Systemic administration of a novel Beclin 1-derived peptide significantly upregulates autophagy in the spinal motor neurons of autophagy reporter mice.

Autor: Amin A; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia., Perera ND; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia., Tomas D; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia., Cuic B; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia., Radwan M; Walter and Eliza Hall Institute of Medical Research, University of Melbourne, Parkville 3010, VIC, Australia., Hatters DM; Department of Biochemistry and Pharmacology and Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville 3010, VIC, Australia., Turner BJ; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia., Shabanpoor F; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia; School of Chemistry, University of Melbourne, VIC 3010, Australia. Electronic address: fazel.shabanpoor@unimelb.edu.au.

Publikováno v: International journal of pharmaceutics [Int J Pharm] 2024 Jun 25; Vol. 659, pp. 124198. Date of Electronic Publication: 2024 May 29.

Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis.

Autor: Wang T; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia., Tomas D; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia., Perera ND; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia., Cuic B; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia., Luikinga S; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia., Viden A; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia., Barton SK; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia., McLean CA; Department of Anatomical Pathology, Alfred Health, Melbourne, VIC, 3004, Australia., Samson AL; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3050, Australia., Southon A; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia., Bush AI; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia., Murphy JM; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC, 3050, Australia., Turner BJ; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, VIC, 3052, Australia. bradley.turner@florey.edu.au.; Perron Institute for Neurological and Translational Science, Queen Elizabeth Medical Centre, Nedlands, WA, Australia. bradley.turner@florey.edu.au.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2022 Jun; Vol. 29 (6), pp. 1187-1198. Date of Electronic Publication: 2021 Dec 02.

Endosomal escape cell-penetrating peptides significantly enhance pharmacological effectiveness and CNS activity of systemically administered antisense oligonucleotides.

Autor: Dastpeyman M; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia., Sharifi R; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia., Amin A; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia., Karas JA; School of Chemistry, The University of Melbourne, VIC 3010, Australia; The Bio21 Institute, University of Melbourne, 30 Flemington Rd., VIC 3010, Australia., Cuic B; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia., Pan Y; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Nicolazzo JA; Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville 3052, VIC, Australia., Turner BJ; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia; The Perron Institute for Neurological and Translational Science, Queen Elizabeth Medical Centre, Nedlands, Western Australia 6150, Australia., Shabanpoor F; The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville 3010, VIC, Australia. Electronic address: fazel.shabanpoor@unimelb.edu.au.

Publikováno v: International journal of pharmaceutics [Int J Pharm] 2021 Apr 15; Vol. 599, pp. 120398. Date of Electronic Publication: 2021 Feb 26.

Exploring germline recombination in Nestin-Cre transgenic mice using floxed androgen receptor.

Autor: McLeod VM; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Cuic B; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Chiam MDF; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Lau CL; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia., Turner BJ; Florey Institute of Neuroscience and Mental Health, University of Melbourne, Parkville, Victoria, Australia.; Perron Institute for Neurological and Translational Science, Queen Elizabeth Medical Centre, Nedlands, Western Australia, Australia.

Publikováno v: Genesis (New York, N.Y. : 2000) [Genesis] 2020 Nov; Vol. 58 (10-11), pp. e23390. Date of Electronic Publication: 2020 Aug 03.

Photophysical Characterization and In Vitro Evaluation of α-Mangostin-Loaded HDL Mimetic Nano-Complex in LN-229 Glioblastoma Spheroid Model.

Autor: Kapic, Ammar¹ (AUTHOR) ammarkapic@my.unthsc.edu, Sabnis, Nirupama¹ (AUTHOR) akpedjedossou@my.unthsc.edu, Dossou, Akpedje S.¹ (AUTHOR) bruce.bunnell@unthsc.edu, Chavez, Jose² (AUTHOR), Ceresa, Luca² (AUTHOR), Gryczynski, Zygmunt² (AUTHOR), Fudala, Rafal¹ (AUTHOR), Dickerman, Rob³ (AUTHOR), Bunnell, Bruce A.¹ (AUTHOR), Lacko, Andras G.¹ (AUTHOR) nirupama.sabnis@unthsc.edu

Publikováno v: International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 13, p7378. 23p.