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pro vyhledávání: '"Cuff AO"'
Tbet‐deficient mice have reduced NK cells in blood and spleen, but increased NK cells in bone marrow and lymph nodes, a phenotype that is thought to be due to defective migration. Here, we revisit the role of Tbet in NK cell bone marrow egress. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::0baf2a1a90a9b29dad2aef5686311033
http://hdl.handle.net/10044/1/79218
http://hdl.handle.net/10044/1/79218
Autor:
Male, Ronjon Chakraverty, Simone Dertschnig, Cuff Ao, Francesca Sillito, Andrew M. Hall, Tu Vinh Luong
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology, Vol 10 (2019)
The liver contains both NK cells and their less cytotoxic relatives, ILC1. Here, we investigate the role of NK cells and ILC1 in the obesity-associated condition, non-alcoholic fatty liver disease (NAFLD). In the livers of mice suffering from NAFLD,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ff7a3af3021c32bd33c9d563e48099
http://hdl.handle.net/10044/1/72989
http://hdl.handle.net/10044/1/72989
Mouse liver contains both Eomes-dependent conventional natural killer (cNK) cells and Tbet-dependent liver-resident type I innate lymphoid cells (ILC1). In order to better understand the role of ILC1, we attempted to generate mice that would lack liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::0544601e84773988f635e015764664d6
http://hdl.handle.net/10044/1/69899
http://hdl.handle.net/10044/1/69899
Human liver contains an Eomeshi population of NK cells that is not present in the blood. In this study, we show that these cells are characterized by a molecular signature that mediates their retention in the liver. By examining liver transplants whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::e8d2c4deef2fd7f30fc47d449259c888
http://hdl.handle.net/10044/1/69886
http://hdl.handle.net/10044/1/69886
Autor:
Henlon Y; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.; Centre for Early Life, University of Warwick, Coventry CV4 7AL, United Kingdom., Panir K; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.; Centre for Early Life, University of Warwick, Coventry CV4 7AL, United Kingdom., McIntyre I; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.; Centre for Early Life, University of Warwick, Coventry CV4 7AL, United Kingdom., Hogg C; Centre for Reproductive Health, Institute of Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, United Kingdom., Dhami P; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.; Centre for Early Life, University of Warwick, Coventry CV4 7AL, United Kingdom., Cuff AO; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.; Centre for Early Life, University of Warwick, Coventry CV4 7AL, United Kingdom., Senior A; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom., Moolchandani-Adwani N; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.; Centre for Early Life, University of Warwick, Coventry CV4 7AL, United Kingdom., Courtois ET; Single Cell Biology Lab, The Jackson Laboratory for Genomic Medicine, Farmington, CT 06032., Horne AW; Centre for Reproductive Health, Institute of Regeneration and Repair, The University of Edinburgh, Edinburgh EH16 4UU, United Kingdom., Rosser M; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.; Centre for Early Life, University of Warwick, Coventry CV4 7AL, United Kingdom., Ott S; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.; Centre for Early Life, University of Warwick, Coventry CV4 7AL, United Kingdom., Greaves E; Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, United Kingdom.; Centre for Early Life, University of Warwick, Coventry CV4 7AL, United Kingdom.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Sep 17; Vol. 121 (38), pp. e2405474121. Date of Electronic Publication: 2024 Sep 10.
Autor:
Forrest C; Institute of Immunity & Transplantation, UCL, London, NW3 2PP, UK., Chase TJG; Department of Surgery, UCL, Royal Free Campus, London, NW3 2PF, UK., Cuff AO; Department of Metabolism, Digestion and Reproduction, Imperial College London, Chelsea & Westminster Campus, London, SW10 9NH, UK., Maroulis D; Department of Surgery, UCL, Royal Free Campus, London, NW3 2PF, UK., Motallebzadeh R; Department of Surgery, UCL, Royal Free Campus, London, NW3 2PF, UK., Gander A; Department of Surgery, UCL, Royal Free Campus, London, NW3 2PF, UK., Davidson B; Department of Surgery, UCL, Royal Free Campus, London, NW3 2PF, UK., Griffiths P; Institute of Immunity & Transplantation, UCL, London, NW3 2PP, UK., Male V; Department of Metabolism, Digestion and Reproduction, Imperial College London, Chelsea & Westminster Campus, London, SW10 9NH, UK. v.male@imperial.ac.uk., Reeves M; Institute of Immunity & Transplantation, UCL, London, NW3 2PP, UK. matthew.reeves@ucl.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2023 Mar 14; Vol. 14 (1), pp. 1409. Date of Electronic Publication: 2023 Mar 14.
Autor:
Woon EV; Department of Metabolism, Digestion and Reproduction, Institute of Developmental Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.; The Fertility Centre, Chelsea and Westminster Hospital, London, United Kingdom., Nikolaou D; The Fertility Centre, Chelsea and Westminster Hospital, London, United Kingdom., MacLaran K; The Fertility Centre, Chelsea and Westminster Hospital, London, United Kingdom., Norman-Taylor J; The Fertility Centre, Chelsea and Westminster Hospital, London, United Kingdom., Bhagwat P; Department of Cellular Pathology, Imperial College Healthcare NHS Trust, Charing Cross Hospital, London, United Kingdom., Cuff AO; Department of Metabolism, Digestion and Reproduction, Institute of Developmental Reproductive and Developmental Biology, Imperial College London, London, United Kingdom., Johnson MR; Department of Metabolism, Digestion and Reproduction, Institute of Developmental Reproductive and Developmental Biology, Imperial College London, London, United Kingdom., Male V; Department of Metabolism, Digestion and Reproduction, Institute of Developmental Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.
Publikováno v:
Frontiers in immunology [Front Immunol] 2023 Jan 13; Vol. 13, pp. 1108163. Date of Electronic Publication: 2023 Jan 13 (Print Publication: 2022).
Autor:
Whettlock EM; Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom., Woon EV; Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom., Cuff AO; Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom., Browne B; Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom., Johnson MR; Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom., Male V; Department of Metabolism, Digestion and Reproduction, Institute of Reproductive and Developmental Biology, Imperial College London, London, United Kingdom.
Publikováno v:
Frontiers in immunology [Front Immunol] 2022 Jun 16; Vol. 13, pp. 880438. Date of Electronic Publication: 2022 Jun 16 (Print Publication: 2022).
Autor:
Cuff AO; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Perchet T; Unité Lymphopoïèse, Institut Pasteur, INSERM U1223, Université Paris Diderot, Paris, France., Dertschnig S; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; UCL Institute of Immunity and Transplantation, University College London, London, UK., Golub R; Unité Lymphopoïèse, Institut Pasteur, INSERM U1223, Université Paris Diderot, Paris, France., Male V; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
Publikováno v:
Immunology [Immunology] 2020 Sep; Vol. 161 (1), pp. 28-38. Date of Electronic Publication: 2020 Jun 08.
The Obese Liver Environment Mediates Conversion of NK Cells to a Less Cytotoxic ILC1-Like Phenotype.
Autor:
Cuff AO; Department of Surgery and Cancer, Imperial College London, London, United Kingdom., Sillito F; Institute of Immunity and Transplantation, University College London, London, United Kingdom., Dertschnig S; Institute of Immunity and Transplantation, University College London, London, United Kingdom., Hall A; Institute for Liver and Digestive Health, Royal Free Hospital and University College London, London, United Kingdom., Luong TV; Institute for Liver and Digestive Health, Royal Free Hospital and University College London, London, United Kingdom., Chakraverty R; Institute of Immunity and Transplantation, University College London, London, United Kingdom., Male V; Department of Surgery and Cancer, Imperial College London, London, United Kingdom.
Publikováno v:
Frontiers in immunology [Front Immunol] 2019 Sep 11; Vol. 10, pp. 2180. Date of Electronic Publication: 2019 Sep 11 (Print Publication: 2019).