Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Cui Gai Bai"'
Publikováno v:
Future Medicinal Chemistry. 14:623-645
Aim: To synthesize new analogues of ponatinib and evaluate anti-leukemia cells and cytotoxicity. Methodology & results: The inhibitory activity of compounds 13a and 13c against K562 and HL60 cells was comparable to that of ponatinib (IC50 = 0.74, 0.8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d1bbad18f7f802758fbcbdf736d6e7
https://doi.org/10.4155/fmc-2022-0038
https://doi.org/10.4155/fmc-2022-0038
Autor:
Xiu-Juan Zhao, Yi-Ran Zhang, Wen-Fei Bai, Tong-Yan Sun, Yu-Fen Yang, Tong-Xin Wang, Cui-Gai Bai
Publikováno v:
Inflammopharmacology. 30(5)
The efficacy of the sulforaphane derivative JY4 was evaluated in acute and chronic mouse models of ulcerative colitis induced by dextran sodium sulfate. Oral administration of JY4 led to significant improvements in symptoms, with recovery of body wei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7978311a8f9f5c8f1a3cef81de5471d0
https://pubmed.ncbi.nlm.nih.gov/35943671
https://pubmed.ncbi.nlm.nih.gov/35943671
Autor:
Jing-Jing, Yin, Qian, Tang, Jia-Li, Gu, Ya-Fang, Li, Hui-Er, Gao, Mei, He, Ming, Yang, Wen-Shan, Zhang, Hui, Xu, Chao-Qun, Wang, Ying-Hui, Li, Cui-Gai, Bai, Ying-Dai, Gao
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 29(4)
To investigate the cytotoxic effect and its mechanism of the micromolecule compound on the leukemia cells.The cytotoxic effects of 28 Nilotinib derivatives on K562, KA, KG, HA and 32D cell lines were detected by MTT assays, and the compound Nilo 22 w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5d86fee727c6499e0168e1ab3121694
https://pubmed.ncbi.nlm.nih.gov/34362482
https://pubmed.ncbi.nlm.nih.gov/34362482
Autor:
Ye-Hui Shi, Dong-Fang Dai, Jing Li, Yan-Wei Dong, Yin Jiang, Huan-Gong Li, Yuan Gao, Chuan-Ke Chong, Hui-Ying Li, Xiao-Qian Chu, Cheng Yang, Quan Zhang, Zhong-Sheng Tong, Cui-Gai Bai, Yue Chen
Publikováno v:
Molecules, Vol 21, Iss 4, p 514 (2016)
Recent studies have shown that sulforaphane (SFN) selectively inhibits the growth of ALDH+ breast cancer stem-like cells.Herein, a series of SFN analogues were synthesized and evaluated against breast cancer cell lines MCF-7 and SUM-159, and the leuk
Externí odkaz:
https://doaj.org/article/5c0fc2e80acc47ed821e970524da7672
Publikováno v:
Medicinal Chemistry Research. 27:2437-2445
A series of triazolo-lapatinib hybrids were synthesized via copper (II)-oxide nanoparticle (Cu2O-NP)-catalyzed azide-alkyne cycloaddition. The ability of these compounds to reduce the viability of breast cancer SKBR3 and SUM159 cells and stem cell-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ecec2cc87a0e8cf26f6e43ee6ee236f
https://doi.org/10.1007/s00044-018-2247-0
https://doi.org/10.1007/s00044-018-2247-0
Autor:
Wenshan Zhang, Yue Sun, Yinghui Li, Mei He, Yahui Ding, Cui-Gai Bai, Huier Gao, Jiali Gu, Yingdai Gao, Jingjing Yin, Yafang Li
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(7)
Drug resistance is a common obstacle in leukemia treatment and failing to eradicate leukemia stem cells is the main cause of leukemia relapse. Previous studies have demonstrated that telomerase activity is associated with deregulated self-renewal of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4200adb46061c2c22310c557a615690e
https://pubmed.ncbi.nlm.nih.gov/32433826
https://pubmed.ncbi.nlm.nih.gov/32433826
Autor:
Dong Fang Dai, Xiao Qian Chu, Quan Zhang, Yue Chen, Jing Li, Yuan Gao, Hui Ying Li, Ye Hui Shi, Huan Gong Li, Jiang Yin, Yan Wei Dong, Zhong Sheng Tong, Chuan Ke Chong, Cui Gai Bai, Cheng Yang
Publikováno v:
Molecules, Vol 21, Iss 4, p 514 (2016)
Molecules; Volume 21; Issue 4; Pages: 514
Molecules
Molecules; Volume 21; Issue 4; Pages: 514
Molecules
Recent studies have shown that sulforaphane (SFN) selectively inhibits the growth of ALDH⁺ breast cancer stem-like cells.Herein, a series of SFN analogues were synthesized and evaluated against breast cancer cell lines MCF-7 and SUM-159, and the le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6e0fc5071c6570a2c353c6e0c78371
https://doi.org/10.3390/molecules21040514
https://doi.org/10.3390/molecules21040514