Autologous Cytokine-Induced Killer Cell Immunotherapy Enhances Chemotherapy Efficacy against Multidrug-Resistant Tuberculosis

Autor: Peijun Tang, Xingnian Chen, Junchi Xu, Yunlong Hu, Zhijian Ye, Xiafang Wang, Yumei Xiao, Xinghua Shen, Jianping Zhang, Yanjun Feng, Cuilin Shi, Xin Yu, Lixian Yi, Xinchun Chen, Binfeng Lu, Ping Xu, Zhongwen Sun, Meiying Wu

Publikováno v: Journal of Immunology Research, Vol 2022 (2022)

Objective. Multidrug-resistant tuberculosis (MDR-TB) causes persistent infection and challenges tuberculosis control worldwide. T cell-mediated immunity plays a critical role in controlling Mycobacterium tuberculosis (Mtb) infection, and therefore, e

Externí odkaz: https://doaj.org/article/e7edf10e63a6427ab59c88d017f0f34c

First-line anti-tuberculosis drugs induce hepatotoxicity: A novel mechanism based on a urinary metabolomics platform

Autor: Yicong Bian, Liyan Miao, Cuilin Shi, Linsheng Liu, Yijun Mi, Chenrong Huang, Jun Cao, Zhijian Ye

Publikováno v: Biochemical and Biophysical Research Communications. 497:485-491

Tuberculosis (TB) has become a global public health and social threat. As clinical first-line drugs, rifampicin and isoniazid used in combination with pyrazinamide and ethambutol (the HRZE regimen) usually induce hepatotoxicity. However, the mechanis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2790cce229ecdee3da36edb325ac78
https://doi.org/10.1016/j.bbrc.2018.02.030

Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense

Autor: Zili Zhang, She Chen, Xiaoliang Yu, Lin Li, Xing Wang, Shan Liu, Lin Ge, Qin Chen, Lu Yu, Cuilin Shi, Sudan He, Lei Xu, Zhongxu Yang, Biqi Zhou, Yun Li, Wenhui He, Zhilin Hu, Xuejun Jiang, Jun Li

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 111(43)

The receptor-interacting kinase-3 (RIP3) and its downstream substrate mixed lineage kinase domain-like protein (MLKL) have emerged as the key cellular components in programmed necrotic cell death. Receptors for the cytokines of tumor necrosis factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5500cd0b67a31c8a08467b66eaff93fa
https://pubmed.ncbi.nlm.nih.gov/25674981

Autologous Cytokine-Induced Killer Cell Immunotherapy Enhances Chemotherapy Efficacy against Multidrug-Resistant Tuberculosis.

Autor: Tang, Peijun^1,2 (AUTHOR), Chen, Xingnian¹ (AUTHOR), Xu, Junchi¹ (AUTHOR), Hu, Yunlong^3,4 (AUTHOR), Ye, Zhijian¹ (AUTHOR), Wang, Xiafang¹ (AUTHOR), Xiao, Yumei^1,2 (AUTHOR), Shen, Xinghua¹ (AUTHOR), Zhang, Jianping¹ (AUTHOR), Feng, Yanjun¹ (AUTHOR), Shi, Cuilin¹ (AUTHOR), Yu, Xin¹ (AUTHOR), Yi, Lixian² (AUTHOR), Chen, Xinchun⁴ (AUTHOR), Lu, Binfeng⁵ (AUTHOR), Xu, Ping^1,2 (AUTHOR), Sun, Zhongwen² (AUTHOR), Wu, Meiying¹ (AUTHOR)

Publikováno v: Journal of Immunology Research. 3/17/2022, p1-10. 10p. 1 Black and White Photograph, 7 Charts.

Investigators at Fifth People's Hospital of Suzhou Report Findings in COVID-19 (Oral Liushen Pill for Patients With Covid-19: a Prospective Randomized Controlled Trial).

Publikováno v: NewsRx COVID-19 Weekly; 3/10/2023, p19-19, 1p