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Image processing approaches for microtubule remodeling quantification at the immunological synapse

Autor: Krentzel, Daniel, Gariboldi, Maria Isabella, Juzans, Marie, Mastrogiovanni, Marta, Mueller, Florian, Cuche, Céline, Di Bartolo, Vincenzo, Alcover, Andrés

Publikováno v: In Methods in Cell Biology

Chapter 1 - Imaging polarized granule release at the cytotoxic T cell immunological synapse using TIRF microscopy: Control by polarity regulators

Autor: Juzans, Marie, Cuche, Céline, Di Bartolo, Vincenzo, Alcover, Andrés

Publikováno v: The Immunological Synapse Part A
Clément Thomas; Lorenzo Galluzzi. The Immunological Synapse Part A, 173, Elsevier, pp.1-13, 2022, Methods in Cell Biology, 978-0-323-90154-3. ⟨10.1016/bs.mcb.2022.07.016⟩

International audience; Immunological synapse formation results from a profound T cell polarization process that involves the coordinated action of the actin and microtubule cytoskeleton, and the intracellular traffic of several vesicular organelles.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1a39d0642f2be564ee65f844972680f5
https://hal-pasteur.archives-ouvertes.fr/pasteur-03992601

Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function.

Autor: Navas, Victor H.^1,2,3, Cuche, Céline^1,2,4, Alcover, Andres^1,2,4, Di Bartolo, Vincenzo^1,2,4 vincenzo.di-bartolo@pasteur.fr

Publikováno v: PLoS ONE. 1/20/2017, Vol. 12 Issue 1, p1-17. 17p.

Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function

Autor: Navas, Victor H, Cuche, Céline, Alcover, Andres, Di Bartolo, Vincenzo

Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 1, p e0170396 (2017)
PLoS ONE, 2017, 12 (1), pp.e0170396. ⟨10.1371/journal.pone.0170396⟩
PLoS ONE, Public Library of Science, 2017, 12 (1), pp.e0170396. ⟨10.1371/journal.pone.0170396⟩

International audience; The adapter protein SLP76 is a key orchestrator of T cell receptor (TCR) signal transduction. We previously identified a negative feedback loop that modulates T cell activation, involving phosphorylation of Ser376 of SLP76 by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::149feb0499b077f182147d84dd2bc1af
https://pubmed.ncbi.nlm.nih.gov/28107427