Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Cuibai Wei"'
Autor:
Jin Gong, Shaoqi Li, Wenxian Sun, Pin Wang, Xiaodong Han, Chang Xu, Yufei Chen, Yuting Yang, Heya Luan, Ruina Li, Boye Wen, Sirong Lv, Runqi Chen, Jinxuan Guo, Cuibai Wei
Publikováno v:
Stem Cell Research, Vol 79, Iss , Pp 103501- (2024)
Apolipoprotein E (APOE)is the gene with greatest genetic risk for Alzheimer’s disease (AD). We successfully established a human induced pluripotent stem cell(iPSC) line from a woman mutated by APOE gene. The cell line was isolated from this woman
Externí odkaz:
https://doaj.org/article/496cd6551a284ddeab9b39cc0f5cdc6f
Autor:
Pin Wang, Chang Xu, Yufei Chen, Yuting Yang, Jin Gong, Wenxian Sun, Xiaodong Han, Heya Luan, Shaoqi Li, Ruina Li, Boye Wen, Sirong Lv, Cuibai Wei
Publikováno v:
BMJ Open, Vol 14, Iss 7 (2024)
Introduction The efficacy of multitarget neuroprotective drug DL-3-n-butylphthalide (NBP) in improving cognitive function has been confirmed in patients with vascular cognitive impairment without dementia. However, its efficacy in patients with sympt
Externí odkaz:
https://doaj.org/article/4258eb00a6334e37950a94c2d498175f
Autor:
Wenxian Sun, Jin Gong, Shaoqi Li, Pin Wang, Xiaodong Han, Chang Xu, Heya Luan, Ruina Li, Boye Wen, Cuibai Wei
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundAlzheimer’s disease (AD) is the predominant cause of dementia on a global scale, significantly impacting the health of the elderly population. The pathogenesis of AD is closely linked to neuroinflammation. The present study employs a bibl
Externí odkaz:
https://doaj.org/article/225f521135ac47c08cc31e2641cb58f1
Autor:
Pin Wang, Wenxian Sun, Jin Gong, Xiaodong Han, Chang Xu, Yufei Chen, Yuting Yang, Heya Luan, Shaoqi Li, Ruina Li, Boye Wen, Sirong Lv, Runqi Chen, Jinxuan Guo, Cuibai Wei
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103398- (2024)
Genetic polymorphism of apolipoprotein E (APOE) confers differential susceptibility to Alzheimer's disease (AD), and APOE ɛ4 variants is the most powerful risk factor for this disease. Here, we report the generation of a human induced pluripotent st
Externí odkaz:
https://doaj.org/article/f9359eb19b294472a491eac090dd1089
Autor:
Wenxian Sun, Pin Wang, Jin Gong, Yufei Chen, Yuting Yang, Heya Luan, Shaoqi Li, Ruina Li, Cuibai Wei
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103149- (2023)
The β-amyloid precursor protein (APP) is a crucial pathogenic gene linked to Alzheimer's disease (AD). A human induced pluripotent stem cell (iPSC) line was generated from peripheral blood mononuclear cells (PBMCs) isolated from a female with APP ge
Externí odkaz:
https://doaj.org/article/e93bbc208bee40829733fd4165e60ee5
Autor:
Huimin Cai, Yana Pang, Qi Wang, Wei Qin, Cuibai Wei, Ying Li, Tingting Li, Fangyu Li, Qigeng Wang, Yan Li, Yiping Wei, Longfei Jia
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background Neuronal- and astrocyte-derived exosomes have been identified as an optimal source for screening biomarkers for Alzheimer’s disease (AD). However, few studies focus on the bulk exosome population isolated from plasma of AD. This
Externí odkaz:
https://doaj.org/article/165c036d5935428787fe0c9d088d2f86
Autor:
Jianping Jia, Tingting Li, Jianwei Yang, Baian Chen, Wei Qin, Cuibai Wei, Yang Song, Qigeng Wang, Yan Li, Longfei Jia
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-8 (2022)
Abstract Objective To evaluate the diagnostic value of plasma β-amyloid (Aβ) seeding activity measured using a newly developed instrument to distinguish Alzheimer’s disease (AD) from other forms of dementia. Methods Seventy-nine AD patients, 64 n
Externí odkaz:
https://doaj.org/article/f83629debe0b49429ab49b5607eceee3
Autor:
Yan Li, Yuchen Qiao, Fen Wang, Cuibai Wei, Rui Wang, Hongmei Jin, Bingxin Xie, Jing You, Jianping Jia, Aihong Zhou
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundThe Chinese version of Boston Naming Test (BNT-C) is administered in China widely. However, the neuropsychological parameter of BNT-C in native Chinese-speaking elders in mainland China has not been explored systematically. The aim of this
Externí odkaz:
https://doaj.org/article/0cf7d149e28b4897aad726cb371f0027
Autor:
Huixuan Ma, Xinliang Lu, Aihong Zhou, Fen Wang, Xiumei Zuo, Minmin Zhan, Qi Zou, Shuting Gong, Yufei Chen, Jihui Lyu, Longfei Jia, Jianping Jia, Cuibai Wei
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundHigh-quality clinical practice guidelines (CPGs) are important for the effective treatment of behavioral and psychological symptoms of dementia (BPSD). However, recommendations provided by different quality guidelines may lead to varied cli
Externí odkaz:
https://doaj.org/article/7d234bd2975c4df886618edbf7b21e9e
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102690- (2022)
Mutations in the APP gene are popularly known as the second cause trigger the familial Alzheimer's disease (AD). We generated a human induced pluripotent stem cell (iPSC) line from the peripheral blood mononuclear cells isolated from an AD patient us
Externí odkaz:
https://doaj.org/article/2b42173bf1014e6a8f4e901135f8bdfa