Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cui-Jiao Wen"'
Autor:
Ke-wei Zheng, Jia-Yuan Gong, Juan-Nan Chen, Yong Zhao, Yu-hua Hao, Cui-Jiao Wen, Zheng Tan, Yi-de He, Jia-yu Zhang
Publikováno v:
Nucleic Acids Research
G-quadruplex (G4) structures formed by guanine-rich nucleic acids are implicated in essential physiological and pathological processes and serve as important drug targets. The genome-wide detection of G4s in living cells is important for exploring th
Publikováno v:
Chemical Communications. 56:6567-6570
A dual-functional peptide-PNA (peptide nucleic acid) conjugate consisting of a PNA G3-tract and an RHAU23 peptide is devised to target nucleic acids bearing three tandem guanine tracts (G-tracts). The PNA G3-tract joins the three G-tracts to form a s
Autor:
Juan-Nan Chen, Cui-Jiao Wen, Ming-Liang Tang, Jia-Yuan Gong, Zheng Tan, Rui-Fang Duan, Yu-hua Hao, Yi-de He, Jia-yu Zhang, Ke-wei Zheng, Su-Ping Ren, Qun Yu
Publikováno v:
Proc Natl Acad Sci U S A
G-quadruplexes (G4s) formed by guanine-rich nucleic acids play a role in essential biological processes such as transcription and replication. Besides the >1.5 million putative G-4–forming sequences (PQSs), the human genome features >640 million si
Autor:
Xin-min Li, Zheng Tan, Yu-hua Hao, Yi-de He, Ke-wei Zheng, Jia-Yuan Gong, Yong Zhao, Cui-Jiao Wen
Publikováno v:
Journal of the American Chemical Society. 142(26)
Stabilization of G-quadruplexes (G4s) formed in guanine-rich (G-rich) nucleic acids by small-molecule ligands has been extensively explored as a therapeutic approach for diseases such as cancer. Finding ligands with sufficient affinity and specificit
Autor:
Juan-Nan Chen, Jia-Yuan Gong, Ke-wei Zheng, Jia-yu Zhang, Zheng Tan, Cui-Jiao Wen, Yi-de He, Yu-hua Hao
G-quadruplex (G4) structures formed by guanine-rich nucleic acids are implicated in essential physiological processes and serve as important drug targets. The genome-wide detection of G4s in living cells is important for exploring the biological role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0848c168678bb6b3f341f95dc81f08
https://doi.org/10.1101/2020.05.06.080622
https://doi.org/10.1101/2020.05.06.080622
Publikováno v:
Nucleic Acids Research
DNA supercoiling is an important regulator of gene activity. The transmission of transcription-generated supercoiling wave along a DNA helix provides a way for a gene being transcribed to communicate with and regulate its neighboring genes. Currently
Autor:
Jia-yuan Gong, Cui-jiao Wen, Ming-liang Tang, Rui-fang Duan, Juan-nan Chen, Jia-yu Zhang, Ke-wei Zheng, Yi-de He, Yu-hua Hao, Qun Yu, Su-ping Ren, Zheng Tan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/25/2021, Vol. 118 Issue 21, p1-9, 9p