Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Cuiyong Yue"'
Autor:
Joseph F. Merola, April Armstrong, Saakshi Khattri, So Yeon Paek, Byron Padilla, Cuiyong Yue, Huzefa Photowala, Blair Kaplan, Lars Erik Kristensen
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
AbstractIn the KEEPsAKE 1 (NCT03675308) and KEEPsAKE 2 (NCT03671148) phase 3 trials, risankizumab demonstrated greater efficacy compared with placebo in patients with active psoriatic arthritis (PsA). This post hoc integrated analysis evaluated achie
Externí odkaz:
https://doaj.org/article/39e61f6277034f2f88e208b5a6fe086b
Autor:
Merola, Joseph F., Armstrong, April, Khattric, Saakshi, So Yeon Paekd, Padilla, Byron, Cuiyong Yue, Photowala, Huzefa, Kaplan, Blair, Kristensen, Lars Erik
Publikováno v:
Journal of Dermatological Treatment; Dec2024, Vol. 35 Issue 1, p1-10, 10p
Publikováno v:
Brain
Temporal lobe epilepsy is associated with significant structural pathology in the hippocampus. In the dentate gyrus, the summative effect of these pathologies is massive hyperexcitability in the granule cells, generating both increased seizure suscep
Autor:
Zhuohao He, Kurt R. Brunden, Ted Abel, Jennifer D. McBride, Sneha Narasimhan, Magdalena Nitla, Lakshmi Changolkar, Jing L. Guo, Ronald J. Gathagan, John Q. Trojanowski, Hyesung Kim, Virginia M.-Y. Lee, Douglas A. Coulter, Anna Stieber, Cuiyong Yue, Bin Zhang, Christopher G. Dengler
Publikováno v:
Nature Medicine. 24:29-38
Alzheimer’s disease (AD) is characterized by extracellular amyloid-β (Aβ) plaques and intracellular tau inclusions. However, the exact mechanistic link between these two AD lesions remains enigmatic. Through injection of human AD-brain-derived pa
Autor:
Jun Y. Lee, Barbara Terzic, Zhaolan Zhou, Sheng Tang, Hajime Takano, Douglas A. Coulter, Katarina Pance, I-Ting Judy Wang, Cuiyong Yue, Yue Cui
Cyclin-dependent kinase-like 5 (CDKL5) deficiency is a neurodevelopmental disorder characterized by epileptic seizures, severe intellectual disability, and autistic features. Mice lacking CDKL5 display multiple behavioral abnormalities reminiscent of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e32eb2b1f2f3a5682acf00b5d90821a
https://europepmc.org/articles/PMC5546111/
https://europepmc.org/articles/PMC5546111/
Autor:
David F. Meaney, John H. Wolfe, Hayley C. Anderson, Hajime Takano, Douglas A. Coulter, Cuiyong Yue, Tanya N Weerakkody, Tapan P. Patel
Publikováno v:
Molecular Therapy. 21(12):2258-2267
Neural stem cell (NSC) therapy represents a potentially powerful approach for gene transfer in the diseased central nervous system. However, transplanted primary, embryonic stem cell- and induced pluripotent stem cell-derived NSCs generate largely un
Autor:
Esther P. Yu, Mary E. Putt, Hajime Takano, Christopher G. Dengler, Shanti F. Frausto, Cuiyong Yue, Douglas A. Coulter
Publikováno v:
The Journal of Neuroscience. 33:2947-2960
The dentate gyrus (DG) is a critical entry point regulating function of the hippocampus. Integral to this role are the sparse, selective activation characteristics of the principal cells of the DG, dentate granule cells (DGCs). This sparse activation
Publikováno v:
Scientific Reports
In a mouse model of temporal lobe epilepsy, multicellular calcium imaging revealed that disease emergence was accompanied by massive amplification in the normally sparse, afferent stimulation-induced activation of hippocampal dentate granule cells. P
Autor:
Florian Weissinger, Cuiyong Yue, Chyze Whee Ang, Fu-Chun Hsu, Hajime Takano, Douglas A. Coulter, Ethan M. Goldberg, Gregory C. Carlson
Publikováno v:
The Journal of Physiology. 589:1893-1903
Mammalian cortical structures are endowed with the capacity for plasticity, which emerges from a combination of the dynamics of circuit connectivity and function, and the intrinsic function of the neurons within the circuit. However, this capacity is
Autor:
Cuiyong Yue, Alison E. Mungenast, Philip G. Haydon, Jinghui Dong, Douglas A. Coulter, Hajime Takano, Deborah Watson, Pavel I. Ortinski
Publikováno v:
Nature neuroscience
Reactive astrocytosis develops in many neurologic diseases, including epilepsy. Astrocytotic contributions to pathophysiology are poorly understood. Studies examining this are confounded by comorbidities accompanying reactive astrocytosis. We found t