Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction.

Autor: Siew K; London Tubular Centre, Department of Renal Medicine, University College London, London, UK. k.siew@ucl.ac.uk., Nestler KA; The Institute for Biomedical Sciences (IBS), The George Washington University, Washington, DC, USA., Nelson C; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA., D'Ambrosio V; London Tubular Centre, Department of Renal Medicine, University College London, London, UK.; Department of Experimental and Translational Medicine, Università Cattolica del Sacro Cuore di Roma, Rome, Italy., Zhong C; London Tubular Centre, Department of Renal Medicine, University College London, London, UK., Li Z; London Tubular Centre, Department of Renal Medicine, University College London, London, UK.; Centre for Advanced Biomedical Imaging, University College London, London, UK.; Centre for Computational Medicine, University College London, London, UK., Grillo A; London Tubular Centre, Department of Renal Medicine, University College London, London, UK., Wan ER; London Tubular Centre, Department of Renal Medicine, University College London, London, UK., Patel V; Department of Renal Medicine, University College London, London, UK., Overbey E; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY, USA., Kim J; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY, USA., Yun S; University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Vaughan MB; School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland.; Tissue Engineering and Biomaterials Group, Ghent University, Ghent, Belgium.; Center for Medical Genetics, Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Cheshire C; Bioinformatics and Computational Biology Laboratory, The Francis Crick Institute, London, UK., Cubitt L; Applied Biotechnology Laboratory, The Francis Crick Institute, London, UK., Broni-Tabi J; Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK., Al-Jaber MY; Anti-Doping Laboratory Qatar, Doha, Qatar., Boyko V; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Meydan C; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY, USA., Barker P; MRC MDU Mouse Biochemistry Laboratory, University of Cambridge, Cambridge, UK., Arif S; Center for Data Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Afsari F; Department of Medicine-Nephrology & Intelligent Critical Care Center, University of Florida, Gainesville, FL, USA., Allen N; Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA., Al-Maadheed M; Anti-Doping Laboratory Qatar, Doha, Qatar.; Centre of Metabolism and Inflammation, University College London, London, UK., Altinok S; School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Bah N; Applied Biotechnology Laboratory, The Francis Crick Institute, London, UK., Border S; Department of Medicine-Nephrology & Intelligent Critical Care Center, University of Florida, Gainesville, FL, USA., Brown AL; Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Burling K; MRC MDU Mouse Biochemistry Laboratory, University of Cambridge, Cambridge, UK., Cheng-Campbell M; Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.; Blue Marble Space Institute of Science, Seattle, WA, USA., Colón LM; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA., Degoricija L; KBR, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Figg N; Department of Medicine, University of Cambridge, Cambridge, UK., Finch R; School of Health, Science and Wellbeing, Staffordshire University, Stoke-on-Trent, UK., Foox J; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY, USA., Faridi P; Monash Proteomics and Metabolomics Platform, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., French A; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Gebre S; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Gordon P; Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK., Houerbi N; Physiology, Biophysics & Systems Biology, Weill Cornell Medical College, New York, NY, USA., Valipour Kahrood H; Monash Proteomics and Metabolomics Platform, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia.; Monash Bioinformatics Platform, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Kiffer FC; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Klosinska AS; Division of Experimental Medicine & Immunotherapeutics (EMIT), Department of Medicine, University of Cambridge, Cambridge, UK., Kubik A; Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA., Lee HC; Monash Proteomics and Metabolomics Platform, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Li Y; State Key Laboratory of Space Medicine Fundamentals and Application, China Astronaut Research and Training Center, Beijing, China., Lucarelli N; Department of Medicine-Nephrology & Intelligent Critical Care Center, University of Florida, Gainesville, FL, USA., Marullo AL; School of Medicine, College of Medicine and Health, University College Cork, Cork, Ireland., Matei I; Cornell Center for Immunology, Cornell University, Ithaca, NY, USA.; Children's Cancer and Blood Foundation Laboratories, Departments of Pediatrics and Cell and Developmental Biology, Drukier Institute for Children's Health, Meyer Cancer Center, Weill Cornell Medical College, New York, NY, USA., McCann CM; Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Mimar S; Department of Medicine-Nephrology & Intelligent Critical Care Center, University of Florida, Gainesville, FL, USA., Naglah A; Department of Medicine-Nephrology & Intelligent Critical Care Center, University of Florida, Gainesville, FL, USA., Nicod J; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., O'Shaughnessy KM; Division of Experimental Medicine & Immunotherapeutics (EMIT), Department of Medicine, University of Cambridge, Cambridge, UK., Oliveira LC; Blue Marble Space Institute of Science, Seattle, WA, USA.; Federal University of São Paulo (UNIFESP), São Paulo, Brazil., Oswalt L; Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Patras LI; Pediatrics, Weill Cornell Medical College, New York, NY, USA., Lai Polo SH; KBR, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Rodríguez-Lopez M; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Roufosse C; Department of Immunology and Inflammation, Imperial College London, London, UK., Sadeghi-Alavijeh O; Department of Renal Medicine, University College London, London, UK., Sanchez-Hodge R; Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Paul AS; Department of Medicine-Nephrology & Intelligent Critical Care Center, University of Florida, Gainesville, FL, USA., Schittenhelm RB; Monash Proteomics and Metabolomics Platform, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Schweickart A; Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY, USA.; Englander Institute for Precision Medicine, Weill Cornell Medical College, New York, NY, USA., Scott RT; KBR, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Choy Lim Kam Sian TC; Monash Proteomics and Metabolomics Platform, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., da Silveira WA; School of Health, Science and Wellbeing, Staffordshire University, Stoke-on-Trent, UK.; International Space University, 67400, Illkirch-Graffenstaden, France., Slawinski H; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Snell D; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Sosa J; University Health Network, Toronto, ON, Canada., Saravia-Butler AM; KBR, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Tabetah M; Department of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN, USA., Tanuwidjaya E; Monash Proteomics and Metabolomics Platform, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Walker-Samuel S; Centre for Advanced Biomedical Imaging, University College London, London, UK.; Centre for Computational Medicine, University College London, London, UK., Yang X; Proteomics, King's College London, London, UK., Yasmin; Division of Experimental Medicine & Immunotherapeutics (EMIT), Department of Medicine, University of Cambridge, Cambridge, UK., Zhang H; Monash Proteomics and Metabolomics Platform, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Godovac-Zimmermann J; Department of Renal Medicine, University College London, London, UK., Sarder P; Department of Medicine-Quantitative Health Section, University of Florida, Gainesville, FL, USA.; Departments of Biomedical Engineering and Electrical and Computer Engineering, University of Florida, Gainesville, FL, USA., Sanders LM; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA.; Blue Marble Space Institute of Science, Seattle, WA, USA., Costes SV; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Campbell RAA; Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK., Karouia F; Blue Marble Space Institute of Science, Seattle, WA, USA.; Space Research Within Reach, San Francisco, CA, USA.; Center for Space Medicine, Baylor College of Medicine, Houston, TX, USA., Mohamed-Alis V; Anti-Doping Laboratory Qatar, Doha, Qatar.; Centre of Metabolism and Inflammation, University College London, London, UK., Rodriques S; Applied Biotechnology Laboratory, The Francis Crick Institute, London, UK., Lynham S; Proteomics, King's College London, London, UK., Steele JR; Monash Proteomics and Metabolomics Platform, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia., Baranzini S; Weill Institute for Neurosciences, Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Fazelinia H; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia Research Institute, Philadelphia, PA, USA., Dai Z; State Key Laboratory of Space Medicine Fundamentals and Application, China Astronaut Research and Training Center, Beijing, China., Uruno A; Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan., Shiba D; Mouse Epigenetics Project, ISS/Kibo experiment, Japan Aerospace Exploration Agency (JAXA), Tsukuba, Ibaraki, Japan.; JEM Utilization Center, Human Spaceflight Technology Directorate, Japan Aerospace Exploration Agency (JAXA), Tsukuba, Ibaraki, Japan., Yamamoto M; Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan.; Department of Medical Biochemistry, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan., A C Almeida E; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Blaber E; Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.; Center for Biotechnology & Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, USA.; Stanley Center for Psychiatric Research, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA., Schisler JC; Pharmacology, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Eisch AJ; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Neuroscience, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Muratani M; Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan., Zwart SR; Department of Preventative Medicine and Community Health, University of Texas Medical Branch, Galveston, TX, USA., Smith SM; NASA Johnson Space Center, Houston, TX, USA., Galazka JM; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Mason CE; Department of Physiology and Biophysics, Weill Cornell Medical College, New York, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY, USA.; The WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medical College, New York, NY, USA.; The Feil Family Brain and Mind Research Institute, Weill Cornell Medical College, New York, NY, USA., Beheshti A; KBR, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA.; Broad Institute, Cambridge, MA, USA.; Space Biosciences Division, Universities Space Research Association (USRA), Washington, DC, USA., Walsh SB; London Tubular Centre, Department of Renal Medicine, University College London, London, UK. stephen.walsh@ucl.ac.uk.

Publikováno v: Nature communications [Nat Commun] 2024 Jun 11; Vol. 15 (1), pp. 4923. Date of Electronic Publication: 2024 Jun 11.

Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London.

Autor: Bailey C; Cancer Evolution and Genome Instability Laboratory, London NW1 1AT, UK; Francis Crick Institute, London NW1 1AT, UK; University College London Hospitals NHS Foundation Trust, London, UK; University College London, London, UK., Sanderson T; Malaria Biochemistry Laboratory, London NW1 1AT, UK; COVID-19 Genomics UK Consortium, Wellcome Trust Sanger Institute, Cambridge, UK., Townsley H; Francis Crick Institute, London NW1 1AT, UK; University College London Hospitals NHS Foundation Trust, London, UK., Goldman J; Scientific Computing STP, London NW1 1AT, UK., Black JRM; Cancer Evolution and Genome Instability Laboratory, London NW1 1AT, UK; University College London, London, UK., Young G; Applied Biotechnology Laboratory, London NW1 1AT, UK., Goldstone R; Advanced Sequencing Facility, London NW1 1AT, UK; Bioinformatics and Biostatistics STP, London NW1 1AT, UK., Fowler AS; Advanced Sequencing Facility, London NW1 1AT, UK., Ward S; Cancer Evolution and Genome Instability Laboratory, London NW1 1AT, UK; Advanced Sequencing Facility, London NW1 1AT, UK., Jackson DJ; Advanced Sequencing Facility, London NW1 1AT, UK., Cubitt L; Advanced Sequencing Facility, London NW1 1AT, UK., Dearing V; Advanced Sequencing Facility, London NW1 1AT, UK., O'Neil O; Advanced Sequencing Facility, London NW1 1AT, UK., Crawford M; Advanced Sequencing Facility, London NW1 1AT, UK., Snell D; Advanced Sequencing Facility, London NW1 1AT, UK., Finadis M; Advanced Sequencing Facility, London NW1 1AT, UK., Edwards A; Advanced Sequencing Facility, London NW1 1AT, UK., Perez-Lloret J; Advanced Sequencing Facility, London NW1 1AT, UK., Gahir J; Francis Crick Institute, London NW1 1AT, UK; University College London Hospitals NHS Foundation Trust, London, UK., Carr EJ; Cell Biology of Infection Laboratory, London NW1 1AT, UK; Francis Crick Institute, London NW1 1AT, UK., Riddell A; Flow Cytometry STP, London NW1 1AT, UK., Aitken J; Information Technology Office, London NW1 1AT, UK., Ambrose K; Scientific Computing STP, London NW1 1AT, UK., Sawyer C; Scientific Computing STP, London NW1 1AT, UK., O'Reilly N; Protein Chemistry STP, London NW1 1AT, UK., Caidan S; Francis Crick Institute, London NW1 1AT, UK., Wu MY; COVID Surveillance Unit, London NW1 1AT, UK., Walker PA; Structural Biology STP, London NW1 1AT, UK., Hindmarsh S; Scientific Computing STP, London NW1 1AT, UK., Howell M; Highthroughput Screening Laboratory, London NW1 1AT, UK., Jordan A; Information Technology Office, London NW1 1AT, UK., Fleming J; Information Technology Office, London NW1 1AT, UK., Houlihan C; University College London Hospitals NHS Foundation Trust, London, UK., Nastouli E; University College London Hospitals NHS Foundation Trust, London, UK., Moores R; Royal Free London NHS Foundation Trust, London, UK., Hsu D; Royal Free London NHS Foundation Trust, London, UK., Papineni P; London Northwest University Healthcare NHS Trust, London, UK., Corrah T; London Northwest University Healthcare NHS Trust, London, UK., Gilson R; Central and Northwest London NHS Foundation Trust, London, UK., MacRae J; Metabolomics STP, London NW1 1AT, UK., Hubank M; Royal Marsden Hospitals NHS Foundation Trust, London, UK., Van As N; Royal Marsden Hospitals NHS Foundation Trust, London, UK., Turajlic S; Cancer Dynamics Laboratory, London NW1 1AT, UK., Beale R; Cell Biology of Infection Laboratory, London NW1 1AT, UK; University College London, London, UK; Genotype to Phenotype Consortium UK, Imperial College London, London, UK., Levi M; University College London Hospitals NHS Foundation Trust, London, UK., Barrell S; Francis Crick Institute, London NW1 1AT, UK., Williams B; University College London Hospitals NHS Foundation Trust, London, UK; University College London, London, UK., Gamblin S; Francis Crick Institute, London NW1 1AT, UK., Nicod J; Advanced Sequencing Facility, London NW1 1AT, UK; Francis Crick Institute, London NW1 1AT, UK., Gandhi S; Neurodegeneration Laboratory, London NW1 1AT, UK; Francis Crick Institute, London NW1 1AT, UK; University College London, London, UK., Bauer DLV; RNA Virus Replication Laboratory, London NW1 1AT, UK; Genotype to Phenotype Consortium UK, Imperial College London, London, UK., Wall EC; Francis Crick Institute, London NW1 1AT, UK; University College London Hospitals NHS Foundation Trust, London, UK. Electronic address: emma.wall@crick.ac.uk., Swanton C; Cancer Evolution and Genome Instability Laboratory, London NW1 1AT, UK; Francis Crick Institute, London NW1 1AT, UK; University College London Hospitals NHS Foundation Trust, London, UK; University College London, London, UK.

Publikováno v: Lancet (London, England) [Lancet] 2023 Jul 01; Vol. 402 (10395), pp. 21-24. Date of Electronic Publication: 2023 Jun 19.

Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study.

Autor: Fendler A; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK., Au L; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Shepherd STC; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Byrne F; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK., Cerrone M; Tuberculosis Laboratory, The Francis Crick Institute, London, UK.; Department of Infectious Disease, Imperial College London, London, UK., Boos LA; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Rzeniewicz K; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK., Gordon W; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK., Shum B; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK.; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Gerard CL; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK., Ward B; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK., Xie W; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK., Schmitt AM; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Joharatnam-Hogan N; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Cornish GH; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK., Pule M; Department of Haematology, University College London Cancer Institute, London, UK.; Autolus Ltd., London, UK., Mekkaoui L; Autolus Ltd., London, UK., Ng KW; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK., Carlyle E; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Edmonds K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Rosario LD; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Sarker S; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Lingard K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Mangwende M; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Holt L; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Ahmod H; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Stone R; Experimental Histopathology Laboratory, The Francis Crick Institute, London, UK., Gomes C; Experimental Histopathology Laboratory, The Francis Crick Institute, London, UK., Flynn HR; Mass Spectrometry Proteomics Science Technology Platform, The Francis Crick Institute, London, UK., Agua-Doce A; Flow Cytometry Scientific Technology Platform, The Francis Crick Institute, London, UK., Hobson P; Flow Cytometry Scientific Technology Platform, The Francis Crick Institute, London, UK., Caidan S; Safety, Health and Sustainability, The Francis Crick Institute, London, UK., Howell M; High Throughput Screening Laboratory, The Francis Crick Institute, London, UK., Wu M; High Throughput Screening Laboratory, The Francis Crick Institute, London, UK., Goldstone R; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Crawford M; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Cubitt L; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Patel H; Department of Bioinformatics and Biostatistics, The Francis Crick Institute, London, UK., Gavrielides M; Scientific Computing Scientific Technology Platform, The Francis Crick Institute, London, UK., Nye E; Experimental Histopathology Laboratory, The Francis Crick Institute, London, UK., Snijders AP; Mass Spectrometry Proteomics Science Technology Platform, The Francis Crick Institute, London, UK., MacRae JI; Metabolomics Scientific Technology Platform, The Francis Crick Institute, London, UK., Nicod J; Advanced Sequencing Facility, The Francis Crick Institute, London, UK., Gronthoud F; Department of Pathology, The Royal Marsden NHS Foundation Trust, London, UK., Shea RL; Department of Pathology, The Royal Marsden NHS Foundation Trust, London, UK.; Translational Cancer Biochemistry Laboratory, The Institute of Cancer Research, London, UK., Messiou C; Department of Radiology, The Royal Marsden NHS Foundation Trust, London, UK., Cunningham D; Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey, London, UK., Chau I; Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey, London, UK., Starling N; Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey, London, UK., Turner N; Breast Unit, The Royal Marsden NHS Foundation Trust, London, UK.; Breast Cancer Now Toby Robins Breast Cancer Research Centre, The Institute of Cancer Research, London, UK., Welsh L; Neuro-oncology Unit, The Royal Marsden NHS Foundation Trust, London, UK., van As N; Clinical Oncology Unit, The Royal Marsden NHS Foundation Trust, London, UK., Jones RL; Sarcoma Unit, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK., Droney J; Palliative Medicine, The Royal Marsden NHS Foundation Trust, London, UK., Banerjee S; Gynaecology Unit, The Royal Marsden NHS Foundation Trust, London, UK., Tatham KC; Anaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London, UK.; Department of Surgery and Cancer, Imperial College London, London, UK., Jhanji S; Anaesthetics, Perioperative Medicine and Pain Department, The Royal Marsden NHS Foundation Trust, London, UK., O'Brien M; Lung Unit, The Royal Marsden NHS Foundation Trust, London, UK., Curtis O; Lung Unit, The Royal Marsden NHS Foundation Trust, London, UK., Harrington K; Head and Neck Unit, The Royal Marsden NHS Foundation Trust, London, UK.; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Bhide S; Head and Neck Unit, The Royal Marsden NHS Foundation Trust, London, UK.; Targeted Therapy Team, The Institute of Cancer Research, London, UK., Bazin J; Haemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London, UK., Robinson A; Haemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London, UK., Stephenson C; Haemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London, UK., Slattery T; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Khan Y; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Tippu Z; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Leslie I; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Gennatas S; Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London, UK.; Department of Medical Oncology, Guy's Hospital, London, UK., Okines A; Breast Unit, The Royal Marsden NHS Foundation Trust, London, UK.; Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London, UK., Reid A; Uro-oncology Unit, The Royal Marsden NHS Foundation Trust, Surrey, UK., Young K; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Furness AJS; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Pickering L; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Gandhi S; Neurodegeneration Biology Laboratory, The Francis Crick Institute, London, UK.; UCL Queen Square Institute of Neurology, London, UK., Gamblin S; Structural Biology of Disease Processes Laboratory, The Francis Crick Institute, London, UK., Swanton C; Cancer Evolution and Genome Instability Laboratory, The Francis Crick Institute, London, UK.; University College London Cancer Institute, London, UK., Nicholson E; Haemato-oncology Unit, The Royal Marsden NHS Foundation Trust, London, UK., Kumar S; Gastrointestinal Unit, The Royal Marsden NHS Foundation Trust, London and Surrey, London, UK., Yousaf N; Lung Unit, The Royal Marsden NHS Foundation Trust, London, UK.; Acute Oncology Service, The Royal Marsden NHS Foundation Trust, London, UK., Wilkinson KA; Tuberculosis Laboratory, The Francis Crick Institute, London, UK.; Wellcome Center for Infectious Disease Research in Africa, University Cape Town, Cape Town, Republic of South Africa., Swerdlow A; Division of Genetics and Epidemiology and Division of Breast Cancer Research, The Institute of Cancer Research, London, UK., Harvey R; Worldwide Influenza Centre, The Francis Crick Institute, London, UK., Kassiotis G; Retroviral Immunology Laboratory, The Francis Crick Institute, London, UK., Larkin J; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK., Wilkinson RJ; Tuberculosis Laboratory, The Francis Crick Institute, London, UK.; Department of Infectious Disease, Imperial College London, London, UK.; Wellcome Center for Infectious Disease Research in Africa, University Cape Town, Cape Town, Republic of South Africa., Turajlic S; Cancer Dynamics Laboratory, The Francis Crick Institute, London, UK. samra.turajlic@crick.ac.uk.; Skin and Renal Units, The Royal Marsden NHS Foundation Trust, London, UK. samra.turajlic@crick.ac.uk.

Publikováno v: Nature cancer [Nat Cancer] 2021 Dec; Vol. 2 (12), pp. 1321-1337. Date of Electronic Publication: 2021 Oct 27.

SARS-CoV-2 detection by a clinical diagnostic RT-LAMP assay.

Autor: Buck MD; The Francis Crick Institute, London, NW1 1AT, UK., Poirier EZ; The Francis Crick Institute, London, NW1 1AT, UK., Cardoso A; The Francis Crick Institute, London, NW1 1AT, UK., Frederico B; The Francis Crick Institute, London, NW1 1AT, UK., Canton J; The Francis Crick Institute, London, NW1 1AT, UK., Barrell S; The Francis Crick Institute, London, NW1 1AT, UK., Beale R; The Francis Crick Institute, London, NW1 1AT, UK., Byrne R; The Francis Crick Institute, London, NW1 1AT, UK., Caidan S; The Francis Crick Institute, London, NW1 1AT, UK., Crawford M; The Francis Crick Institute, London, NW1 1AT, UK., Cubitt L; The Francis Crick Institute, London, NW1 1AT, UK., Gandhi S; The Francis Crick Institute, London, NW1 1AT, UK.; University College London, London, WC1E 6BT, UK.; University College London Hospitals NHS Trust, London, NW1 2PG, UK., Goldstone R; The Francis Crick Institute, London, NW1 1AT, UK., Grant PR; Healh Service Laboratories, London, WC1H 9AX, UK., Gulati K; New England Biolabs, Ipswich, MA, USA., Hindmarsh S; The Francis Crick Institute, London, NW1 1AT, UK., Howell M; The Francis Crick Institute, London, NW1 1AT, UK., Hubank M; The Royal Marsden Hospital, Sutton, SM2 5NG, UK.; The Institute of Cancer Research, London, SW7 3RP, UK., Instrell R; The Francis Crick Institute, London, NW1 1AT, UK., Jiang M; The Francis Crick Institute, London, NW1 1AT, UK., Kassiotis G; The Francis Crick Institute, London, NW1 1AT, UK., Lu WT; The Francis Crick Institute, London, NW1 1AT, UK., MacRae JI; The Francis Crick Institute, London, NW1 1AT, UK., Martini I; The Royal Free Hospital, London, NW3 2QG, UK., Miller D; New England Biolabs, Ipswich, MA, USA., Moore D; University College London, London, WC1E 6BT, UK.; University College London Hospitals NHS Trust, London, NW1 2PG, UK., Nastouli E; The Francis Crick Institute, London, NW1 1AT, UK.; University College London Hospitals NHS Trust, London, NW1 2PG, UK.; University College London GOS Institute of Child Health, London, WC1N 1EH, UK., Nicod J; The Francis Crick Institute, London, NW1 1AT, UK., Nightingale L; The Francis Crick Institute, London, NW1 1AT, UK., Olsen J; The Francis Crick Institute, London, NW1 1AT, UK., Oomatia A; The Royal Free Hospital, London, NW3 2QG, UK., O'Reilly N; The Francis Crick Institute, London, NW1 1AT, UK., Rideg A; The Francis Crick Institute, London, NW1 1AT, UK., Song OR; The Francis Crick Institute, London, NW1 1AT, UK., Strange A; The Francis Crick Institute, London, NW1 1AT, UK., Swanton C; The Francis Crick Institute, London, NW1 1AT, UK.; University College London, London, WC1E 6BT, UK.; University College London Hospitals NHS Trust, London, NW1 2PG, UK., Turajlic S; The Francis Crick Institute, London, NW1 1AT, UK.; The Royal Marsden Hospital, Sutton, SM2 5NG, UK., Wu M; The Francis Crick Institute, London, NW1 1AT, UK., Reis e Sousa C; The Francis Crick Institute, London, NW1 1AT, UK.

Publikováno v: Wellcome open research [Wellcome Open Res] 2021 May 21; Vol. 6, pp. 9. Date of Electronic Publication: 2021 May 21 (Print Publication: 2021).

Scalable and robust SARS-CoV-2 testing in an academic center.

Autor: Aitken J; The Francis Crick Institute, London, UK., Ambrose K; The Francis Crick Institute, London, UK., Barrell S; The Francis Crick Institute, London, UK., Beale R; The Francis Crick Institute, London, UK.; University College London, London, UK., Bineva-Todd G; The Francis Crick Institute, London, UK., Biswas D; University College London, London, UK., Byrne R; The Francis Crick Institute, London, UK., Caidan S; The Francis Crick Institute, London, UK., Cherepanov P; The Francis Crick Institute, London, UK., Churchward L; University College London Hospitals, NHS Foundation Trust, London, UK., Clark G; The Francis Crick Institute, London, UK., Crawford M; The Francis Crick Institute, London, UK., Cubitt L; The Francis Crick Institute, London, UK., Dearing V; The Francis Crick Institute, London, UK., Earl C; The Francis Crick Institute, London, UK., Edwards A; The Francis Crick Institute, London, UK., Ekin C; Health Services Laboratories, London, UK., Fidanis E; The Francis Crick Institute, London, UK., Gaiba A; The Francis Crick Institute, London, UK., Gamblin S; The Francis Crick Institute, London, UK. steve.gamblin@crick.ac.uk., Gandhi S; The Francis Crick Institute, London, UK. sonia.gandhi@crick.ac.uk.; University College London, London, UK. sonia.gandhi@crick.ac.uk.; University College London Hospitals, NHS Foundation Trust, London, UK. sonia.gandhi@crick.ac.uk., Goldman J; The Francis Crick Institute, London, UK., Goldstone R; The Francis Crick Institute, London, UK., Grant PR; Health Services Laboratories, London, UK., Greco M; The Francis Crick Institute, London, UK., Heaney J; University College London Hospitals, NHS Foundation Trust, London, UK., Hindmarsh S; The Francis Crick Institute, London, UK., Houlihan CF; University College London Hospitals, NHS Foundation Trust, London, UK., Howell M; The Francis Crick Institute, London, UK., Hubank M; The Institute of Cancer Research, London, UK.; The Royal Marsden Hospital, Surrey, UK., Hughes D; The Institute of Cancer Research, London, UK., Instrell R; The Francis Crick Institute, London, UK., Jackson D; The Francis Crick Institute, London, UK., Jamal-Hanjani M; University College London, London, UK.; University College London Hospitals, NHS Foundation Trust, London, UK., Jiang M; The Francis Crick Institute, London, UK., Johnson M; The Francis Crick Institute, London, UK., Jones L; The Francis Crick Institute, London, UK., Kanu N; University College London, London, UK., Kassiotis G; The Francis Crick Institute, London, UK., Kirk S; Health Services Laboratories, London, UK., Kjaer S; The Francis Crick Institute, London, UK., Levett A; Health Services Laboratories, London, UK., Levett L; Health Services Laboratories, London, UK., Levi M; University College London Hospitals, NHS Foundation Trust, London, UK., Lu WT; The Francis Crick Institute, London, UK., MacRae JI; The Francis Crick Institute, London, UK., Matthews J; Health Services Laboratories, London, UK., McCoy LE; University College London, London, UK., Moore C; Public Health Wales, Heath Park, Cardiff, UK., Moore D; University College London, London, UK.; University College London Hospitals, NHS Foundation Trust, London, UK., Nastouli E; University College London Hospitals, NHS Foundation Trust, London, UK. eleni.nastouli@nhs.net.; University College London GOS Institute of Child Health, London, UK. eleni.nastouli@nhs.net., Nicod J; The Francis Crick Institute, London, UK., Nightingale L; The Francis Crick Institute, London, UK., Olsen J; The Francis Crick Institute, London, UK., O'Reilly N; The Francis Crick Institute, London, UK., Pabari A; Health Services Laboratories, London, UK., Papayannopoulos V; The Francis Crick Institute, London, UK., Patel N; The Francis Crick Institute, London, UK., Peat N; The Francis Crick Institute, London, UK., Pollitt M; The Francis Crick Institute, London, UK., Ratcliffe P; The Francis Crick Institute, London, UK., Reis e Sousa C; The Francis Crick Institute, London, UK., Rosa A; The Francis Crick Institute, London, UK., Rosenthal R; The Francis Crick Institute, London, UK., Roustan C; The Francis Crick Institute, London, UK., Rowan A; The Francis Crick Institute, London, UK., Shin GY; University College London Hospitals, NHS Foundation Trust, London, UK.; Health Services Laboratories, London, UK., Snell DM; The Francis Crick Institute, London, UK., Song OR; The Francis Crick Institute, London, UK., Spyer MJ; University College London, London, UK., Strange A; The Francis Crick Institute, London, UK., Swanton C; The Francis Crick Institute, London, UK. Charles.Swanton@crick.ac.uk.; University College London, London, UK. Charles.Swanton@crick.ac.uk.; University College London Hospitals, NHS Foundation Trust, London, UK. Charles.Swanton@crick.ac.uk., Turner JMA; The Francis Crick Institute, London, UK., Turner M; Health Services Laboratories, London, UK., Wack A; The Francis Crick Institute, London, UK., Walker PA; The Francis Crick Institute, London, UK., Ward S; The Francis Crick Institute, London, UK.; University College London, London, UK., Wong WK; University College London Hospitals, NHS Foundation Trust, London, UK., Wright J; The Francis Crick Institute, London, UK., Wu M; The Francis Crick Institute, London, UK.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2020 Aug; Vol. 38 (8), pp. 927-931.