Zobrazeno 1 - 10
of 6 020
pro vyhledávání: '"CtDNA"'
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Background Circulating tumour DNA (ctDNA) is a subset of cell free DNA (cfDNA) released by tumour cells into the bloodstream. Circulating tumour DNA has shown great potential as a biomarker to inform treatment in cancer patients. Collecting
Externí odkaz:
https://doaj.org/article/a4be45a40a9442dfb98ecaae7f1dfd4a
Autor:
Jennifer H. Chen, Sridevi Addanki, Dhruvajyoti Roy, Roland Bassett, Ekaterina Kalashnikova, Erik Spickard, Henry M. Kuerer, Salyna Meas, Vanessa N. Sarli, Anil Korkut, Jason B. White, Gaiane M. Rauch, Debu Tripathy, Banu K. Arun, Carlos H. Barcenas, Clinton Yam, Himanshu Sethi, Angel A. Rodriguez, Minetta C. Liu, Stacy L. Moulder, Anthony Lucci
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Triple negative breast cancer (TNBC) is an aggressive subtype with poor prognosis. We aimed to determine whether circulating tumor DNA (ctDNA) and circulating tumor cell (CTC) could predict response and long-term outcomes to neoad
Externí odkaz:
https://doaj.org/article/f34717845d704cca8a1c2809ca2e3328
Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 67, Iss 3, Pp 492-501 (2024)
Current advances in the understanding of the lung cancer landscape have drastically changed the approach to treating a patient with lung carcinoma. The field has progressed from analyzing single gene to using advanced techniques like next-generation
Externí odkaz:
https://doaj.org/article/7eec3fbec96f48c9a529e43f3d558b5e
Autor:
Ryan D. Gentzler, John Guittar, Akash Mitra, Wade T. Iams, Terri Driessen, Regina Schwind, Michelle M. Stein, Kristiyana Kaneva, Seung Won Hyun, Yan Liu, Adam J. Dugan, Cecile Rose T. Vibat, Chithra Sangli, Jonathan Freaney, Zachary Rivers, Josephine L. Feliciano, Christine Lo, Kate Sasser, Rotem Ben-Shachar, Halla Nimeiri, Jyoti D. Patel, Aadel A. Chaudhuri
Publikováno v:
Oncology and Therapy, Vol 12, Iss 3, Pp 509-524 (2024)
Abstract Introduction A dynamic molecular biomarker that can identify early efficacy of immune checkpoint inhibitor (ICI) therapy remains an unmet clinical need. Here we evaluate if a novel circulating tumor DNA (ctDNA) assay, xM, used for treatment
Externí odkaz:
https://doaj.org/article/e9866030c92c41cc8282109a54d5780e
Autor:
Hyojung Ryu, Ji-Hoon Kim, Yeo Jin Kim, Hahyeon Jeon, Byoung-Chul Kim, Yeonsu Jeon, Yeonkyung Kim, Hyebin Bak, Younghui Kang, Changjae Kim, Hyojin Um, Ji-Hye Ahn, Hwi Hyun, Byung Chul Kim, Inho Song, Sungwon Jeon, Jong Bhak, Eon Chul Han
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background Colon cancer ranks as the second most lethal form of cancer globally. In recent years, there has been active investigation into using the methylation profile of circulating tumor DNA (ctDNA), derived from blood, as a promising ind
Externí odkaz:
https://doaj.org/article/d20c621c5ea84b5b91fa811429ad0999
Autor:
E. Lukacova, Z. Hanzlikova, P. Podlesnyi, T. Sedlackova, T. Szemes, M. Grendar, M. Samec, T. Hurtova, B. Malicherova, K. Leskova, J. Budis, T. Burjanivova
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Malignant melanoma (MM) is known for its abundance of genetic alterations and a tendency for rapid metastasizing. Identification of novel plasma biomarkers may enhance non-invasive diagnostics and disease monitoring. Initially, we examined c
Externí odkaz:
https://doaj.org/article/7a631594771c48c4ad341dc85f188e5a
Publikováno v:
Current Oncology, Vol 31, Iss 7, Pp 3808-3814 (2024)
The application of adjuvant treatment has significantly enhanced the survival of patients with resectable non-small cell lung cancer (NSCLC) carrying driver gene mutations. However, adjuvant-targeted therapy remains controversial for some NSCLC patie
Externí odkaz:
https://doaj.org/article/12fd65a45b334748b4b06db515420ffa
Autor:
Minjung Kim, Juntae Park, Seonghee Oh, Byeong-Ho Jeong, Yuree Byun, Sun Hye Shin, Yunjoo Im, Jong Ho Cho, Eun-Hae Cho
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Detecting aberrant cell-free DNA (cfDNA) methylation is a promising strategy for lung cancer diagnosis. In this study, our aim is to identify methylation markers to distinguish patients with lung cancer from healthy individuals. Additionally
Externí odkaz:
https://doaj.org/article/f4baed5d1ad8448b9174eda87a12c4c1
Autor:
Nana Guo, Qingxin Zhou, Meng Zhang, Xiaowei Chen, Baoqi Zeng, Shanshan Wu, Hongmei Zeng, Mopei Wang, Fei Ma, Feng Sun
Publikováno v:
Journal of the National Cancer Center, Vol 4, Iss 2, Pp 153-161 (2024)
Objective: Circulating tumor DNA (ctDNA) is increasingly being used as a potential prognostic biomarker in cancer patients. We aimed to assess the prognostic value of ctDNA in different subtypes of breast cancer patients throughout the whole treatmen
Externí odkaz:
https://doaj.org/article/689c57a237054c7c801fe76b03245eef
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Programmed Death Receptor 1 (PD-1) inhibitors, when combined with chemotherapy, have exhibited notable effectiveness in enhancing the survival outcomes of patients afflicted with advanced gastric cancer. However, it is important to acknowled
Externí odkaz:
https://doaj.org/article/f05c8893e378418196ce28738cd77bf7