Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Cuevas-Navarro A"'
Autor:
Castel, Pau, Dharmaiah, Srisathiyanarayanan, Sale, Matthew J., Messing, Simon, Rizzuto, Gabrielle, Cuevas-Navarro, Antonio, Cheng, Alice, Trnka, Michael J., Urisman, Anatoly, Esposito, Dominic, Simanshu, Dhirendra K., McCormick, Frank
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Aug . 118(33), 1-11.
Externí odkaz:
https://www.jstor.org/stable/27074813
Akademický článek
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Autor:
Cuevas-Navarro A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Pourfarjam Y; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hu F; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rodriguez DJ; Tri-Institutional MD-PhD Program, Weill Cornell Medical College and Rockefeller University and Memorial Sloan Kettering Cancer Center, New York, NY, USA., Vides A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Sang B; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fan S; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Goldgur Y; Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., de Stanchina E; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lito P; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. litop@mskcc.org.; Tri-Institutional MD-PhD Program, Weill Cornell Medical College and Rockefeller University and Memorial Sloan Kettering Cancer Center, New York, NY, USA. litop@mskcc.org.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. litop@mskcc.org.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. litop@mskcc.org.
Publikováno v:
Nature [Nature] 2024 Oct 30. Date of Electronic Publication: 2024 Oct 30.
Autor:
Antonio Cuevas-Navarro, Laura Rodriguez-Muñoz, Joaquim Grego-Bessa, Alice Cheng, Katherine A Rauen, Anatoly Urisman, Frank McCormick, Gerardo Jimenez, Pau Castel
Publikováno v:
eLife, Vol 11 (2022)
RAS GTPases are highly conserved proteins involved in the regulation of mitogenic signaling. We have previously described a novel Cullin 3 RING E3 ubiquitin ligase complex formed by the substrate adaptor protein LZTR1 that binds, ubiquitinates, and p
Externí odkaz:
https://doaj.org/article/186607128fba49338544764486aeac28
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Kim, Dongsung, Herdeis, Lorenz, Rudolph, Dorothea, Zhao, Yulei, Böttcher, Jark, Vides, Alberto, Ayala-Santos, Carlos I., Pourfarjam, Yasin, Cuevas-Navarro, Antonio, Xue, Jenny Y., Mantoulidis, Andreas, Bröker, Joachim, Wunberg, Tobias, Schaaf, Otmar, Popow, Johannes, Wolkerstorfer, Bernhard, Kropatsch, Katrin Gabriele, Qu, Rui, de Stanchina, Elisa, Sang, Ben
Publikováno v:
Nature; Jul2023, Vol. 619 Issue 7968, p160-166, 7p
Autor:
Dongsung Kim, Lorenz Herdeis, Dorothea Rudolph, Yulei Zhao, Jark Böttcher, Alberto Vides, Carlos I. Ayala-Santos, Yasin Pourfarjam, Antonio Cuevas-Navarro, Jenny Y. Xue, Andreas Mantoulidis, Joachim Bröker, Tobias Wunberg, Otmar Schaaf, Johannes Popow, Bernhard Wolkerstorfer, Katrin Gabriele Kropatsch, Rui Qu, Elisa de Stanchina, Ben Sang, Chuanchuan Li, Darryl B. McConnell, Norbert Kraut, Piro Lito
Publikováno v:
Nature.
KRAS is one of the most commonly mutated proteins in cancer, and efforts to directly inhibit its function have been continuing for decades. The most successful of these has been the development of covalent allele-specific inhibitors that trap KRAS G1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::409e1bd71739f2699717b05ba38036b5
https://doi.org/10.1038/s41586-023-06123-3
https://doi.org/10.1038/s41586-023-06123-3
Autor:
Omar Abdel-Wahab, Pau Castel, R. Coleman Lindsley, Frank McCormick, Neal Rosen, Justin Taylor, Sebastien Monette, Daichi Inoue, Michael F. Walsh, Elise Fiala, Tatiana S. Pavletich, Benjamin H. Durham, Steven Tittley, Dan Cui, Michael Singer, Caroline Erickson, Hana Cho, Robert F. Stanley, Won Jun Kim, Katherine Knorr, Salima Benbarche, Eric Wang, Simon J. Hogg, Bin Lu, Antonio Cuevas-Navarro, Rahul S. Vedula, Sisi Chen
Recently, screens for mediators of resistance to FLT3 and ABL kinase inhibitors in leukemia resulted in the discovery of LZTR1 as an adapter of a Cullin-3 RING E3 ubiquitin ligase complex responsible for the degradation of RAS GTPases. In parallel, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638f740c019d5ee713529476708607c2
https://doi.org/10.1158/2159-8290.c.6549783.v1
https://doi.org/10.1158/2159-8290.c.6549783.v1
Autor:
Omar Abdel-Wahab, Pau Castel, R. Coleman Lindsley, Frank McCormick, Neal Rosen, Justin Taylor, Sebastien Monette, Daichi Inoue, Michael F. Walsh, Elise Fiala, Tatiana S. Pavletich, Benjamin H. Durham, Steven Tittley, Dan Cui, Michael Singer, Caroline Erickson, Hana Cho, Robert F. Stanley, Won Jun Kim, Katherine Knorr, Salima Benbarche, Eric Wang, Simon J. Hogg, Bin Lu, Antonio Cuevas-Navarro, Rahul S. Vedula, Sisi Chen
Supplementary Figure from Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b02038ca94f1d0b396e493d0f80407
https://doi.org/10.1158/2159-8290.22542018
https://doi.org/10.1158/2159-8290.22542018