Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Cuige Zhu"'
Autor:
Cuige Zhu, Mari Iwase, Ziqian Li, Faliang Wang, Annabel Quinet, Alessandro Vindigni, Jieya Shao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Subcellular localization plays an important yet underappreciated role in protein functions. Here the authors defined novel and context-dependent nuclear functions of the actin-binding factor profilin-1 in DNA replication fork dynamics and stability.
Externí odkaz:
https://doaj.org/article/8e3bb79d1a6a4af6ad2fc1cd8895c484
Autor:
Guoshuai Feng, Cuige Zhu, Chieh‐Yu Lin, Andrea Bredemeyer, Irmgard Förster, Daniel Kreisel, Kory J. Lavine
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 4 (2023)
Background Viral myocarditis is characterized by leukocyte infiltration of the heart and cardiomyocyte death. We recently identified C‐C chemokine ligand (CCL) 17 as a proinflammatory effector of C‐C chemokine receptor 2–positive macrophages an
Externí odkaz:
https://doaj.org/article/bbce09f4252d44e9942bdbfa999e5092
Autor:
Faliang Wang, Cuige Zhu, Shirong Cai, Aaron Boudreau, Sun-Joong Kim, Mina Bissell, Jieya Shao
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The essential actin-binding factor profilin-1 (Pfn1) is a non-classical tumor suppressor with the abilities toboth inhibit cellular proliferation and augment chemotherapy-induced apoptosis. Besides actin, Pfn1 interacts with proteins harboring the po
Externí odkaz:
https://doaj.org/article/426870026e304906be423ad064d99cbe
Autor:
Wenjing Qin, Abigail Godec, Xiaochun Zhang, Cuige Zhu, Jieya Shao, Yu Tao, Xianzhang Bu, Angela C. Hirbe
Publikováno v:
Cancer Medicine, Vol 8, Iss 11, Pp 5232-5241 (2019)
Abstract Background Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that arise most commonly in the setting of the Neurofibromatosis Type 1 (NF1) cancer predisposition syndrome. Despite aggressive multimodality therapy, outc
Externí odkaz:
https://doaj.org/article/54262ee0b13646428f1a44813ddd57a2
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
The essential actin-binding factor profilin-1 (Pfn1) is a non-classical tumor suppressor with the abilities toboth inhibit cellular proliferation and augment chemotherapy-induced apoptosis. Besides actin, Pfn1 interacts with proteins harboring the po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759e027a5cb396c588da3458ca446f5b
https://doi.org/10.3389/fcell.2021.692269
https://doi.org/10.3389/fcell.2021.692269
Autor:
Yu Tao, Abigail Godec, Angela C. Hirbe, Jieya Shao, Xianzhang Bu, Cuige Zhu, Xiaochun Zhang, Wenjing Qin
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 8, Iss 11, Pp 5232-5241 (2019)
Cancer Medicine, Vol 8, Iss 11, Pp 5232-5241 (2019)
Background Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that arise most commonly in the setting of the Neurofibromatosis Type 1 (NF1) cancer predisposition syndrome. Despite aggressive multimodality therapy, outcomes are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a94c5965e2a77961cd0b34eebe3bb1
http://europepmc.org/articles/PMC6718590
http://europepmc.org/articles/PMC6718590
Autor:
Jian Zhu, Samuel Leung, Karama Asleh, Jieya Shao, Cuige Zhu, Shan Li, Jennifer R. Won, Zhongsheng You, Anna Rogers, Torsten O. Nielsen, Jason M. Held, Kiran Vij, Dongxia Gao
Publikováno v:
Cell Reports
Spatiotemporal protein reorganization at DNA damage sites induced by genotoxic chemotherapies is crucial for DNA damage response (DDR), which influences treatment response by directing cancer cell fate. This process is orchestrated by valosin-contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7d4b24207cb47135951d6fa6f15bb63
Autor:
Cuige, Zhu, Anna, Rogers, Karama, Asleh, Jennifer, Won, Dongxia, Gao, Samuel, Leung, Shan, Li, Kiran R, Vij, Jian, Zhu, Jason M, Held, Zhongsheng, You, Torsten O, Nielsen, Jieya, Shao
Publikováno v:
Cell Reports
Summary Spatiotemporal protein reorganization at DNA damage sites induced by genotoxic chemotherapies is crucial for DNA damage response (DDR), which influences treatment response by directing cancer cell fate. This process is orchestrated by valosin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c930e96bd3cb5a204f0693a9622ddd15
https://pubmed.ncbi.nlm.nih.gov/32521270
https://pubmed.ncbi.nlm.nih.gov/32521270
Autor:
Xin Yue, Baojian Li, Jun Du, Daoyuan Chen, Cuige Zhu, Binhua Zhou, Wenjing Qin, Ziyi Liu, Weichao Zheng, Yingnan Cao, Ruimin Wang, Youqiao Wang, Xianzhang Bu, Haixia Sun
Publikováno v:
Biomedicine & Pharmacotherapy. 96:551-562
Major limitations of chalcones as clinical anticancer agents are water insolubility and poor bioavailability, which may be improved by a classic phosphate prodrug strategy that targets non-specific alkaline phosphatase (ALP) for releasing the parent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd63774133f0549eb55cf402350670e5
https://doi.org/10.1016/j.biopha.2017.10.006
https://doi.org/10.1016/j.biopha.2017.10.006
Autor:
Zhanfang Guo, Jason M. Held, Keren Wang, Sean Holohan, F. Wang, Jeremy Hoog, Cuige Zhu, Cynthia X. Ma, Sun-Joong Kim, Jieya Shao, Arshag D. Mooradian, Ziqian Li, Patrick L. Collins, Eugene M. Oltz
Publikováno v:
Cell reports
SUMMARY Aberrant expression of nuclear transporters and deregulated subcellular localization of their cargo proteins are emerging as drivers and therapeutic targets of cancer. Here, we present evidence that the nuclear exporter exportin-6 and its car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580be67704b2c444545b23cbad617ef4
http://europepmc.org/articles/PMC8006859
http://europepmc.org/articles/PMC8006859