Coherent motion of monolayer sheets under confinement and its pathological implications

Autor: Soumya, S. S., Gupta, Animesh, Cugno, Andrea, Deseri, Luca, Dayal, Kaushik, Das, Dibyendu, Sen, Shamik, Inamdar, Mandar M.

Publikováno v: PLoS Comput Biol. 2015 Dec 21, 11(12) e1004670

Coherent angular rotation of epithelial cells is thought to contribute to many vital physiological processes including tissue morphogenesis and glandular formation. However, factors regulating this motion, and the implications of this motion if pertu

Externí odkaz: http://arxiv.org/abs/1507.06481

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Dendritic Spine Geometry and Ultrastructure Dictate the Spatiotemporal Dynamics of Second Messengers

Autor: Rangamani, Padmini, Bell, Miriam, Cugno, Andrea, Ohadi, Donya, Bartol, Thomas M., Iyengar, Ravi, Sejnowski, Terrence J.

Publikováno v: In Biophysical Journal 15 February 2019 116(3) Supplement 1:304a-304a

Small-on-Large Fractional Derivative–Based Single-Cell Model Incorporating Cytoskeleton Prestretch

Autor: Luca Deseri, Massimiliano Fraldi, Angelo Rosario Carotenuto, Nicola M. Pugno, Andrea Cugno, A. Cutolo

Publikováno v: Journal of engineering mechanics 143 (2017). doi:10.1061/(ASCE)EM.1943-7889.0001178
info:cnr-pdr/source/autori:Fraldi M.; Cugno A.; Carotenuto A.R.; Cutolo A.; Pugno N.M.; Deseri L./titolo:Small-on-large fractional derivative-based single-cell model incorporating cytoskeleton prestretch/doi:10.1061%2F(ASCE)EM.1943-7889.0001178/rivista:Journal of engineering mechanics/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:143

In recent years, experimental evidences have suggested important direct implications of viscoelasticity of human cells and cell cytoskeleton dynamics on some relevant collective and single-cell behaviors such as migration, adhesion, and morphogenesis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378fee1367fc446441e28e985457179b
https://doi.org/10.1061/(asce)em.1943-7889.0001178

A frequency-based hypothesis for mechanically targeting and selectively attacking cancer cells

Autor: Massimiliano Fraldi, Nicola M. Pugno, Luca Deseri, Andrea Cugno, Kaushik Dayal

Experimental studies recently performed on single cancer and healthy cells have demonstrated that the former are about 70% softer than the latter, regardless of the cell lines and the measurement technique used for determining the mechanical properti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d78b0d4f7e8f3f282d82fe2b7fd75d02
http://hdl.handle.net/11588/659004