PCV2 replication promoted by oxidative stress is dependent on the regulation of autophagy on apoptosis

Autor: Nianhui Zhai, Kai Liu, Hu Li, Zixuan Liu, Hong Wang, Viktor I. Korolchuk, Bernadette Carroll, Cuiling Pan, Fang Gan, Kehe Huang, Xingxiang Chen

Publikováno v: Veterinary Research, Vol 50, Iss 1, Pp 1-11 (2019)

Abstract Porcine circovirus type 2 (PCV2) is an economically important swine pathogen but some extra trigger factors are required for the development of PCV2-associated diseases. By evaluating cap protein expression, viral DNA copies and the number o

Externí odkaz: https://doaj.org/article/32b98866c0a749698d2c641a62a44462

Selenomethionine alleviated Ochratoxin A induced pyroptosis and renal fibrotic factors expressions in MDCK cells

Autor: Lei Ge, Heng Du, Xingxiang Chen, Fang Gan, Hu Li, Shuiping Liu, Yunhuan Liu, Lili Hou, Kehe Huang, Cuiling Pan, Xinru Mao, Dongmei Yue

Publikováno v: Journal of Biochemical and Molecular Toxicology. 36

Ochratoxin A (OTA) is universally known to induce nephrotoxicity via inducing oxidative stress and apoptosis, inhibiting protein synthesis and activating autophagy. Our previous studies have proved that OTA induces nephrotoxicity in vitro and in vivo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56108c4b1dde9710787bc4225b03a36
https://doi.org/10.1002/jbt.22933

PCV2 replication promoted by oxidative stress is dependent on the regulation of autophagy on apoptosis

Autor: Xingxiang Chen, Cuiling Pan, Viktor I. Korolchuk, Fang Gan, Nianhui Zhai, Hu Li, Hong Wang, Bernadette Carroll, Zixuan Liu, Kehe Huang, Kai Liu

Publikováno v: Veterinary Research, Vol 50, Iss 1, Pp 1-11 (2019)
Veterinary Research
Veterinary Research, BioMed Central, 2019, 50 (1), pp.19. ⟨10.1186/s13567-019-0637-z⟩
Zhai, N, Liu, H, Liu, X, Wang, H, Korolchuk, V, Carroll, B, Pan, C, Gan, F, Huang, K & Chen, X 2019, ' PCV2 replication promoted by oxidative stress is dependent on the regulation of autophagy on apoptosis ', Veterinary Research, vol. 50, no. 19, 19 . https://doi.org/10.1186/s13567-019-0637-z

International audience; AbstractPorcine circovirus type 2 (PCV2) is an economically important swine pathogen but some extra trigger factors are required for the development of PCV2-associated diseases. By evaluating cap protein expression, viral DNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7792593072858c7fdee318c5cf2d7d7
http://link.springer.com/article/10.1186/s13567-019-0637-z

Regulation of taurine in OTA-induced apoptosis and autophagy

Autor: Dandan Liu, Cuiling Pan, Xingxiang Chen, Kehe Huang, Xinru Mao, Fang Gan, Kai Liu, Guannan Le, Hu Li

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 181

Ochratoxin A (OTA), one of the most deleterious mycotoxins, could cause a variety of toxicological effects especially nephrotoxicity in animals and humans. Taurine, a wide-distributed cytoprotective amino acid, plays an important role as a basic fact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67727b2606e214cc67f631da47107084
https://pubmed.ncbi.nlm.nih.gov/32371067

Lycium barbarum polysaccharides improve CCl4-induced liver fibrosis, inflammatory response and TLRs/NF-kB signaling pathway expression in wistar rats

Autor: Qing Liu, Cuiling Pan, Yunhuan Liu, Fang Gan, Da Huang, Suquan Song, Kehe Huang

Publikováno v: Life Sciences. 192:205-212

Lycium barbarum polysaccharides (LBPs) have multiple biological and pharmacological functions, including antioxidant, anti-inflammatory and anticancer activities. This research was conducted to evaluate whether LBPs could alleviate carbon tetrachlori

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11cfd30186c0068a13d3abd95e8f1eb1
https://doi.org/10.1016/j.lfs.2017.11.047