Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Cui-Zan Cai"'
Autor:
Véronik Lachance, Qian Wang, Eric Sweet, Insup Choi, Cui-Zan Cai, Xu-Xu Zhuang, Yuanxi Zhang, Jessica Li Jiang, Robert D. Blitzer, Ozlem Bozdagi-Gunal, Bin Zhang, Jia-Hong Lu, Zhenyu Yue
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-13 (2019)
Abstract Background Dysfunctional autophagy is implicated in Alzheimer’s Disease (AD) pathogenesis. The alterations in the expression of many autophagy related genes (ATGs) have been reported in AD brains; however, the disparity of the changes conf
Externí odkaz:
https://doaj.org/article/08130cf12c0d4ff3966594d207ddd573
Autor:
Ming-Yue Wu, Cui-Zan Cai, Chuanbin Yang, Zhenyu Yue, Ye Chen, Zhao-Xiang Bian, Min Li, Jia-Hong Lu
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 2, Pp 323-324 (2022)
Externí odkaz:
https://doaj.org/article/827065d8017d4990b52848940da1ddc5
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-10 (2019)
Abstract Background Berberine is an isoquinoline alkaloid extracted from various Berberis species which is widely used in East Asia for a wide range of symptoms. Recently, neuroprotective effects of berberine in Alzheimer’s disease (AD) animal mode
Externí odkaz:
https://doaj.org/article/f86ae39e820a4d94a06a7a147e856314
Autor:
Sheng-Fang Wang, Liang-Feng Liu, Ming-Yue Wu, Cui-Zan Cai, Huanxing Su, Jieqiong Tan, Jia-Hong Lu, Min Li
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract 6-OHDA plus ascorbic acid (AA) has long been used to induce Parkinson’s disease in rodents, while only 6-OHDA is commonly used to induce cell damage in cellular PD models. AA was believed to act as an anti-oxidant to prevent the degradatio
Externí odkaz:
https://doaj.org/article/43af75dc2e204c9ca4ab9c1fd1ec99ca
Autor:
Ning-Ning Yuan, Cui-Zan Cai, Ming-Yue Wu, Qi Zhu, HuanXing Su, Min Li, JiaoYan Ren, Jie-Qiong Tan, Jia-Hong Lu
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterized by the accumulation of protein aggregates (namely Lewy bodies) in dopaminergic neurons in the substantia nigra region of the brain. Alpha-synuclein (α-syn)
Externí odkaz:
https://doaj.org/article/1bd14756cc3c4bef8c51cd2a28b8bb2d
Autor:
Cui-Zan Cai, Xu-Xu Zhuang, Qi Zhu, Ming-Yue Wu, Huanxing Su, Xiao-jin Wang, Ashok Iyaswamy, Zhenyu Yue, Qian Wang, Bin Zhang, Yu Xue, Jieqiong Tan, Min Li, Huanhuan He, Jia-Hong Lu
Publikováno v:
Theranostics. 12:1738-1755
Autor:
Chenglong Xie, Xu-Xu Zhuang, Zhangming Niu, Ruixue Ai, Sofie Lautrup, Shuangjia Zheng, Yinghui Jiang, Ruiyu Han, Tanima Sen Gupta, Shuqin Cao, Maria Jose Lagartos-Donate, Cui-Zan Cai, Li-Ming Xie, Domenica Caponio, Wen-Wen Wang, Tomas Schmauck-Medina, Jianying Zhang, He-ling Wang, Guofeng Lou, Xianglu Xiao, Wenhua Zheng, Konstantinos Palikaras, Guang Yang, Kim A. Caldwell, Guy A. Caldwell, Han-Ming Shen, Hilde Nilsen, Jia-Hong Lu, Evandro F. Fang
Publikováno v:
Nature Biomedical Engineering
A reduced removal of dysfunctional mitochondria is common to aging and age-related neurodegenerative pathologies such as Alzheimer’s disease (AD). Strategies for treating such impaired mitophagy would benefit from the identification of mitophagy mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3e5a9e23b0232005bb6ac90bd68d51e
http://hdl.handle.net/10852/99931
http://hdl.handle.net/10852/99931
Autor:
Min Li, Xu-Xu Zhuang, Ju-Xian Song, Zhou Zhu, Yuan Tan, Zhijian Huang, Jieqiong Tan, Jia-Hong Lu, Cui-Zan Cai, Huanxing Su, Zi-Ying Wang, Sheng-Fang Wang, Ming-Yue Wu
Publikováno v:
Cell Death and Disease, Vol 11, Iss 2, Pp 1-18 (2020)
Cell Death & Disease
Cell Death & Disease
Autophagy, a conserved cellular degradation and recycling process, can be enhanced by nutrient depletion, oxidative stress or other harmful conditions to maintain cell survival. 6-Hydroxydopamine/ascorbic acid (6-OHDA/AA) is commonly used to induce e
Autor:
Ye Chen, Zhaoxiang Bian, Min Li, Chuanbin Yang, Zhenyu Yue, Cui-Zan Cai, Jia-Hong Lu, Ming-Yue Wu
Publikováno v:
Neural Regeneration Research
Neural Regeneration Research, Vol 17, Iss 2, Pp 323-324 (2022)
Neural Regeneration Research, Vol 17, Iss 2, Pp 323-324 (2022)
Publikováno v:
Phytomedicine. 101:154125
Parkinson's disease (PD) is a multi-factorial neurodegenerative disease affecting motor function of patients. The hall markers of PD are dopaminergic neuron loss in the midbrain and the presence of intra-neuronal inclusion bodies mainly composed of a