Výsledky vyhledávání - "Cui Ying, Peng"

Akademický článek

Association between fat mass and obesity associated (FTO) gene rs9939609 A/T polymorphism and polycystic ovary syndrome: a systematic review and meta-analysis

Autor: Ai Ling Liu, Hui Jun Xie, Hong Yan Xie, Jun Liu, Jie Yin, Jin Song Hu, Cui Ying Peng

Publikováno v: BMC Medical Genetics, Vol 18, Iss 1, Pp 1-7 (2017)

Abstract Background Up to now, numerous case-control studies have reported the associations between fat mass and obesity associated (FTO) gene rs9939609 A/T polymorphism and polycystic ovary syndrome (PCOS), however, without a consistent result. Henc

Externí odkaz: https://doaj.org/article/7b45c4dfdc044806b56a3901fe1e5747

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The role of FTO variants in the susceptibility of polycystic ovary syndrome and in vitro fertilization outcomes in Chinese women

Autor: Yun Hua Zhu, Jing Zhou, Yu Lin Nie, Zi Fen Guo, Cui Lan Zhou, Ai Ling Liu, Cui Ying Peng, Zhi Liang Li, Hong Qing Liao, Dong Xiu He

Publikováno v: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. 34(8)

We investigated the association between single nucleotide polymorphisms (SNPs) in the fat mass and obesity associated (FTO) gene (rs9926289 A/G, rs79206939 A/G, rs9930506 A/G, rs8050136 A/C, and rs1588413 C/T) and polycystic ovary syndrome (PCOS), as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b644da6959f013bb57e8ec142f45695
https://pubmed.ncbi.nlm.nih.gov/29463151

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New Insights into mTOR Signal Pathways in Ovarian-Related Diseases: Polycystic Ovary Syndrome and Ovarian Cancer

Autor: Ai Ling, Liu, Hong Qing, Liao, Zhi Liang, Li, Jun, Liu, Cui Lan, Zhou, Zi Fen, Guo, Hong Yan, Xie, Cui Ying, Peng

Publikováno v: Asian Pacific Journal of Cancer Prevention : APJCP

mTOR, the mammalian target of rapamycin, is a conserved serine/threonine kinase which belongs to the phosphatidyl-linositol kinase-related kinase (PIKK) family. It has two complexes called mTORC1 and mTORC2. It is well established that mTOR plays imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b6e2479ea37f91ce6f3997cef0418eea
https://pubmed.ncbi.nlm.nih.gov/28122439

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The association between androgen receptor gene CAG polymorphism and polycystic ovary syndrome: a case-control study and meta-analysis

Autor: Yu Lin Nie, Hui Jun Xie, Jun Chen, Jie Yin, Zi Fen Guo, Jun Mei Zhou, Cui Ying Peng

Publikováno v: Journal of Assisted Reproduction and Genetics. 31:1211-1219

Many studies have been carried out to confirm the relationship between androgen receptor gene CAG repeat polymorphism and polycystic ovary syndrome (PCOS), without consistent results. Hence we conducted the current study to research this relationship

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938c26e0fac9518c53b2fe93a1f08ea8
https://doi.org/10.1007/s10815-014-0286-0

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[OATP 1B1 T521C/A388G is an important polymorphism gene related to neonatal hyperbilirubinemia]

Autor: Hai-xia, Zhang, Xin, Zhao, Zhi, Yang, Cui-ying, Peng, Rong, Long, Gui-nan, Li, Jun, Li, Zhou-kang, He

Publikováno v: Zhonghua er ke za zhi = Chinese journal of pediatrics. 48(9)

Multiple genetic and environmental factors contribute to the onset of many human diseases, such as neonatal hyperbilirubinemia. OATP 1B1 is an important polymorphism gene which transmembrane transports unconjugated bilirubin(UCB). Genetic polymorphis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9d3ae2bf3b3c406722e55aefc462fe30
https://pubmed.ncbi.nlm.nih.gov/21092521

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[Novel mechanism of 3' exonuclease of polymerase in maintenance of DNA replication fidelity and its application in SNP assay]

Autor: Lin-Ling, Chen, Jia, Zhang, Cui-Ying, Peng, Duan-Fang, Liao, Hong-Jian, Li, Han-Lin, Gao, Kai, Li

Publikováno v: Yi chuan = Hereditas. 27(2)

Polymerase with 3' to 5'exonulcease plays an important role in the maintenance of in vivo DNA replication fidelity. In order to develop more reliable SNP assays, we revisit the underlying molecular mechanisms by which DNA polymerases with 3' exonucle

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f73b6964e5fbac23d8fc0b849a6dc41f
https://pubmed.ncbi.nlm.nih.gov/15843359

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Exo+ proofreading polymerases mediate genetic analysis and its application in biomedical studies

Autor: Duan-fang, Liao, Lin-ling, Chen, Cui-ying, Peng, Jia, Zhang, Kai, Li

Publikováno v: Acta pharmacologica Sinica. 26(3)

Polymerases with a proofreading function in their internal 3' to 5' exonuclease possess high fidelity for DNA replication both in vivo and in vitro. The obstacle facing Exo+ polymerases for single nucleotide polymorphism (SNP) detection could be bypa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a568a3b1aaac93709d5dba330d1b4e92
https://pubmed.ncbi.nlm.nih.gov/15715925

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[Effect of 3' exonuclease activity of polymerase on extension of phosphorothioate-modified primers]

Autor: Zi-fen, Guo, Lin-ling, Chen, Jia, Zhang, Cui-ying, Peng, Xiang-dong, Yang, Xu, Zhang, Shu-ya, He, Duan-fang, Liao, Kai, Li

Publikováno v: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. 20(4)

To determine whether 3'phosphorothioate-modified-2 terminal mismatched primers can turn off DNA polymerization mediated by Exo(+) polymerase.Two-directional primer extension was performed using polymerase with and without 3' exonuclease activity. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0cd1e7879faaea8624f2736d05bef143
https://pubmed.ncbi.nlm.nih.gov/12903045

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