Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Cui-Min Hu"'
Autor:
Liang Wang, Jian-Ping Deng, Jia-Jiu Yao, Hai-Rong Li, Gan Li, Cui-Min Hu, Zhong-Ze Fang, Jun Yuan, Yan-Yang Tu, Yong-Sheng Zhang
Publikováno v:
Molecules, Vol 17, Iss 5, Pp 4896-4903 (2012)
Gossypol, the polyphenolic constituent isolated from cottonseeds, has been used as a male antifertility drug for a long time, and has been demonstrated to exhibit excellent anti-tumor activity towards multiple cancer types. The toxic effects of gossy
Externí odkaz:
https://doaj.org/article/d6c7bd616cf348cd8035f1cc52128509
Autor:
Zuo Du, Kun Yang, Hong-Zhi Sun, Frank J. Gonzalez, Cui-Min Hu, Zhong-Ze Fang, Peipei Dong, Yun-Feng Cao, Yong-Zhe Liu, Zhi-Wei Fu, Zhi-Tu Zhu
Publikováno v:
Chemosphere. 185:983-990
Phthalate esters (PAEs) have been extensively used in industry as plasticizers and there remains concerns about their safety. The present study aimed to determine the inhibition of phthalate esters (PAEs) on the activity of the phase II drug-metaboli
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 49(11)
1.
Autor:
Zhi-Wei Fu, Zuo Du, Zhong-Ze Fang, Chun-Ting Huang, Kun Yang, Sai-Nan Li, Yong-Zhe Liu, Cui-Min Hu, Yun-Feng Cao, Xiao-Yu Sun
Publikováno v:
Chemosphere. 197
Phthalate monoesters are important metabolites of phthalate esters (PAEs) which have been extensively utilized in industry. This study aims to investigate the inhibition of phthalate monoesters on the activity of various isoforms of UDP-glucuronosylt
Autor:
Cui-Min Hu, Rong-Shan Li, Qian Zhang, Rui-Xue Ran, Peipei Dong, Yun-Feng Cao, Xue Wu, Yan-Yan Zhang, Wei-Ming Wang
Publikováno v:
Phytotherapy Research. 30:25-30
Drug-metabolizing enzymes inhibition-based drug–drug interaction remains to be the key limiting factor for the research and development of efficient herbal components to become clinical drugs. The present study aims to determine the inhibition of u
Autor:
Zhong-Ze Fang, Lingyun Hu, Yan-Yan Zhang, Zhuhua Yao, Ai-Lun Ma, Shu-Fen Wang, Kun Yang, Jun Deng, Haina Wang, Yong-Zhe Liu, Dan Lu, Cui-Min Hu
Publikováno v:
Chirality. 27:936-943
Rivaroxaban is an oral direct factor Xa (FXa) inhibitor clinically used to prevent and treat thromboembolic disorders. Drug-drug interaction (DDI) exist for rivaroxaban and the inhibitors of CYP3A4/5. This study aims to investigate the inhibition of
Autor:
Xin Liu, Cui-Min Hu, Lin Jia, Yun-Feng Cao, Wei Li, Yan-Yan Zhang, Yongzhe Liu, Li-Xuan Wang, Haina Wang, Zhong-Ze Fang
Publikováno v:
Chirality. 27:359-363
Zaltoprofen (ZLT) is a nonsteroidal antiinflammation drug, and has been clinically employed to treat rheumatoid arthritis, osteoarthritis, and other chronic inflammatory pain conditions. The present study aims to investigate the chirality influence o
Autor:
Zhi-Tu Zhu, Kun Yang, Zhong-Ze Fang, Yong-Zhe Liu, Zuo Du, Yun-Feng Cao, Hong-Zhi Sun, Guang Wang, Chun-Ze Zhang, Wei-Hua Zhang, Mo Hong, Cui-Min Hu, Xiao-Yu Sun
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 48(5)
1. Everolimus is an inhibitor of mammalian target of rapamycin (mTOR) and has been clinically utilized to prevent the rejection of organ transplants. This study aims to determine the inhibition of everolimus on the activity of phase-II drug-metaboliz
Autor:
Xiao-Yu Sun, Zhong-Ze Fang, Chun-Zhi Ai, Dong-Xue Sun, Yan-Qing Qu, Frank J. Gonzalez, Cui-Min Hu, Mo Hong, Xiaochi Ma, Peipei Dong, Changtao Jiang, Naoki Tanaka, Hai-Ying Ma, Yun-Feng Cao
Publikováno v:
Toxicology and Applied Pharmacology. 277:86-94
Herb–drug interaction strongly limits the clinical application of herbs and drugs, and the inhibition of herbal components towards important drug-metabolizing enzymes (DMEs) has been regarded as one of the most important reasons. The present study
Publikováno v:
Phytotherapy Research. 28:382-386
Scutellarin is an important bioactive flavonoid extracted from Erigeron breviscapus (Vant.) Hand-Mazz, and scutellarein is the corresponding aglycone of scutellarin. The present study aims to compare the inhibition potential of scutellarin and scutel