Výsledky vyhledávání - "Csilla Csank"

Mitogen-activated protein kinase-defective Candida albicans is avirulent in a novel model of localized murine candidiasis

Autor: Henrik Jeldtoft Jensen, Faisal A. Guhad, Csilla Csank, Jann Hau, David Y. Thomas, Malcolm Whiteway, Bent Aalbæk, Othman A. Mohamed, Doreen Harcus

Publikováno v: FEMS Microbiology Letters. 166:135-139

Candida albicans strains with a deletion of the mitogen-activated protein kinase CEK1 gene are defective in the yeast to hyphal transition on solid surfaces in vitro. The virulence of a cek1 delta/cek1 delta null mutant strain was compared with its w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb5c784615dc16e3d84096ebdddf7c3
https://doi.org/10.1111/j.1574-6968.1998.tb13194.x

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Reduced pathogenicity of aCandida albicansMAP kinase phosphatase (CPP1) mutant in the murine mastitis model

Autor: Henrik Jeldtoft Jensen, Csilla Csank, David Y. Thomas, Faisal A. Guhad, Malcolm Whiteway, Jann Hau

Publikováno v: Europe PubMed Central
University of Copenhagen

Candida albicans strains with a deletion of the mitogen-activated protein kinase tyrosine phosphatase gene (CPP1) are derepressed in the yeast-to-hyphal transition on solid surfaces in vitro at ambient temperatures and this gene is therefore required

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d58872cc2a5756bb36b02a9b2adc86
https://doi.org/10.1111/j.1699-0463.1998.tb00257.x

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Roles of the Candida albicans Mitogen-Activated Protein Kinase Homolog, Cek1p, in Hyphal Development and Systemic Candidiasis

Autor: Csilla Csank, Othman A. Mohamed, David Y. Thomas, Sylvain Meloche, Malcolm Whiteway, Klaus Schröppel, Doreen Harcus, Ekkehard Leberer

Publikováno v: Scopus-Elsevier

Extracellular signal-regulated protein kinase (ERK, or mitogen-activated protein kinase [MAPK]) regulatory cascades in fungi turn on transcription factors that control developmental processes, stress responses, and cell wall integrity. CEK1 encodes a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbed3fcafb471fd954e070e53323edf
https://doi.org/10.1128/iai.66.6.2713-2721.1998

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Derepressed Hyphal Growth and Reduced Virulence in a VH1 Family-related Protein Phosphatase Mutant of the Human PathogenCandida albicans

Autor: Daniel Dignard, Martin Röllinghoff, Constantin Makris, Klaus Schröppel, Malcolm Whiteway, Csilla Csank, David Y. Thomas, Sylvain Meloche

Publikováno v: Molecular Biology of the Cell. 8:2539-2551

Mitogen-activated protein (MAP) kinases are pivotal components of eukaryotic signaling cascades. Phosphorylation of tyrosine and threonine residues activates MAP kinases, but either dual-specificity or monospecificity phosphatases can inactivate them

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a640c01bdefd6af1cc8406170494467
https://doi.org/10.1091/mbc.8.12.2539

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Repression of Hyphal Proteinase Expression by the Mitogen-Activated Protein (MAP) Kinase Phosphatase Cpp1p of Candida albicans Is Independent of the MAP Kinase Cek1p

Autor: Csilla Csank, Martin Röllinghoff, Malcolm Whiteway, Katrin Sprösser, David Y. Thomas, Klaus Schröppel

Publikováno v: Infection and Immunity. 68:7159-7161

Cpp1p is a putative mitogen-activated protein (MAP) kinase phosphatase that suppresses Candida albicans hyphal formation at 25°C through its probable substrate, the Cek1p filamentation MAP kinase. Here we report that expression of the serum-induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c28e05b13d66a44eeb353a7673295f7
https://doi.org/10.1128/iai.68.12.7159-7161.2000

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Nuclear pre-mRNA introns: analysis and comparison of intron sequences fromTetrahymena thermophilaand other eukaryotes

Autor: Duane W. Martindale, Csilla Csank, Frances M. Taylor

Publikováno v: Nucleic Acids Research. 18:5133-5141

We have sequenced 14 introns from the ciliate Tetrahymena thermophila and include these in an analysis of the 27 intron sequences available from seven T. thermophila protein-encoding genes. Consensus 5' and 3' splice junctions were determined and fou

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https://doi.org/10.1093/nar/18.17.5133

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Candida albicans RHO1 is required for cell viability in vitro and in vivo

Autor: Vivian Berlin, Csilla Csank, Susan E. Smith, Mahmoud A. Ghannoum, Guadalupe Reyes

Publikováno v: FEMS yeast research. 2(2)

In Saccharomyces cerevisiae, Rho1p plays an important role in cell wall integrity by regulating beta-1,3-glucan synthase, Pkc1p and the actin cytoskeleton. To determine the physiological role of Rho1p in the dimorphic fungus Candida albicans, the maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e435563927a862df4d19d7b09258ac3
https://pubmed.ncbi.nlm.nih.gov/12702298

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Three yeast proteome databases: YPD, PombePD, and Ca1PD (MycoPathPD)

Autor: Janice E. Kranz, Kathy E. O'Neill, James I. Garrels, Csilla Csank, Mary E. Mangan, Marek S. Skrzypek, Peter E. Hodges, Jodi E. Hirschman, Laura S. Robertson, Maria C. Costanzo, Joan E. Brooks

Publisher Summary Proteome's fungal databases, YPD (for Saccharomyces cerevisiae), PombePD (for Schizosaccharomyces pombe), and CalPD (for Candida albicans), work together to present a comprehensive view of the molecular and cell biology of the genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2588d038aab686604cf40303d016f9d8
https://doi.org/10.1016/s0076-6879(02)50973-3

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