Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cuijian Yang"'
Autor:
Richard Eric Mewshaw, James C. Keith, Eric S. Manas, Cuijian Yang, Ruth A. Henderson, Heather A. Harris, Richard James Edsall, Zhang B. Xu
Publikováno v:
Journal of Medicinal Chemistry. 48:3953-3979
The 2-phenylnaphthalene scaffold was explored as a simplified version of genistein in order to identify ER selective ligands. With the aid of docking studies, positions 1, 4, and 8 of the 2-phenylnaphthalene template were predicted to be the most pot
Autor:
Cuijian Yang, Rong Xu, Hong Tsao, Tongming Liu, Nicholas E. Geacintov, Shantu Amin, Bin Li, Masaaki Moriya, Jing Xu
Publikováno v:
Chemical Research in Toxicology. 9:255-261
A metabolite of the pollutant benzopyrene r7,t8-dihydroxy-t9,10-epoxy-7,8,9,10-tetrahydrobenzopyrene (racemic plus and minus anti-BPDE), has been shown to be mutagenic. In order to elucidate the structural features of adduct derived from the binding
Publikováno v:
Journal of Carbohydrate Chemistry. 11:379-395
The title 1,3-anhydro sugar (9) was synthesized from methyl α-D-fucopyranoside in 7 steps, most of which were carried out readily in high yield. The key intermediate for the synthesis was 3-O-acetyl-2,4-di-O-benzyl-α-D-fucopyranosyl chloride (7), w
Autor:
John W. Ullrich, Igor Goljer, Joseph T. Lundquist, Matthew L. Crawley, John F. Mehlmann, Kristin M. Phipps, Cuijian Yang, Paige Erin Mahaney
Publikováno v:
ChemInform. 40
An efficient and mild method to couple aryl bromides and activated non-allylic alcohols in a Heck reaction with tandem isomerization to selectively afford high yields of 1,5-diarylalkan-1-ones has been developed. Mechanistic insight was gained throug
Autor:
John F. Mehlmann, Paige Erin Mahaney, Igor Goljer, Joseph T. Lundquist, Kristin M. Phipps, Cuijian Yang, Matthew L. Crawley, John W. Ullrich
Publikováno v:
Organic letters. 11(5)
An efficient and mild method to couple aryl bromides and activated non-allylic alcohols in a Heck reaction with tandem isomerization to selectively afford high yields of 1,5-diarylalkan-1-ones has been developed. Mechanistic insight was gained throug
Autor:
Richard Eric Mewshaw, Xiaochun Zhang, Cuijian Yang, Heather A. Harris, Eric S. Manas, Richard James Edsall
Publikováno v:
Bioorganicmedicinal chemistry. 12(10)
A series of biphenyl carbaldehyde oximes (6) was prepared and shown to have significant selectivity for the estrogen receptor-beta (ERbeta). The exploitation of the oxime moiety as a hydrogen bond donating group, which mimicked the C-ring of genistei
Autor:
Matthew L. Crawley, Kristin M. Phipps, Igor Goljer, John F. Mehlmann, Joseph T. Lundquist, John W. Ullrich, Cuijian Yang, Paige E. Mahaney
Publikováno v:
Organic Letters; Mar2009, Vol. 11 Issue 5, p1183-1185, 3p