnell, S K, Schaid, D J, Lindstrom, S, Turman, C, Ma, J, Hunter, D J, Riboli, E, Siddiq, A, Canzian, F, Kolonel, L N, Le Marchand, L, Hoover, R N, Machiela, M J, Kraft, P, Cook, M, Thwaites, A, Guy, M, Whitmore, I, Morgan, A, Fisher, C, Hazel, S, Livni, N, Spurdle, A, Srinivasan, S, Kedda, M A, Aitken, J, Gardiner, R, Hayes, V, Butler, L, Taylor, R, Yeadon, T, Eckert, A, Saunders, P, Haynes, A M, Papargiris, M, Kujala, P, Talala, K, Murtola, T, Taari, K, Dearnaley, D, Barnett, G, Bentzen, S, Elliott, R, Ranu, H, Hicks, B, Vogt, A, Hutchinson, A, Cox, A, Davis, M, Brown, P, George, A, Marsden, G, Lane, A, Lewis, S J, Berry, C, Kulkarni, G S, Toi, A, Evans, A, Zlotta, A R, Van Der Kwast, T H, Imai, T, Saito, S, Marzec, J, Cao, G, Lin, J, Ling, J, Li, M, Zhao, S C, Ren, G, Yu, Y, Wu, Y, Wu, J, Zhou, B, Zhang, Y, Li, J, He, W, Guo, J, Pedersen, J, Hopper, J L, Milne, R, Klim, A, Carballo, A, Lobato-Busto, R, Peleteiro, P, Calvo, P, Aguado, M, Ruiz-Dominguez, J M, Cecchini, L, Mengual, L, Alcaraz, A, Bustamante, M, Gracia-Lavedan, E, Dierssen-Sotos, T, Gomez-Acebo, I, Pow-Sang, J, Park, H, Zachariah, B, Kluzniak, W, Kolb, S, Klarskov, P, Stegmaier, C, Vogel, W, Herkommer, K, Bohnert, P, Maia, S, Silva, M P, De Langhe, S, Thierens, H, Tan, M H, Ong, A T, Kastelan, Z, Popov, E, Kachakova, D, Mitkova, A, Vlahova, A, Dikov, T, Christova, S, Carracedo, A, Bangma, C, Schroder, F H, Cenee, S, Tretarre, B, Rebillard, X, Mulot, C, Sanchez, M, Adolfsson, J, Stattin, P, Johansson, J E, Cavalli-Bjoerkman, C, Karlsson, A, Broms, M, Wu, H, Tillmans, L, Riska, S, Freedman, M, Wiklund, F, Chanock, S, Henderson, B E, Easton, D F, Haiman, C A, Eeles, R A, Conti, D V & Kote-Jarai, Z 2018, ' Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants ', Nature Communications, vol. 9, no. 1, 2256 . https://doi.org/10.1038/s41467-018-04109-8

Prostate cancer is a polygenic disease with a large heritable component. A number of common, low-penetrance prostate cancer risk loci have been identified through GWAS. Here we apply the Bayesian multivariate variable selection algorithm JAM to fine-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::29de179b88c5a5d43817d22edb744167
https://acuresearchbank.acu.edu.au/item/8x556/fine-mapping-of-prostate-cancer-susceptibility-loci-in-a-large-meta-analysis-identifies-candidate-causal-variants