Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Csoka Imre Christian Francis"'
Autor:
Chi Hung Nguyen, Edward Arnold, Alain Philippe Poncelet, David Grierson, Stephen H. Hughes, Daniel M. Himmel, Said Oumouch, Christophe Meyer, Sophie Coupa, Jerome Guillemont, Abdellah Benjahad, Koen Andries, Kalyan Das, Arthur D. Clark, Csoka Imre Christian Francis
Publikováno v:
Journal of medicinal chemistry
In the treatment of AIDS, the efficacy of all drugs, including non-nucleoside inhibitors (NNRTIs) of HIV-1 reverse transcriptase (RT), has been limited by the rapid appearance of drug-resistant viruses. Lys103Asn, Tyr181Cys, and Tyr188Leu are some of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83adb8b43e47995658d1595b261bb411
https://doi.org/10.1021/jm0500323
https://doi.org/10.1021/jm0500323
Autor:
Karine Courte, Marie-Pierre De Bethune, Rudi Pauwels, Jérome Guillemont, Csoka Imre Christian Francis, Chi Hung Nguyen, Alain Poncelet, Emile Bisagni, Sophie Coupa, David S. Grierson, Dominique Mabire, Abdellah Benjahad, Koen Andries, Claude Monneret
Publikováno v:
Journal of medicinal chemistry
The 4-benzyl and 4-benzoyl-3-dimethylaminopyridinones 13 and 14 are representatives of a new class of highly potent non nucleoside type inhibitors of HIV-1 reverse transcriptase. To conduct SAR studies on these two lead compounds, 102 new analogues w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26af9a522cccb06a81c98206ba082c3b
https://doi.org/10.1021/jm0407658
https://doi.org/10.1021/jm0407658
Autor:
Dominique Jean-Pierre Mabire, Koen Andries, Chi Hung Nguyen, Alain Philippe Poncelet, Martine Croisy, Daniel M. Himmel, Christophe Meyer, Claude Monneret, Eddy Arnold, R Pauwels, Marie-Pierre de Béthune, Sophie Coupa, Kalyan Das, David Grierson, Jerome Emile Georges Guillemont, Abdellah Benjahad, Csoka Imre Christian Francis, Emile Bisagni
Publikováno v:
Journal of medicinal chemistry
In a program to optimize the anti-HIV activity of the 4-benzyl and 4-benzoyl-3-dimethylaminopyridinones 9 and 10, lead compounds in a new class of highly potent non-nucleoside type inhibitors of HIV-1 reverse transcriptase, modification of the alkyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::267886123a41e6a1498b86721308c0e8
https://pubmed.ncbi.nlm.nih.gov/15771439
https://pubmed.ncbi.nlm.nih.gov/15771439