Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Cuiyun Li"'
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundThis study aims to investigate the underlying characteristics of spontaneous brain activity by analyzing the volumes of the hippocampus and parahippocampal gyrus, as well as the fractional amplitude of low-frequency fluctuation (fALFF) and
Externí odkaz:
https://doaj.org/article/da01b02c85184f9f97617b89d2a2d4f9
Autor:
Jia Xu, Hong Zhang, Hong Chen, Xiaoxue Zhu, Haiyan Jia, Zhongnan Xu, Dandan Huo, Cuiyun Li, Yanhua Ding
Publikováno v:
Annals of Medicine, Vol 55, Iss 2 (2023)
AbstractBackground: TQA3526 is a novel farnesoid X receptor agonist developed to treat non-alcoholic steatohepatitis (NASH) or primary biliary cholangitis (PBC). This study aimed to evaluate the safety, tolerability, pharmacokinetics (PK), and pharma
Externí odkaz:
https://doaj.org/article/21c9bbece98d4361bc32077cb24b1fdd
Autor:
Cuiyun Li, Min Wu, Hong Zhang, Xiaoxue Zhu, Li Fu, Shuo Wang, Mingming Lu, Dafang Zhong, Yanhua Ding
Publikováno v:
Annals of Medicine, Vol 55, Iss 2 (2023)
AbstractBackground Forsythin, an active compound from Forsythiae Fructus, has the potential to treat the common cold and influenza through its antipyretic-analgesic, anti-inflammatory and antiviral effects. The safety, tolerability and pharmacokineti
Externí odkaz:
https://doaj.org/article/e01418cc159b4eae9a69954eff4379ed
Autor:
Haiyan Jia, Jiajia Mai, Min Wu, Hong Chen, Xiaojiao Li, Cuiyun Li, Jingrui Liu, Chengjiao Liu, Yue Hu, Xiaoxue Zhu, Xiuhong Jiang, Bo Hua, Tian Xia, Gang Liu, Aiyun Deng, Bo Liang, Ruoling Guo, Hui Lu, Zhe Wang, Huanming Chen, Zhijun Zhang, Hong Zhang, Junqi Niu, Yanhua Ding
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Hepatitis B virus (HBV) core protein-targeting antivirals (CpTAs) are promising therapeutic agents for treating chronic hepatitis B (CHB). In this study, the antiviral activity, pharmacokinetics (PK), and tolerability of ZM-H1505R
Externí odkaz:
https://doaj.org/article/02bce6f28a1643cd90afd9d651ebfed5
Autor:
Yue Hu, Xiaojiao Li, Jingrui Liu, Hong Chen, Wenbo Zheng, Hong Zhang, Min Wu, Cuiyun Li, Xiaoxue Zhu, Jinfeng Lou, Pangke Yan, Nan Wu, Xiao Liu, Shiping Ma, Xu Wang, Yanhua Ding, Chengluan Xuan
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 2758-2769 (2022)
Background The primary objective of this study was to investigate if hepatic impairment alters the safety, pharmacokinetics, and pharmacodynamics of HSK3486.Research design and methods This was a clinical trial of HSK3486 in subjects with normal hepa
Externí odkaz:
https://doaj.org/article/47b2fb3c1cea48198dbee99496937eed
Publikováno v:
European Journal of Inflammation, Vol 21 (2023)
Objectives Phytic acid (PYT) also known as inositol hexakisphosphate or inositol polyphosphate has shown a broad range of biological effects including anti-inflammatory, antioxidant, and anticancer effects in several preclinical studies. This study a
Externí odkaz:
https://doaj.org/article/4ee0771eaea64305a0e90168e7e470f4
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Psychological distress (depression, anxiety and stress) is more common among medical students than in the general population, and is an important cause of insomnia, internet addiction, substance abuse, decreased academic performan
Externí odkaz:
https://doaj.org/article/623db282258647f4ab36f8e25a5e3fcf
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
SATB1 variants causing developmental delay with dysmorphic facies and dental anomalies have been reported in a small cohort. Most patients present epilepsy as a main clinical feature in neurodevelopmental disorders; however, its treatment is unknown.
Externí odkaz:
https://doaj.org/article/6695d2e8527e49039acdfdad2da4fecd
Autor:
Ying Yu, Chunjiao Lu, Ying Gao, Cuiyun Li, Dongxue Li, Jie Wang, Hui Wei, Zhaohui Lu, Guoling You
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundThalassemia is one of the most common genetic diseases in southern China. Accurate population frequency data regarding the occurrence and distribution of thalassemia are important for designing appropriate prevention strategies for thalasse
Externí odkaz:
https://doaj.org/article/82a31b28263d457ea603e90b167f6998
Autor:
Hong Zhang, Xiaojiao Li, Jingrui Liu, Cuiyun Li, Min Wu, Xiaoxue Zhu, Jixuan Sun, Min Fang, Yanhua Ding
Publikováno v:
Annals of Medicine, Vol 53, Iss 1, Pp 375-383 (2021)
AbstractPurpose QX003S is a biosimilar candidate for the reference tocilizumab, Actemra®. We investigated the tolerance, variability, and pharmacokinetics (PK) of QX003S biosimilar in healthy Chinese male subjects.Design A randomised, double-blind,
Externí odkaz:
https://doaj.org/article/d226eed6d169454286b7c306314fa8f9