Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Csilla Keskeny"'
Autor:
Konstantin Helmsauer, Maria E. Valieva, Salaheddine Ali, Rocío Chamorro González, Robert Schöpflin, Claudia Röefzaad, Yi Bei, Heathcliff Dorado Garcia, Elias Rodriguez-Fos, Montserrat Puiggròs, Katharina Kasack, Kerstin Haase, Csilla Keskeny, Celine Y. Chen, Luis P. Kuschel, Philipp Euskirchen, Verena Heinrich, Michael I. Robson, Carolina Rosswog, Joern Toedling, Annabell Szymansky, Falk Hertwig, Matthias Fischer, David Torrents, Angelika Eggert, Johannes H. Schulte, Stefan Mundlos, Anton G. Henssen, Richard P. Koche
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
MYCN amplification is common in neuroblastomas. Here the authors analyse the MYCN amplicon structure and its epigenetic regulation by integrating short- and longread genomic and epigenomic data and find two classes of MYCN amplicons in neuroblastomas
Externí odkaz:
https://doaj.org/article/c5b9fcaacd9648e4831d4de98b3e2479
Autor:
Tobias Raisch, Elisa Izaurralde, Oliver Weichenrieder, Cátia Igreja, Annamaria Sgromo, Dipankar Bhandari, Csilla Keskeny
Publikováno v:
Genes & Development. 33:236-252
The multisubunit CCR4–NOT mRNA deadenylase complex plays important roles in the posttranscriptional regulation of gene expression. The NOT4 E3 ubiquitin ligase is a stable component of the CCR4–NOT complex in yeast but does not copurify with the
Autor:
Min-Yi Chung, Eugene Valkov, Cátia Igreja, Ramona Weber, Csilla Keskeny, Elisa Izaurralde, Markus Landthaler, Ulrike Zinnall
Publikováno v:
Cell Rep
Current models of mRNA turnover indicate that cytoplasmic degradation is coupled with translation. However, our understanding of the molecular events that coordinate ribosome transit with the mRNA decay machinery is still limited. Here, we show that
Autor:
Csilla Keskeny, Annamaria Sgromo, Elisa Izaurralde, Oliver Weichenrieder, Tobias Raisch, Charlotte Backhaus, Vikram Alva
Drosophila melanogaster Bag-of-marbles (Bam) promotes germline stem cell (GSC) differentiation by repressing the expression of mRNAs encoding stem cell maintenance factors. Bam interacts with Benign gonial cell neoplasm (Bgcn) and the CCR4 deadenylas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7638b62a63418c12d4a7216a40b9b5
https://europepmc.org/articles/PMC5824357/
https://europepmc.org/articles/PMC5824357/
Autor:
Zsolt Rázga, Zoltán Kónya, Renáta Gáspár, Dávid Kovács, Imre Boros, Mónika Kiricsi, Dániel Madarász, Tímea Tóth, Nóra Igaz, Csilla Keskeny, Péter Bélteky
Publikováno v:
Scientific Reports
Loss of function of the tumour suppressor p53 observed frequently in human cancers challenges the drug-induced apoptotic elimination of cancer cells from the body. This phenomenon is a major concern and provides much of the impetus for current attemp