Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Cuiyan Xin"'
Autor:
Gautam Kundu, Maryam Ghasemi, Seungbin Yim, Ayanna Rohil, Cuiyan Xin, Leo Ren, Shraddha Srivastava, Akinwande Akinfolarin, Subodh Kumar, Gyan P. Srivastava, Venkata S. Sabbisetti, Gopal Murugaiyan, Amrendra K. Ajay
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2102 (2024)
Background: Signal transducer and activator of transcription 3 (STAT3) is a member of the cytoplasmic inducible transcription factors and plays an important role in mediating signals from cytokines, chemokines, and growth factors. We and others have
Externí odkaz:
https://doaj.org/article/1cf84321216f4f3fa08d8e61780970cb
Autor:
Cuiyan Xin, Jiahui Lei, Qian Wang, Yixia Yin, Xiaoqian Yang, Jose Alberto Moran Guerrero, Venkata Sabbisetti, Xiaoming Sun, Vishal S. Vaidya, Joseph V. Bonventre
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103193- (2021)
Summary: Chronic kidney disease (CKD) is associated with substantial morbidity and mortality. We developed a mouse model that mimics human CKD with inflammation, extracellular matrix deposition, tubulointerstitial fibrosis, increased proteinuria, and
Externí odkaz:
https://doaj.org/article/0191900a45db43debe2d94491ac0a6ab
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 9, Pp 1985-1996 (2007)
Sphingosylphosphorylcholine (SPC) is a bioactive lipid that binds to G protein-coupled-receptors and activates various signaling cascades. Here, we show that in renal mesangial cells, SPC not only activates various protein kinase cascades but also ac
Externí odkaz:
https://doaj.org/article/392cf8e61ec8464dac51a486d0aabc3d
Autor:
Eoin D. O’Sullivan, Katie J. Mylonas, Cuiyan Xin, David P. Baird, Cyril Carvalho, Marie-Helena Docherty, Ross Campbell, Kylie P. Matchett, Scott H. Waddell, Alexander D. Walker, Kevin M. Gallagher, Siyang Jia, Steve Leung, Alexander Laird, Julia Wilflingseder, Michaela Willi, Maximilian Reck, Sarah Finnie, Angela Pisco, Sabrina Gordon-Keylock, Alexander Medvinsky, Luke Boulter, Neil C. Henderson, Kristina Kirschner, Tamir Chandra, Bryan R. Conway, Jeremy Hughes, Laura Denby, Joseph V. Bonventre, David A. Ferenbach
Publikováno v:
Science Translational Medicine. 15
Progressive fibrosis is a feature of aging and chronic tissue injury in multiple organs, including the kidney and heart. Glioma-associated oncogene 1 expressing (Gli1 + ) cells are a major source of activated fibroblasts in multiple organs, but the l
Autor:
Cuiyan Xin, Bryan R. Conway, Sarah Finnie, Joseph V. Bonventre, Laura Denby, Cyril Carvalho, Julia Wilflingseder, Neil Henderson, Jeremy Hughes, Eoin O'Sullivan, Angela Oliveira Pisco, Michaela Willi, Katie J. Mylonas, David A. Ferenbach
Chronic kidney disease (CKD) and ageing inhibit tissue regeneration and increase risks of organ fibrosis and cardiovascular disease. Increased numbers of leukocytes are present in the circulation and within the kidney of ageing individuals and patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4615b28a91782b677f72a3c9921f9261
https://doi.org/10.21203/rs.3.rs-793155/v1
https://doi.org/10.21203/rs.3.rs-793155/v1
Autor:
Cuiyan Xin, Naoki Nakagawa, Allie M. Roach, Stuart J. Shankland, Giovanni Ligresti, Natalie Naiman, Suzanne Szak, Ivan G. Gomez, Jeremy S. Duffield, Shuyu Ren
Publikováno v:
Kidney International. 87:1125-1140
MicroRNAs, activated by the enzyme Dicer1, control post-transcriptional gene expression. Dicer1 has important roles in the epithelium during nephrogenesis, but its function in stromal cells during kidney development is unknown. To study this, we inac
Autor:
Cuiyan Xin1, Shuyu Ren1, Eberhardt, Wolfgang1, Pfeilschifter, Josef1, Huwiler, Andrea1 Huwiler@em.uni-frankfurt.de
Publikováno v:
British Journal of Pharmacology. Jan2006, Vol. 147 Issue 2, p164-174. 11p.
Publikováno v:
British Journal of Pharmacology. Nov2004, Vol. 143 Issue 5, p581-589. 9p.
Publikováno v:
British Journal of Pharmacology. Feb2003, Vol. 138 Issue 3, p461. 8p.
Autor:
Sean E. Gill, Cuiyan Xin, George E. Davis, Jeremy S. Duffield, Benjamin D. Humphreys, Shuei-Liong Lin, Claudia Schrimpf, Gabriella Campanholle, William B. Stallcup, Sina A. Gharib
Publikováno v:
Journal of the American Society of Nephrology. 23:868-883
Kidney pericytes are progenitors of scar-forming interstitial myofibroblasts that appear after injury. The function of kidney pericytes as microvascular cells and how these cells detach from peritubular capillaries and migrate to the interstitial spa