ASXL1/TET2 genotype-based risk stratification outperforms ASXL1 mutational impact and is independent of mutant variant allele fractions in chronic myelomonocytic leukemia.

Autor: Csizmar CM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Gurney M; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Kanagal-Shamanna R; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX., Chien K; Division of Cancer Medicine, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX., Hammond D; Division of Cancer Medicine, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX., Lasho TL; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Finke CM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Dean C; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Natu A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Mangaonkar AA; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Al-Kali A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Gangat N; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Tefferi A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Alkhateeb H; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Garcia-Manero G; Division of Cancer Medicine, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX., Komrokji RS; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL., Ali NA; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL., Padron E; Department of Malignant Hematology, H. Lee Moffitt Cancer Center, Tampa, FL., Montalban-Bravo G; Division of Cancer Medicine, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX., Patnaik MM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN. patnaik.mrinal@mayo.edu.

Publikováno v: Haematologica [Haematologica] 2024 Oct 01; Vol. 109 (10), pp. 3419-3425. Date of Electronic Publication: 2024 Oct 01.

FLT3 inhibitors potentially improve response rates in acute myeloid leukemia harboring t(6;9)( DEK::NUP214 ): The Mayo Clinic experience.

Autor: Csizmar CM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Saliba AN; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Greipp PT; Division of Hematopathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN., Alkhateeb H; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Begna KH; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Foran JM; Division of Hematology and Medical Oncology, Department of Medicine, Mayo Clinic, Jacksonville, FL., Gangat N; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Hogan WJ; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Hook CC; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Litzow MR; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Mangaonkar AA; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Palmer JM; Division of Hematology and Medical Oncology, Department of Medicine, Mayo Clinic, Phoenix, AZ., Pardanani A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Shah MV; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Tefferi A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Torghabeh MH; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Wolanskyj-Spinner AP; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Patnaik MM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN., Kaufmann SH; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN. kaufmann.scott@mayo.edu., Al-Kali A; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN. alkali.aref@mayo.edu.

Publikováno v: Haematologica [Haematologica] 2024 Jun 20. Date of Electronic Publication: 2024 Jun 20.

AMPK inhibition sensitizes acute leukemia cells to BH3 mimetic-induced cell death.

Autor: Jia J; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Ji W; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Saliba AN; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA., Csizmar CM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA., Ye K; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Hu L; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; University of Science and Technology of China, Hefei, 230026, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Peterson KL; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Schneider PA; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Meng XW; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Venkatachalam A; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Patnaik MM; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA., Webster JA; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA., Smith BD; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA., Ghiaur G; Adult Leukemia Program, Sidney Kimmel Cancer Center at Johns Hopkins, Baltimore, MD, 21287, USA., Wu X; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA., Zhong J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA., Pandey A; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.; Manipal Academy of Higher Education, Manipal, 576104, Kamataka, India., Flatten KS; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA., Deng Q; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Wang H; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China., Kaufmann SH; Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. Kaufmann.Scott@Mayo.edu., Dai H; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, China. daih@cmpt.ac.cn.; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, China. daih@cmpt.ac.cn.; Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN, 55905, USA. daih@cmpt.ac.cn.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2024 Apr; Vol. 31 (4), pp. 405-416. Date of Electronic Publication: 2024 Mar 27.

84-Year-Old Female With Easy Bruising.

Autor: Csizmar CM; Resident in Internal Medicine, Mayo Clinic School of Graduate Medical Education, Mayo Clinic, Rochester, MN, USA., Abraham HM; Resident in Internal Medicine, Mayo Clinic School of Graduate Medical Education, Mayo Clinic, Rochester, MN, USA., Thompson CA; Advisor to residents and Consultant in Division of Hematology, Mayo Clinic, Rochester, MN, USA. Electronic address: thompson.carrie@mayo.edu.

Publikováno v: Mayo Clinic proceedings [Mayo Clin Proc] 2023 Jul; Vol. 98 (7), pp. 1079-1084. Date of Electronic Publication: 2023 Jun 07.

Primary Cardiac Lymphoma: Three Case Reports and a Review of the Literature.

Autor: Csizmar CM; School of Medicine, University of Minnesota, Minneapolis, MN, USA., Sachs Z; Division of Hematology, Oncology, and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA., Cayci Z; Department of Radiology, University of Minnesota, Minneapolis, MN, USA., Bu L; Division of Hematopathology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Linden MA; Division of Hematopathology, Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA.

Publikováno v: Open journal of blood diseases [Open J Blood Dis] 2021 Dec; Vol. 11 (4), pp. 120-132. Date of Electronic Publication: 2021 Dec 02.