Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Ctrl, control"'
Autor:
Michael Koch, Tobias Kockmann, Elke Rodriguez, Ulrike Wehkamp, Paul Hiebert, Maya Ben-Yehuda Greenwald, Dora Stölzl, Hans-Dietmar Beer, Erwin Tschachler, Stephan Weidinger, Sabine Werner, Ulrich Auf dem Keller
Publikováno v:
Koch, M, Kockmann, T, Rodriguez, E, Wehkamp, U, Hiebert, P, Ben-Yehuda Greenwald, M, Stölzl, D, Beer, H-D, Tschachler, E, Weidinger, S, Werner, S & auf dem Keller, U 2023, ' Quantitative proteomics identifies reduced NRF2 activity and mitochondrial dysfunction in Atopic Dermatitis ', Journal of Investigative Dermatology, vol. 143, no. 2, pp. 220-237.e7 . https://doi.org/10.1016/j.jid.2022.08.048
Journal of Investigative Dermatology, 143 (2)
Journal of Investigative Dermatology, 143 (2)
Atopic dermatitis is the most common inflammatory skin disease and is characterized by a deficient epidermal barrier and cutaneous inflammation. Genetic studies suggest a key role of keratinocytes in atopic dermatitis pathogenesis, but the alteration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b87ecb94d48f8822feeb7012eff45a0
https://www.zora.uzh.ch/id/eprint/227346/
https://www.zora.uzh.ch/id/eprint/227346/
Publikováno v:
IBRO Neuroscience Reports, Vol 11, Iss, Pp 183-193 (2021)
IBRO Neuroscience Reports
IBRO Neuroscience Reports
Status epilepticus (SE) is a neurological emergency, and delayed management can lead to higher morbidity and mortality. It is thought that prolonged seizures stimulate stem cells in the hippocampus and that epileptogenesis may arise from aberrant con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d32bbffc59bb8d8e87e50315da1131
http://www.sciencedirect.com/science/article/pii/S2667242121000440
http://www.sciencedirect.com/science/article/pii/S2667242121000440
Autor:
Sebastian Albinsson, Mario Grossi, Johan Holmberg, Catarina Rippe, Karl Swärd, Fatima Daoud, Azra Alajbegovic
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims YAP (Yap1) and TAZ (Wwtr1) are transcriptional co-activators and downstream effectors of the Hippo pathway, which play crucial roles in organ size control and cancer pathogenesis. Genetic deletion of YAP/TAZ has shown their critical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98cb57df31ea17debc2f76426b849444
https://doi.org/10.1016/j.jcmgh.2020.09.014
https://doi.org/10.1016/j.jcmgh.2020.09.014
Autor:
Djedjiga Abdelhamid, Massoud Mirshahi, Shahsoltan Mirshahi, Iman Al dybiat, Meriem Belalou, Marc Pocard, Matti Ullah, Jeannette Soria, Shahid Shah
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 12, Pp 809-819 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Aim Evaluation of fibrin role on cancer cells implantation in injured tissues and studying the molecular mechanism of cancer cell interaction with the peritoneal damage. Material and methods Mouse colon cancer (CT26) and human mesothelial cells (HMCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6baa12bc8e7c11ff2fbb3e3377a366
http://www.sciencedirect.com/science/article/pii/S1476558620301524
http://www.sciencedirect.com/science/article/pii/S1476558620301524
Autor:
Saleh I. Alqasoumi, Saud M. Alsanad, Osama A. Alkhamees, Talha Jawaid, Ila Shukla, Mehnaz Kamal, Lubna Azmi, Ch V Rao, Amani S. Awaad
Publikováno v:
Saudi Pharmaceutical Journal : SPJ
Saudi Pharmaceutical Journal, Vol 28, Iss 4, Pp 519-527 (2020)
Saudi Pharmaceutical Journal, Vol 28, Iss 4, Pp 519-527 (2020)
Alcoholic liver disease (ALD) is a broad-spectrum disorder, covering fatty liver, cirrhosis, alcoholic hepatitis and in extreme untreated condition hepatocellular carcinoma (HCC) may also develop. Cladonia rangiferina (CR) is a class of lichen having
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244fdc5038af7c8db490be773e739be3
https://doi.org/10.1016/j.jsps.2020.03.003
https://doi.org/10.1016/j.jsps.2020.03.003
Autor:
Cuiting Luo, Calvin W. L. Chin, Michael R. Zile, Bo Bai, Weiping Han, Wan Ting Tay, Yanyun Fu, Yu Wang, Jayantha Gunaratne, Philip Lee, Wulin Yang, Hannah Lee Foon, Kangmin Yang, Carolyn S.P. Lam, Aimin Xu
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 924-937 (2019)
JACC: Basic to Translational Science, Vol 4, Iss 8, Pp 924-937 (2019)
Visual Abstract
Highlights • The lean diabetic SKO mouse represents a novel and validated murine model of HFpEF. • The SKO HFpEF mouse model recapitulates the cardiac structure and function abnormalities in lean diabetic HFpEF patients in As
Highlights • The lean diabetic SKO mouse represents a novel and validated murine model of HFpEF. • The SKO HFpEF mouse model recapitulates the cardiac structure and function abnormalities in lean diabetic HFpEF patients in As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b771bfcd7e18dbced5868c49fe66943d
https://doi.org/10.1016/j.jacbts.2019.07.008
https://doi.org/10.1016/j.jacbts.2019.07.008
Autor:
Katleen Lemaire, Abhijit Babaji Shinde, Stefan Vinckier, Frans Schuit, Ritesh K. Baboota, Marc Fransen, Paul P. Van Veldhoven, Myriam Baes
Publikováno v:
Molecular Metabolism, Vol 22, Iss, Pp 71-83 (2019)
Molecular Metabolism
Molecular Metabolism
Objectives Peroxisomes play a crucial role in lipid and reactive oxygen species metabolism, but their importance for pancreatic β-cell functioning is presently unknown. To examine the contribution of peroxisomal metabolism to β-cell homeostasis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5a12bcfecad16b8dd47f4992e6fe7f4
http://www.sciencedirect.com/science/article/pii/S2212877818311153
http://www.sciencedirect.com/science/article/pii/S2212877818311153
Autor:
Philip J. Smaldino, Amy Krans, Yi-Ju Tseng, Yuh-Hwa Wang, Adam E. Richardson, Katelyn M. Green, James P. Vaughn, Meredith E. Sharlow, Eric D. Routh, Peter K. Todd, Melissa A. Smaldino, Siara N. Sandwith, Antonio E. Chambers, Michael A. Reisinger, Heather M Raimer
Publikováno v:
The Journal of Biological Chemistry
GGGGCC (G4C2) hexanucleotide repeat expansions in the endosomal trafficking gene C9orf72 are the most common genetic cause of ALS and frontotemporal dementia. Repeat-associated non-AUG (RAN) translation of this expansion through near-cognate initiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3ff8599557e7269f89d5bb5b0f3c3c
http://europepmc.org/articles/PMC8326427
http://europepmc.org/articles/PMC8326427
Autor:
Lauren A. Hauser, Marek Napierala, Amanda Clark, Jennifer M. Farmer, Kimal Rajapakshe, David A. Lynch, Peining Xu, Clementina Mesaros, Dean P. Edwards, Yu-Yun Chen, Ian A. Blair, Shixia Huang, Cristian Coarfa, Jill S. Napierala
Publikováno v:
Molecular & Cellular Proteomics : MCP
Identifying biomarkers is important for assessment of disease progression, prediction of symptom development, and determination of treatment effectiveness. While unbiased analyses of differential gene expression using next-generation sequencing metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239d5431dbcbfd7df7c1a470624aee8d
http://europepmc.org/articles/PMC8214145
http://europepmc.org/articles/PMC8214145
Autor:
Malte P. Suppli, Cristina Alonso, Bruno Sangro, Ekaterina Zhuravleva, Rocio I.R. Macias, Filip K. Knop, Emma Eizaguirre, Manuel Romero-Gómez, Jesus M. Banales, Alvaro Santos-Laso, Raul Jimenez-Agüero, Jesper B. Andersen, Marco Arrese Jimenez, Monika Lewinska, Stine Karlsen Oversoe, Flair José Carrilho, Gerda Elisabeth Villadsen, María Jesús Pareja, Claudia Pms de Oliveira, Thomas Decaens, Enara Arretxe
Publikováno v:
EBioMedicine, Vol 73, Iss, Pp 103661-(2021)
Lewinska, M, Santos-Laso, A, Arretxe, E, Alonso, C, Zhuravleva, E, Jimenez-Agüero, R, Eizaguirre, E, Pareja, M J, Romero-Gómez, M, Arrese, M, Suppli, M P, Knop, F K, Oversoe, S K, Villadsen, G E, Decaens, T, Carrilho, F J, de Oliveira, C P, Sangro, B, Macias, R I R, Banales, J M & Andersen, J B 2021, ' The altered serum lipidome and its diagnostic potential for Non-Alcoholic Fatty Liver (NAFL)-associated hepatocellular carcinoma ', EBioMedicine, vol. 73, pp. 103661 . https://doi.org/10.1016/j.ebiom.2021.103661
Addi. Archivo Digital para la Docencia y la Investigación
instname
EBioMedicine
Digital.CSIC. Repositorio Institucional del CSIC
Lewinska, M, Santos-Laso, A, Arretxe, E, Alonso, C, Zhuravleva, E, Jimenez-Agüero, R, Eizaguirre, E, Pareja, M J, Romero-Gómez, M, Arrese, M, Suppli, M P, Knop, F K, Oversoe, S K, Villadsen, G E, Decaens, T, Carrilho, F J, de Oliveira, C P, Sangro, B, Macias, R I R, Banales, J M & Andersen, J B 2021, ' The altered serum lipidome and its diagnostic potential for Non-Alcoholic Fatty Liver (NAFL)-associated hepatocellular carcinoma ', EBioMedicine, vol. 73, pp. 103661 . https://doi.org/10.1016/j.ebiom.2021.103661
Addi. Archivo Digital para la Docencia y la Investigación
instname
EBioMedicine
Digital.CSIC. Repositorio Institucional del CSIC
[Background] Non-alcoholic fatty liver disease (NAFLD) is affecting more people globally. Indeed, NAFLD is a spectrum of metabolic dysfunctions that can progress to hepatocellular carcinoma (NAFLD-HCC). This development can occur in a non-cirrhotic l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da069c4db0add797224a1fd8ecbf5f1
https://doi.org/10.2139/ssrn.3894905
https://doi.org/10.2139/ssrn.3894905